Search Results - "Lücker, P W"

Equipotent inhibition of gastric acid secretion by equal doses of oral or intravenous pantoprazole by HARTMANN, M, EHRLICH, A, FUDER, H, LÜHMANN, R, EMEKLIBAS, S, TIMMER, W, WURST, W, LÜCKER, P. W

“…Background: Pantoprazole is a proton pump inhibitor characterized by a low potential to interact with the cytochrome P450 system, and linear pharmacokinetics…”
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Lack of pharmacodynamic and pharmacokinetic interaction between pantoprazole and phenprocoumon in man by EHRLICH, A, FUDER, H, LÜCKER, P. W, HARTMANN, M, WIECKHORST, G, TIMMER, W, HUBER, R, BIRKEL, M, BLIESATH, H, STEINIJANS, V. W, WURST, W

“…Pantoprazole is a selective proton pump inhibitor characterized by a low potential to interact with the cytochrome P450 enzymes in man. Due to the clinical…”
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Optimizing the Absorption of Valspodar, a P-glycoprotein Modulator, Part I: Selecting an Oral Formulation and Exploring its Clinical Pharmacokinetics/Dynamics by Mueller, E. A., Kovarik, J. M., Üresin, Y., Preisig-Flückiger, S. S., Hensel, S., Lücker, P. W., Holt, B.

“…Valspodar is a cyclosporine D analog used as a chemotherapy adjunct for modifying multidrug resistance. Two studies were sequentially performed to select an…”
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Influence of a fat-rich meal on the pharmacokinetics of a new oral formulation of cyclosporine in a crossover comparison with the market formulation by MUELLER, E. A, KOVARIK, J. M, VAN BREE, J. B, GREVEL, J, LÜCKER, P. W, KUTZ, K

“…The influence of a fat-rich meal on the pharmacokinetics of cyclosporine from a new oral formulation (Sandimmune Neoral) was compared in a randomized, four-way…”
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Twenty-four-hour intragastric pH profiles and pharmacokinetics following single and repeated oral administration of the proton pump inhibitor pantoprazole in comparison to omeprazole by Hartmann, M, Theiss, U, Huber, R, Lühmann, R, Bliesath, H, Wurst, W, Lücker, P W

“…Pantoprazole is a proton pump inhibitor characterized by a low potential to interact with the cytochrome P450 enzyme system in man. Its effect on intragastric…”
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A new method for the determination of the bioavailability of thyroid hormone preparations by Trantow, T, Herzog, R, Gegenheimer, L, Lücker, P W

“…Levothyroxine and levotriiodothyronine are vital hormones that are produced and stored in the thyroid gland. Due to endogenic hormone production and…”
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Study on the absolute bioavailability of quinine and theophylline from tablets after single dose oral administration as compared to intravenous infusion in healthy male non-smoking volunteers by Fuder, H, Herzog, R, Vaupel, W, Wetzelsberger, N, Lücker, P W

“…This investigation was aimed at the determination of the absolute bioavailability of theophylline and quinine after single oral dose administration of Limptar…”
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Bioequivalence of two commercially available tamoxifen tablet formulations in healthy male volunteers by Lorkowski, G, Lücker, P W, Petersen, G, Schnitzler, M, Wetzelsberger, N

“…Tamoxifen, a non-steroidal antiestrogen, is used in the palliative treatment of advanced breast cancer and as an adjuvant therapy after mastectomy. The…”
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Pharmacokinetics of Acetazolamide in Healthy Volunteers after Short- and Long-Term Exposure to High Altitude by Ritschel, Wolfgang A., Paulos, Claudio, Arancibia, Aquiles, Agrawal, Mukul A., Wetzelsberger, Klaus M., Lücker, Peter W.

“…Exposure to high altitude results in significant physiologic changes and may precipitate mountain sickness, ranging from mild symptoms above 2,500 m to severe…”
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Dialysability of dimethindene maleate (Fenistil) from blood after intravenous injection by Kuhn, I, Theiss, U, Rehn, D, Gegenheimer, L, Lücker, P W

“…Dimethindene, an antihistaminic drug, is the treatment of choice in dialysis patients suffering from skin itching. During hemodialysis procedures not only…”
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A pilot study on the determination of the relative bioavailability of levo-thyroxine by Trantow, T, Herzog, R, Fuder, H, Ise, J, Lücker, P W

“…A promising new design aimed at testing bioequivalence of levo-thyroxine preparations in male euthyreotic volunteers was investigated in a pilot study. Healthy…”
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Pharmacokinetics and relative bioavailability of a new chewable, buffered acetylsalicylic acid tablet formulation in comparison to a conventional plain tablet by Lücker, P W, Wetzelsberger, N, Schettler, T, Rogalla, K

“…The pharmacokinetics of acetylsalicylic acid (ASA) and its main metabolite salicylic acid (SA) following single dose administration of a new chewable, buffered…”
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Voglibose (AO-128) is an efficient alpha-glucosidase inhibitor and mobilizes the endogenous GLP-1 reserve by Göke, B, Fuder, H, Wieckhorst, G, Theiss, U, Stridde, E, Littke, T, Kleist, P, Arnold, R, Lücker, P W

“…The alpha-glucosidase inhibitor voglibose (AO-128) was designed to prevent rapid postprandial blood glucose rises in non-insulin-dependent diabetics. We…”
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Effect of buffering on pharmacokinetics of ketoprofen enantiomers in man by Fuder, H., Stiegler, S., Wetzelsberger, N., Wieckhorst, G., Lange, R., Lücker, P. W.

“…Aims Concomitant administration of magnesium hydroxide may affect the rate or extent of absorption of non‐steroidal anti‐inflammatory drugs. In order to find…”
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Influence of cholestyramine on the pharmacokinetics of cerivastatin by Mück, W, Ritter, W, Frey, R, Wetzelsberger, N, Lücker, P W, Kuhlmann, J

“…The possible influence of the bile acid sequestering agent cholestyramine, a basic comedication in hypercholesterolemic patients, on the pharmacokinetics of…”
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Compliance: one of the most important correlations in clinical pharmacology by Lücker, P W

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Iontophoresis--is there a future for clinical application? by Theiss, U, Kuhn, I, Lücker, P W

“…Transdermal application of drugs is a field of great importance in medical therapy. The application is painless and may be controlled at any time…”
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Pharmacodynamic effects of 3-day intravenous treatment with pantoprazole or ranitidine after 10 days of oral ranitidine by LEY, L. M, BECKER, A, LÜHMANN, R, SANDER, P, LÜCKER, P. W

“…Tachyphylaxis (drug tolerance) is an undesirable condition in drug therapy with histamine-2-receptor antagonists (H2RAs). The concept of overcoming…”
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Impedance cardiography--a reliable method for measuring cardiac function noninvasively by Venitz, J, Lücker, P W

“…The paper describes a new and further developed assessment for the measuring of cardiac function with impedance cardiography. The method is described in detail…”
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Concomitant administration of the α-glucosidase inhibitor voglibose (AO-128) does not alter the pharmacokinetics of glibenclamide by KLEIST, P, EHRLICH, A, SUZUKI, Y, TIMMER, W, WETZELSBERGER, N, LÜCKER, P. W, FUDER, H

“…Voglibose is a new and potent inhibitor of alpha-glucosidases used for treatment of diabetes mellitus. It increases gastro-intestinal motility and could thus…”
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