Search Results - "Lüders, Katja A."
-
1
Genetic dissection of oligodendroglial and neuronal Plp1 function in a novel mouse model of spastic paraplegia type 2
Published in Glia (01-11-2017)“…Proteolipid protein (PLP) is the most abundant integral membrane protein in compact central nervous system myelin, and null mutations of the PLP1 gene cause…”
Get full text
Journal Article -
2
Osmotic pump with potential for bone lengthening distracts continuously in vitro and in vivo
Published in PloS one (14-09-2023)“…Background In pediatric orthopedics, long bone lengthening procedures are routinely performed using manual, motorized or magnetically controlled implants. This…”
Get full text
Journal Article -
3
CMTM6 expressed on the adaxonal Schwann cell surface restricts axonal diameters in peripheral nerves
Published in Nature communications (09-09-2020)“…The velocity of nerve conduction is moderately enhanced by larger axonal diameters and potently sped up by myelination of axons. Myelination thus allows rapid…”
Get full text
Journal Article -
4
Isolated catatonia-like executive dysfunction in mice with forebrain-specific loss of myelin integrity
Published in eLife (09-03-2023)“…A key feature of advanced brain aging includes structural defects of intracortical myelin that are associated with secondary neuroinflammation. A similar…”
Get full text
Journal Article -
5
A Preclinical Pilot Study on the Effects of Thermal Ablation on Lamb Growth Plates
Published in Children (Basel) (12-06-2022)“…(1) Background: Thermal ablation has been demonstrated to affect the bone growth of osteoid osteoma in adolescents. Growth modulation due to thermal heat in…”
Get full text
Journal Article -
6
Reduced Volumetric Bone Mineral Density of the Spine in Adolescent Rett Girls with Scoliosis
Published in Children (Basel) (01-12-2022)“…In advanced Rett syndrome (RTT), limited or complete loss of ambulation, nutritional problems and scoliosis are unfavorable factors for bone mineral density…”
Get full text
Journal Article -
7
Comparative study of subtalar arthroereisis, medializing calcaneal osteotomy and the combination of both techniques for the treatment of symptomatic adult flatfeet
Published in Foot and ankle surgery (29-10-2024)“…Symptomatic adult flatfeet are a common problem that is treated with various therapeutic approaches. In this study, three different surgical approaches,…”
Get full text
Journal Article -
8
Scoliosis Treatment With Growth-Friendly Spinal Implants (GFSI) Relates to Low Bone Mineral Mass in Children With Spinal Muscular Atrophy
Published in Journal of pediatric orthopaedics (01-08-2023)“…Children with spinal muscular atrophy (SMA) frequently develop neuromuscular scoliosis at an early age, requiring surgical treatment with growth-friendly…”
Get full text
Journal Article -
9
Maintenance of high proteolipid protein level in adult central nervous system myelin is required to preserve the integrity of myelin and axons
Published in Glia (01-04-2019)“…Proteolipid protein (PLP) is the most abundant integral membrane protein in central nervous system (CNS) myelin. Expression of the Plp‐gene in oligodendrocytes…”
Get full text
Journal Article -
10
Altered bone development with impaired cartilage formation precedes neuromuscular symptoms in spinal muscular atrophy
Published in Human molecular genetics (29-09-2020)“…Abstract Spinal muscular atrophy (SMA) is a fatal neurodegenerative disease of newborns and children caused by mutations or deletions of the survival of…”
Get full text
Journal Article -
11
Children With Spinal Muscular Atrophy With Prior Growth-Friendly Spinal Implants Have Better Results After Definite Spinal Fusion in Comparison to Untreated Patients
Published in Neurosurgery (01-11-2020)“…Abstract BACKGROUND Almost all children with spinal muscular atrophy (SMA) develop a scoliosis during childhood and adolescence. In the last decades,…”
Get full text
Journal Article -
12
Foot Typology, Dynamic and Static Weight Distribution, and Radiographic Changes After Subtalar Arthroereisis in Juvenile Symptomatic Flexible Flat Feet
Published in The Journal of foot and ankle surgery (01-03-2022)“…Flexible flatfoot is among the most common skeletal disorders in childhood. This study describes the dynamic and static correction effects of subtalar…”
Get full text
Journal Article -
13
Spinal Deformities after Childhood Tumors
Published in Cancers (28-11-2020)“…Childhood tumors of the central nervous system (CNS) and other entities affecting the spine are rare. Treatment options vary from surgical biopsy to partial,…”
Get full text
Journal Article -
14
Proteolipid protein modulates preservation of peripheral axons and premature death when myelin protein zero is lacking
Published in Glia (01-01-2016)“…Protein zero (P0) is the major structural component of peripheral myelin. Lack of this adhesion protein from Schwann cells causes a severe dysmyelinating…”
Get full text
Journal Article -
15
Smaller Intervertebral Disc Volume and More Disc Degeneration after Spinal Distraction in Scoliotic Children
Published in Journal of clinical medicine (14-05-2021)“…In recent decades, magnetically controlled growing rods (MCGR) were established to treat progressive early-onset scoliosis. The aim of this investigation was…”
Get full text
Journal Article -
16
-
17
-
18
Osmotic pump with potential for bone lengthening distracts continuously in vitro and in vivo
Published in PloS one (01-01-2023)“…BackgroundIn pediatric orthopedics, long bone lengthening procedures are routinely performed using manual, motorized or magnetically controlled implants. This…”
Get full text
Journal Article