Search Results - "Löbrich, M"

DNA double-strand breaks: their cellular and clinical impact? by Jeggo, P A, Löbrich, M

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Effect of CT scan protocols on x-ray-induced DNA double-strand breaks in blood lymphocytes of patients undergoing coronary CT angiography by Kuefner, M. A., Grudzenski, S., Hamann, J., Achenbach, S., Lell, Michael, Anders, K., Schwab, S. A., Häberle, L., Löbrich, M., Uder, M.

“…Aims To compare in vivo DNA lesions induced during helical and sequential coronary computed tomography angiography (CTA) and to evaluate the effect of CT…”
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Radiation-induced genomic rearrangements formed by nonhomologous end-joining of DNA double-strand breaks by ROTHKAMM, Kai, KÜHNE, Martin, JEGGO, Penny A, LÖBRICH, Markus

“…Two major pathways for repairing DNA double-strand breaks (DSBs) have been identified in mammalian cells, nonhomologous end-joining (NHEJ) and homologous…”
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No dose-dependence of DNA double-strand break misrejoining following α-particle irradiation by Kühne, K. Rothkamm, M. Löbrich, M.

“…Purpose : To investigate whether an explanation for the high effectiveness of densely ionizing radiation with regard to complex biological endpoints can be…”
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A review of dsb induction data for varying quality radiations by PRISE, K. M.

“…Purpose: This short review summarizes the data obtained with various techniques for measuring the yields of double strand breaks (dsb) produced by particle…”
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Joining of correct and incorrect DNA double-strand break ends in normal human and ataxia telangiectasia fibroblasts by Löbrich, Markus, Kühne, Martin, Wetzel, Jana, Rothkamm, Kai

“…Chromosomal aberrations are believed to result from the incorrect joining of DNA double‐strand breaks (DSBs). In an attempt to investigate induction and…”
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Physical and Biological Parameters Affecting DNA Double Strand Break Misrejoining in Mammalian Cells by Kühne, M., Rothkamm, K., Löbrich, M.

“…In an attempt to investigate the effect of radiation quality, dose and specific repair pathways on correct and erroneous rejoining of DNA double strand breaks…”
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Induction and repair of DNA double-strand breaks in human fibroblasts after particle irradiation by Lobrich, M

“…Two assay were employed to study the induction and repair of DNA double-strand breaks (dsbs) in normal human fibroblasts after exposure to particle radiation…”
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No dose-dependence of DNA double-strand break misrejoining following -particle irradiation by Kühne, K. Rothkamm, M. Löbrich, M.

“…Purpose : To investigate whether an explanation for the high effectiveness of densely ionizing radiation with regard to complex biological endpoints can be…”
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DNA double-strand break measurement in mammalian cells by pulsed-field gel electrophoresis: an approach using restriction enzymes and gene probing by Löbrich, M, Ikpeme, S, Kiefer, J

“…DNA samples prepared from human SP3 cells, which had been exposed to various doses of X-ray, were treated with NotI restriction endonuclease before being run…”
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Non-random distribution of DNA double-strand breaks induced by particle irradiation by Löbrich, M, Cooper, P K, Rydberg, B

“…Induction of DNA double-strand breaks (dsbs) in mammalian cells is dependent on the spatial distribution of energy deposition from the ionizing radiation. For…”
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Induction and Repair of DNA Damage in Human Cells at Different Stages of Differentiation by A. Tabocchini, M., Belli, M., Campa, A., Löbrich, M., Sapora, O., Simone, G., Stenerlöw (INVITED), B.

“…Use of cellular systems capable of undergoing in vitro differentiation can give useful information on the basic mechanisms of cellular radiation sensitivity…”
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Repair of X-Ray-Induced DNA Double-Strand Breaks in Specific Not I Restriction Fragments in Human Fibroblasts: Joining of Correct and Incorrect Ends by Lobrich, M., Rydberg, B., Cooper, P. K., Chatterjee, A.

“…An assay that allows measurement of absolute induction frequencies for DNA double-strand breaks (dsbs) in defined regions of the genome and that quantitates…”
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Heavy ion-induced DNA double-strand breaks with yeast as a model system by Ikpeme, S, Löbrich, M, Akpa, T, Schneider, E, Kiefer, J

“…Cells of diploid yeast, Saccharomyces cerevisiae, were exposed to a variety of energetic heavy ions (provided by the UNILAC facility at the Gesellschaft für…”
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Misrejoining of DNA double-strand breaks in primary and transformed human and rodent cells: a comparison between the HPRT region and other genomic locations by Rothkamm, Kai, Löbrich, Markus

“…Many studies of radiation response and mutagenesis have been carried out with transformed human or rodent cell lines. To study whether the transfer of results…”
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Joining of Correct and Incorrect DNA Ends at Double-Strand Breaks Produced by High-Linear Energy Transfer Radiation in Human Fibroblasts by Löbrich, Markus, Cooper, Priscilla K., Rydberg, Björn

“…DNA double-strand breaks (DSBs) were measured within a 3.2-Mbp NotI fragment on chromosome 21 of cells of a normal human fibroblast cell line. Correct…”
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Evidence for a Lack of DNA Double-Strand Break Repair in Human Cells Exposed to Very Low X-Ray Doses by Rothkamm, Kai, Löbrich, Markus

“…DNA double-strand breaks (DSBs) are generally accepted to be the most biologically significant lesion by which ionizing radiation causes cancer and hereditary…”
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X-ray-induced DNA double-strand breaks after angiographic examinations of different anatomic regions by Kuefner, M A, Grudzenski, S, Schwab, S A, Azoulay, S, Heckmann, M, Heinrich, M C, Lobrich, M, Uder, M

“…The aim of this study was to investigate DNA double-strand breaks (DSBs) in blood lymphocytes as markers of the biological radiation effects in angiography…”
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DNA Double-Strand Breaks Induced by High-Energy Neon and Iron Ions in Human Fibroblasts. I. Pulsed-Field Gel Electrophoresis Method by Rydberg, Björn, Löbrich, Markus, Cooper, Priscilla K.

“…The relative effectiveness of high-energy neon and iron ions for the production of DNA double-strand breaks was measured in one transformed and one…”
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Pathways of DNA Double-Strand Break Repair during the Mammalian Cell Cycle by Rothkamm, K, Krueger, I, Thompson, L H, Loebrich, M

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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