Search Results - "Lötjönen, Jyrki"

Automatically computed rating scales from MRI for patients with cognitive disorders by Koikkalainen, Juha R., Rhodius-Meester, Hanneke F. M., Frederiksen, Kristian S., Bruun, Marie, Hasselbalch, Steen G., Baroni, Marta, Mecocci, Patrizia, Vanninen, Ritva, Remes, Anne, Soininen, Hilkka, van Gils, Mark, van der Flier, Wiesje M., Scheltens, Philip, Barkhof, Frederik, Erkinjuntti, Timo, Lötjönen, Jyrki M. P.

“…Objectives The aims of this study were to examine whether visual MRI rating scales used in diagnostics of cognitive disorders can be estimated computationally…”
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Multi-template tensor-based morphometry: Application to analysis of Alzheimer's disease by Koikkalainen, Juha, Lötjönen, Jyrki, Thurfjell, Lennart, Rueckert, Daniel, Waldemar, Gunhild, Soininen, Hilkka

“…In this paper methods for using multiple templates in tensor-based morphometry (TBM) are presented and compared to the conventional single-template approach…”
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Fast and robust multi-atlas segmentation of brain magnetic resonance images by Lötjönen, Jyrki MP, Wolz, Robin, Koikkalainen, Juha R., Thurfjell, Lennart, Waldemar, Gunhild, Soininen, Hilkka, Rueckert, Daniel

“…We introduce an optimised pipeline for multi-atlas brain MRI segmentation. Both accuracy and speed of segmentation are considered. We study different…”
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Associations of cognitive reserve and psychological resilience with cognitive functioning in subjects with cerebral white matter hyperintensities by Arola, Anne, Laakso, Hanna M., Pitkänen, Johanna, Koikkalainen, Juha, Lötjönen, Jyrki, Korvenoja, Antti, Erkinjuntti, Timo, Melkas, Susanna, Jokinen, Hanna

“…Background and purpose Cerebral small vessel disease is characterized by progressive white matter hyperintensities (WMH) and cognitive decline. However,…”
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Differential diagnosis of neurodegenerative diseases using structural MRI data by Koikkalainen, Juha, Rhodius-Meester, Hanneke, Tolonen, Antti, Barkhof, Frederik, Tijms, Betty, Lemstra, Afina W, Tong, Tong, Guerrero, Ricardo, Schuh, Andreas, Ledig, Christian, Rueckert, Daniel, Soininen, Hilkka, Remes, Anne M, Waldemar, Gunhild, Hasselbalch, Steen, Mecocci, Patrizia, van der Flier, Wiesje, Lötjönen, Jyrki

“…Different neurodegenerative diseases can cause memory disorders and other cognitive impairments. The early detection and the stratification of patients…”
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Frontal white and gray matter abnormality in gambling disorder: A multimodal MRI study by Bellmunt-Gil, Albert, Vorobyev, Victor, Parkkola, Riitta, Lötjönen, Jyrki, Joutsa, Juho, Kaasinen, Valtteri

“…Changes in brain structural connections appear to be important in the pathophysiology of substance use disorders, but their role in behavioral addictions, such…”
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Computerized decision support is an effective approach to select memory clinic patients for amyloid-PET by Rhodius-Meester, Hanneke F M, van Maurik, Ingrid S, Collij, Lyduine E, van Gils, Aniek M, Koikkalainen, Juha, Tolonen, Antti, Pijnenburg, Yolande A L, Berkhof, Johannes, Barkhof, Frederik, van de Giessen, Elsmarieke, Lötjönen, Jyrki, van der Flier, Wiesje M

“…The use of amyloid-PET in dementia workup is upcoming. At the same time, amyloid-PET is costly and limitedly available. While the appropriate use criteria…”
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Brain volumes and cortical thickness on MRI in the Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability (FINGER) by Stephen, Ruth, Liu, Yawu, Ngandu, Tiia, Antikainen, Riitta, Hulkkonen, Juha, Koikkalainen, Juha, Kemppainen, Nina, Lötjönen, Jyrki, Levälahti, Esko, Parkkola, Riitta, Pippola, Pauliina, Rinne, Juha, Strandberg, Timo, Tuomilehto, Jaakko, Vanninen, Ritva, Kivipelto, Miia, Soininen, Hilkka, Solomon, Alina

“…The Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability (FINGER) was a multicenter randomized controlled trial that reported…”
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Robust whole-brain segmentation: Application to traumatic brain injury by Ledig, Christian, Heckemann, Rolf A., Hammers, Alexander, Lopez, Juan Carlos, Newcombe, Virginia F.J., Makropoulos, Antonios, Lötjönen, Jyrki, Menon, David K., Rueckert, Daniel

“…[Display omitted] •A robust and fully-automatic segmentation framework for MR brain scans is proposed.•A heterogeneous cohort of 125 scans of patients who had…”
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A novel CT-based automated analysis method provides comparable results with MRI in measuring brain atrophy and white matter lesions by Kaipainen, Aku L, Pitkänen, Johanna, Haapalinna, Fanni, Jääskeläinen, Olli, Jokinen, Hanna, Melkas, Susanna, Erkinjuntti, Timo, Vanninen, Ritva, Koivisto, Anne M, Lötjönen, Jyrki, Koikkalainen, Juha, Herukka, Sanna-Kaisa, Julkunen, Valtteri

“…Purpose Automated analysis of neuroimaging data is commonly based on magnetic resonance imaging (MRI), but sometimes the availability is limited or a patient…”
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The Association Between Distinct Frontal Brain Volumes and Behavioral Symptoms in Mild Cognitive Impairment, Alzheimer's Disease, and Frontotemporal Dementia by Cajanus, Antti, Solje, Eino, Koikkalainen, Juha, Lötjönen, Jyrki, Suhonen, Noora-Maria, Hallikainen, Ilona, Vanninen, Ritva, Hartikainen, Päivi, de Marco, Matteo, Venneri, Annalena, Soininen, Hilkka, Remes, Anne M., Hall, Anette

“…Our aim was to investigate the association between behavioral symptoms of agitation, disinhibition, irritability, elation, and aberrant motor behavior to…”
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Change in CAIDE Dementia Risk Score and Neuroimaging Biomarkers During a 2-Year Multidomain Lifestyle Randomized Controlled Trial: Results of a Post-Hoc Subgroup Analysis by Stephen, Ruth, Ngandu, Tiia, Liu, Yawu, Peltonen, Markku, Antikainen, Riitta, Kemppainen, Nina, Laatikainen, Tiina, Lötjönen, Jyrki, Rinne, Juha, Strandberg, Timo, Tuomilehto, Jaakko, Vanninen, Ritva, Soininen, Hilkka, Kivipelto, Miia, Solomon, Alina

“…Abstract The CAIDE (Cardiovascular Risk Factors, Aging and Dementia) Risk Score is a validated tool estimating dementia risk. It was previously associated with…”
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Regional brain morphometry in patients with traumatic brain injury based on acute- and chronic-phase magnetic resonance imaging by Ledig, Christian, Kamnitsas, Konstantinos, Koikkalainen, Juha, Posti, Jussi P, Takala, Riikka S K, Katila, Ari, Frantzén, Janek, Ala-Seppälä, Henna, Kyllönen, Anna, Maanpää, Henna-Riikka, Tallus, Jussi, Lötjönen, Jyrki, Glocker, Ben, Tenovuo, Olli, Rueckert, Daniel

“…Traumatic brain injury (TBI) is caused by a sudden external force and can be very heterogeneous in its manifestation. In this work, we analyse T1-weighted…”
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Nonlinear dimensionality reduction combining MR imaging with non-imaging information by Wolz, Robin, Aljabar, Paul, Hajnal, Joseph V., Lötjönen, Jyrki, Rueckert, Daniel

“…The top figure shows a 2D manifold embedding of images acquired from subjects with AD (squares) and healthy controls (circles) using pairwise image…”
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Metabolic Profiles Help Discriminate Mild Cognitive Impairment from Dementia Stage in Alzheimer's Disease by Jääskeläinen, Olli, Hall, Anette, Tiainen, Mika, van Gils, Mark, Lötjönen, Jyrki, Kangas, Antti J, Helisalmi, Seppo, Pikkarainen, Maria, Hallikainen, Merja, Koivisto, Anne, Hartikainen, Päivi, Hiltunen, Mikko, Ala-Korpela, Mika, Soininen, Pasi, Soininen, Hilkka, Herukka, Sanna-Kaisa

“…Accurate differentiation between neurodegenerative diseases is developing quickly and has reached an effective level in disease recognition. However, there has…”
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Detecting frontotemporal dementia syndromes using MRI biomarkers by Bruun, Marie, Koikkalainen, Juha, Rhodius-Meester, Hanneke F M, Baroni, Marta, Gjerum, Le, van Gils, Mark, Soininen, Hilkka, Remes, Anne M, Hartikainen, Päivi, Waldemar, Gunhild, Mecocci, Patrizia, Barkhof, Frederik, Pijnenburg, Yolande, van der Flier, Wiesje M, Hasselbalch, Steen G, Lötjönen, Jyrki, Frederiksen, Kristian S

“…Diagnosing frontotemporal dementia may be challenging. New methods for analysis of regional brain atrophy patterns on magnetic resonance imaging (MRI) could…”
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Blood biomarkers of neurodegeneration associate differently with amyloid deposition, medial temporal atrophy, and cerebrovascular changes in APOE ε4-enriched cognitively unimpaired elderly by Koivumäki, Mikko, Ekblad, Laura, Lantero-Rodriguez, Juan, Ashton, Nicholas J, Karikari, Thomas K, Helin, Semi, Parkkola, Riitta, Lötjönen, Jyrki, Zetterberg, Henrik, Blennow, Kaj, Rinne, Juha O, Snellman, Anniina

“…Alzheimer's disease (AD) is characterized by the accumulation of amyloid-β (Aβ) plaques, neurofibrillary tau tangles, and neurodegeneration in the brain…”
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Association between Deep Gray Matter Changes and Neurocognitive Function in Mild Cognitive Impairment and Alzheimer's Disease: A Tensor-Based Morphometric MRI Study by Tuokkola, Terhi, Karrasch, Mira, Koikkalainen, Juha, Parkkola, Riitta, Lötjönen, Jyrki, Löyttyniemi, Eliisa, Hurme, Saija, Rinne, Juha Olavi

“…Atrophy of the deep gray matter (DGM) has been associated with a risk of conversion from mild cognitive impairment (MCI) to Alzheimer's disease (AD) and the…”
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Selection of memory clinic patients for CSF biomarker assessment can be restricted to a quarter of cases by using computerized decision support, without compromising diagnostic accuracy by Rhodius-Meester, Hanneke F M, van Maurik, Ingrid S, Koikkalainen, Juha, Tolonen, Antti, Frederiksen, Kristian S, Hasselbalch, Steen G, Soininen, Hilkka, Herukka, Sanna-Kaisa, Remes, Anne M, Teunissen, Charlotte E, Barkhof, Frederik, Pijnenburg, Yolande A L, Scheltens, Philip, Lötjönen, Jyrki, van der Flier, Wiesje M

“…An accurate and timely diagnosis for Alzheimer's disease (AD) is important, both for care and research. The current diagnostic criteria allow the use of CSF…”
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Prediction models for dementia and neuropathology in the oldest old: the Vantaa 85+ cohort study by Hall, Anette, Pekkala, Timo, Polvikoski, Tuomo, van Gils, Mark, Kivipelto, Miia, Lötjönen, Jyrki, Mattila, Jussi, Kero, Mia, Myllykangas, Liisa, Mäkelä, Mira, Oinas, Minna, Paetau, Anders, Soininen, Hilkka, Tanskanen, Maarit, Solomon, Alina

“…We developed multifactorial models for predicting incident dementia and brain pathology in the oldest old using the Vantaa 85+ cohort. We included participants…”
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