Search Results - "Lünemann, JD"

Intravenous immunoglobulin in neurology—mode of action and clinical efficacy by Lünemann, Jan D., Nimmerjahn, Falk, Dalakas, Marinos C.

“…Key Points Intravenous immunoglobulin (IVIg) is established for the treatment of several inflammatory neurological diseases, including Guillain–Barré syndrome,…”
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Antiviral immune response in patients with multiple sclerosis and healthy siblings by Comabella, M., Montalban, X., Horga, A., Messmer, B., Kakalacheva, K., Strowig, T., Caballero, E., Münz, C., Lünemann, JD

“…The objective of this study was to determine the immune responses to candidate viral triggers of multiple sclerosis in patients and healthy siblings raised in…”
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Efficacy of Intravenous Immunoglobulin in Neurological Diseases by Lünemann, Jan D., Quast, Isaak, Dalakas, Marinos C.

“…Owing to its anti-inflammatory efficacy in various autoimmune disease conditions, intravenous immunoglobulin (IVIG)—pooled IgG obtained from the plasma of…”
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TNF-related apoptosis inducing ligand (TRAIL) as a potential response marker for interferon-beta treatment in multiple sclerosis by Wandinger, Klaus-Peter, Lünemann, Jan D, Wengert, Oliver, Bellmann-Strobl, Judith, Aktas, Orhan, Weber, Alexandra, Grundström, Eva, Ehrlich, Stefan, Wernecke, Klaus-D, Volk, Hans-Dieter, Zipp, Frauke

“…Many patients with multiple sclerosis do not respond to interferon beta, which is widely used as an immunomodulatory treatment in this disease. We aimed to…”
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Death Ligand TRAIL Induces No Apoptosis but Inhibits Activation of Human (Auto)antigen-Specific T Cells by Lunemann, Jan D, Waiczies, Sonia, Ehrlich, Stefan, Wendling, Uwe, Seeger, Bibiane, Kamradt, Thomas, Zipp, Frauke

“…TNF-related apoptosis-inducing ligand (TRAIL), a member of the TNF superfamily, induces apoptosis in susceptible cells, which can be both malignant and…”
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Progressive change in primary progressive multiple sclerosis normal-appearing white matter: a serial diffusion magnetic resonance imaging study by Schmierer, Klaus, Altmann, Daniel R, Kassim, Nadja, Kitzler, Hagen, Kerskens, Christian M, Doege, Claudia A, Aktas, Orhan, Lünemann, Jan D, Miller, David H, Zipp, Frauke, Villringer, Arno

“…In spite of marked disability, patients with primary progressive multiple sclerosis (PPMS) display smaller lesion volumes on conventional magnetic resonance…”
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Acute combined central and peripheral inflammatory demyelination by Katchanov, J, Lünemann, J D, Masuhr, F, Becker, D, Ahmadi, M, Bösel, J, Zschenderlein, R, Bamborschke, S, Klingebiel, R

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Elevated Bcl-X L levels correlate with T cell survival in multiple sclerosis by Waiczies, Sonia, Weber, Alexandra, Lünemann, Jan D., Aktas, Orhan, Zschenderlein, Rolf, Zipp, Frauke

“…T cell resistance towards apoptotic elimination by activation-induced cell death (AICD) might be a crucial pathogenic feature of multiple sclerosis (MS). Since…”
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Rapid typing of Borrelia burgdorferi sensu lato species in specimens from patients with different manifestations of Lyme borreliosis by LÜNEMANN, Jan D, ZARMAS, Silvia, PRIEM, Susanne, FRANZ, Juliane, ZSCHENDERLEIN, Rolf, ABERER, Elisabeth, KLEIN, Rolf, SCHOULS, Leo, BURMESTER, Gerd R, KRAUSE, Andreas

“…To further investigate the pathogenic potential of different Borrelia burgdorferi genospecies, specimens from 27 patients with different manifestations of Lyme…”
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Cross-sectional and longitudinal analysis of myelin-reactive T cells in patients with multiple sclerosis by LÜNEMANN, Jan D, RÜCKERT, Sandra, KERN, Florian, WENDLING, Uwe, VAN DER ZEE, Ruud, VOLK, Hans D, ZIPP, Frauke

“…Activated myelin-specific T cells are thought to mediate inflammatory tissue damage in multiple sclerosis (MS). Applying a large panel of myelin antigens, we…”
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Rhabdomyolysis during interferon-beta 1a treatment by Lünemann, J D, Schwarzenberger, B, Kassim, N, Zschenderlein, R, Zipp, F

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Heterogeneity of Borrelia burgdorferi: etiopathogenetic relevance and clinical implications by Lünemann, J D, Krause, A

“…Of the ten different species of Borrelia (B.) burgdorferi sensu lato which have been characterized to date, only B. burgdorferi sensu stricto, B. garinii and…”
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Multiple sclerosis coinciding with Machado-Joseph disease by Röhl, J E, Lünemann, J D, Zimmer, C, Zschenderlein, R, Valdueza, J M

“…Although inflammatory demyelination is considered to be the key feature in multiple sclerosis (MS) pathogenesis, histopathological investigations and MRI…”
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Isolated abducens nerve paresis associated with high titer of anti-asialo-GM1 following Campylobacter jejuni enteritis by Katchanov, Juri, Lünemann, Jan Dirks, Masuhr, Florian, Meisel, Andreas, Möller, Helgard, Zschenderlein, Rolf

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Immunotherapy of chronic inflammatory demyelinating polyneuropathy by Lünemann, J D, Prass, K, Zschenderlein, R

“…Chronic inflammatory demyelinating polyneuropathy (CIDP) is an acquired immune-mediated disease of the peripheral nervous system with an estimated prevalence…”
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Effects of Norepinephrine on Oxygen Consumption of Quiescent and Activated Human Peripheral Blood Mononuclear Cells by LÜNEMANN, JAN D., BUTTGEREIT, FRANK, TRIPMACHER, ROBERT, BAERWALD, CHRISTOPH G.O., BURMESTER, GERD-RÜDIGER, KRAUSE, ANDREAS

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Norepinephrine inhibits energy metabolism of human peripheral blood mononuclear cells via adrenergic receptors by Lünemann, J D, Buttgereit, F, Tripmacher, R, Baerwald, C G, Burmester, G R, Krause, A

“…Previous studies demonstrated that the adaptive response to stressors and inflammatory signals involves the activation of the autonomous [corrected] nervous…”
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Thalamo-mesencephalic infarction as a single manifestation of combined factor V Leiden and antiphospholipid syndrome by Wandinger, Klaus-Peter, Klingebiel, Randolf, Lünemann, Jan Dirks, Zimmer, Claus, Ziemer, Sabine, Zschenderlein, Rolf

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Rapid Typing of Borrelia burgdorferi Sensu Lato Species in Specimens from Patients with Different Manifestations of Lyme Borreliosis by Lünemann, Jan D., Zarmas, Silvia, Priem, Susanne, Franz, Juliane, Zschenderlein, Rolf, Aberer, Elisabeth, Klein, Rolf, Schouls, Leon, Burmester, Gerd R., Krause, Andreas

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The role of apoptosis in neuroinflammation by Zipp, F, Aktas, O, Lünemann, J D

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