Search Results - "Löffler, K."

A novel siRNA-lipoplex technology for RNA interference in the mouse vascular endothelium by SANTEL, A, ALEKU, M, GIESE, K, KLIPPEL, A, KAUFMANN, J, KEIL, O, ENDRUSCHAT, J, ESCHE, V, FISCH, G, DAMES, S, LÖFFLER, K, FECHTNER, M, ARNOLD, W

“…For the application of RNA interference (RNAi) in vivo the functional delivery of short interfering RNAs (siRNAs) is still the major obstacle. Therefore,…”
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Learning from Alfred Wegener’s pioneering field observations in West Greenland after a century of climate change by Abermann, J., Vandecrux, B., Scher, S., Löffler, K., Schalamon, F., Trügler, A., Fausto, R., Schöner, W.

“…The cryosphere in Greenland is currently undergoing strong changes. While remote sensing improves our understanding of spatial and temporal changes across…”
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RNA interference in the mouse vascular endothelium by systemic administration of siRNA-lipoplexes for cancer therapy by SANTEL, A, ALEKU, M, DAMES, S, ARNOLD, W, GIESE, K, KLIPPEL, A, KAUFMANN, J, KEIL, O, ENDRUSCHAT, J, ESCHE, V., DURIEUX, B, LÖFFLER, K, FECHTNER, M, RÖHL, T, FISCH, G

“…RNA interference (RNAi) entails the potential for novel therapeutic strategies through the silencing of disease-causing genes in vivo. However, recent studies…”
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Essential tremor and cerebellar dysfunction Clinical and kinematic analysis of intention tremor by Deuschl, G., Wenzelburger, R., Löffler, K., Raethjen, J., Stolze, H.

“…The cerebellum is assumed to play a major role in the pathophysiology of essential tremor (ET). As intention tremor is considered one of the classical features…”
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Immunoreactivity against tau, amyloid precursor protein, and beta- amyloid in the human retina by Loffler, KU, Edward, DP, Tso, MO

“…Increased immunoreactivity (IR) of beta-amyloid and the amyloid-associated proteins tau and amyloid precursor protein (APP) in the brain have been linked to…”
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Real-time gripping detection for a mechanically actuated microgripper by Blideran, M.M., Fleischer, M., Grauvogel, F., Löffler, K., Langer, M.G., Kern, D.P.

“…The possibility of controlled gripping during micromanipulation procedures is widely desired in the fields of microbiology and microassembly. For achieving it,…”
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Kinetic tremor in a reach-to-grasp movement in Parkinson's disease by Wenzelburger, R., Raethjen, J., Löffler, K., Stolze, H., Illert, M., Deuschl, G.

“…The aim of this study was to quantify the tremor of the hand during a natural movement (kinetic tremor) in tremor‐dominant parkinsonian patients (n = 13). We…”
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Defizite der ergotherapeutischen Routineversorgung bei rheumatischen Erkrankungen: Ergebnisse einer Auswertung der RheumaDat-Panel-Befragung by Thieme, H., Löffler, K., Borgetto, B.

“…Zusammenfassung Hintergrund Ziel der vorliegenden Arbeit ist die Darstellung der Versorgungshäufigkeit und möglicher Determinanten der ergotherapeutischen…”
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Sensors and control concept of a biped robot by Loffler, K., Gienger, M., Pfeiffer, F., Ulbrich, H.

“…The biped robot "Johnnie" is designed to achieve a dynamically stable gait pattern, allowing for high walking velocities. Very accurate and fast sensors were…”
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Cation permeation and blockade of ROMK1, a cloned renal potassium channel by Löffler, K, Hunter, M

“…ROMK1 is an inwardly rectifying K+ channel cloned from the outer medulla of rat kidney. We have determined the permeation and blocking characteristics for…”
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Sensors and Control Concept of Walking 'Johnnie' by Loffler, K, Gienger, M, Pfeiffer, F

“…One key problem to achieve a dynamically stable walking motion with biped robots is to measure and control the actual state of the robot with respect to its…”
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How effective is AAL? Results from an RCT among older persons in Austria by Schmidt, L, Majcen, K, Löffler, K, Schuster, E, Augustin, T, Murg, S, König, C, Steiner, J

“…Abstract Background Many older people wish to remain in their own environment for as long as possible; an aim shared by the wider community. Here the results…”
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Lack of augmentation of tumor spectrum or severity in dual heterozygous Men1 and Rb1 knockout mice by LOFFLER, K. A, BIONDI, C. A, HAYWARD, N. K, GARTSIDE, M. G, SEREWKO-AURET, M. M, DUNCAN, R, TONKS, I. D, MOULD, A. W, WARING, P, MULLER, H. K, KAY, G. F

“…To identify possible genetic interactions between the mechanisms of tumor suppression of menin and pRb, we intercrossed mice with targeted deletions of Men1…”
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Flash Evaporation in Cyclones by Loffler, M K

“…Flash processes have been investigated several times [1–4]. This study focuses on the flash process taking place in a cyclone. The separated and extracted…”
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Emotional dysfunctions in neurodegenerative diseases by Löffler, Leonie A.K., Radke, Sina, Morawetz, Carmen, Derntl, Birgit

“…ABSTRACT Neurodegenerative diseases are characterized primarily by motor signs but are also accompanied by emotional disturbances. Because of the limited…”
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Blepharitis - When to Perform Surgery? by Herwig, M C, Löffler, K U

“…Meibomian gland dysfunction/blepharitis is usually a harmless inflammatory process of the lid margin. However, it can be the first sign of a malignant lesion…”
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Morphologic Corneal Changes after Crosslinking for Keratoconus by Müller, P L, Löffler, K U, Kohlhaas, M, Holz, F G, Herwig-Carl, M C

“…Keratoconus is a relatively common (1 : 2000) bilateral disease leading to a change in biochemical and biomechanical corneal structure as well as thinning and…”
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Short-term hemodynamic, anti-ischemic, and antianginal effects of Pirsidomine, a new sydnonimine by STENGELE, E, RUF, G, JÄHNCHEN, E, TRENK, D, LÖFFLER, K, SCHULZ, W, ROSKAMM, H

“…Pirsidomine is a new sydnonimine compound in clinical development. As a prodrug, it is transformed into a nitric oxide-releasing metabolite in vivo. In animal…”
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Pharmacokinetics and pharmacodynamics of ramipril and piretanide administered alone and in combination by Ruf, G, Gera, S, Luus, H G, Trenk, D, de la Rey, N, Löffler, K, Schulz, W, Jähnchen, E

“…The pharmacokinetics and pharmacodynamics of single oral doses of 5 mg ramipril and 6 mg piretanide administered separately and in combination were determined…”
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Molecular imaging system for possible prediction of active retinopathy in patients with Diabetes mellitus by Golubnitschaja, O, Jaksche, A, Moenkemann, H, Yeghiazaryan, K, Karl, S E, Trog, D, Schild, H H, Löffler, K U

“…The deposition of advanced glycation end products is enhanced in Diabetes mellitus (DM) and has been linked to diabetic complications such as a microvascular…”
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