Search Results - "López de Las Hazas, María‐Carmen"

Eating microRNAs: pharmacological opportunities for cross‐kingdom regulation and implications in host gene and gut microbiota modulation by Pozo‐Acebo, Lorena, López de las Hazas, María‐Carmen, Margollés, Abelardo, Dávalos, Alberto, García‐Ruiz, Almudena

“…Cross‐kingdom communication via non‐coding RNAs is a recent discovery. Exogenous microRNAs (exog‐miRNAs) mainly enter the host via the diet. Generally…”
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Hydroxytyrosol Induces Dyslipidemia in an ApoB100 Humanized Mouse Model by López de las Hazas, María‐Carmen, Saz‐Lara, Andrea, Cedó, Lídia, Crespo, María Carmen, Tomé‐Carneiro, João, Chapado, Luis A., Macià, Alba, Visioli, Francesco, Escola‐Gil, Joan C., Dávalos, Alberto

“…Scope Extra virgin olive oil has numerous cardiopreventive effects, largely due to its high content of (poly)phenols such as hydroxytyrosol (HT). However, some…”
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The emergent role of mitochondrial RNA modifications in metabolic alterations by Boughanem, Hatim, Böttcher, Yvonne, Tomé‐Carneiro, João, López de las Hazas, María‐Carmen, Dávalos, Alberto, Cayir, Akin, Macias‐González, Manuel

“…Mitochondrial epitranscriptomics refers to the modifications occurring in all the different RNA types of mitochondria. Although the number of mitochondrial RNA…”
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Customized Dietary Intervention Avoids Unintentional Weight Loss and Modulates Circulating miRNAs Footprint in Huntington's Disease by Aganzo, Miguel, Montojo, María‐Teresa, López de Las Hazas, María‐Carmen, Martínez‐Descals, Asunción, Ricote‐Vila, Marta, Sanz, Raúl, González‐Peralta, Irene, Martín‐Hernández, Roberto, Dios, Olaya, Garcés, Carmen, Galdón, Alba, Lorenzo, Óscar, Tomás‐Zapico, Cristina, Dávalos, Alberto, Vázquez, Clotilde, González, Nieves

“…Scope Huntington's disease (HD) is a rare progressive neurodegenerative disorder of genetic origin, with no definitive treatment. Unintentional weight loss…”
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An overview of the pharmacology of olive oil and its active ingredients by Visioli, Francesco, Davalos, Alberto, López de las Hazas, María‐Carmen, Crespo, María Carmen, Tomé‐Carneiro, Joao

“…In addition to providing sensory stimuli, usually taste, smell and sight, olive oil contains a range of minor components, mostly phenolic in nature. These…”
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Milk-Derived Exosomes as Nanocarriers to Deliver Curcumin and Resveratrol in Breast Tissue and Enhance Their Anticancer Activity by González-Sarrías, Antonio, Iglesias-Aguirre, Carlos E, Cortés-Martín, Adrián, Vallejo, Fernando, Cattivelli, Alice, Del Pozo-Acebo, Lorena, Del Saz, Andrea, López de Las Hazas, María Carmen, Dávalos, Alberto, Espín, Juan Carlos

“…Dietary (poly)phenols are extensively metabolized, limiting their anticancer activity. Exosomes (EXOs) are extracellular vesicles that could protect…”
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Untoward Effects of Micro- and Nanoplastics: An Expert Review of Their Biological Impact and Epigenetic Effects by López de las Hazas, María-Carmen, Boughanem, Hatim, Dávalos, Alberto

“…The production of plastic has dramatically increased in the last 50 y. Because of their stability and durability, plastics are ubiquitously incorporated in…”
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Exploring the Colonic Metabolism of Grape and Strawberry Anthocyanins and Their in Vitro Apoptotic Effects in HT-29 Colon Cancer Cells by López de las Hazas, María-Carmen, Mosele, Juana I, Macià, Alba, Ludwig, Iziar A, Motilva, María-José

“…Beneficial properties attributed to the intake of fruit and red wine have been associated with the presence of significant amounts of anthocyanins. However,…”
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Nutri-Epigenetic Effects of Phenolic Compounds from Extra Virgin Olive Oil: A Systematic Review by del Saz-Lara, Andrea, López de las Hazas, María-Carmen, Visioli, Francesco, Dávalos, Alberto

“…Dietary components can induce epigenetic changes through DNA methylation, histone modification, and regulation of microRNAs (miRNAs). Studies of diet-induced…”
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Therapeutic potential of plant-derived extracellular vesicles as nanocarriers for exogenous miRNAs by López de las Hazas, María-Carmen, Tomé-Carneiro, Joao, del Pozo-Acebo, Lorena, del Saz-Lara, Andrea, Chapado, Luis A., Balaguer, Livia, Rojo, Enrique, Espín, Juan Carlos, Crespo, Carmen, Moreno, Diego A., García-Viguera, Cristina, Ordovás, José M., Visioli, Francesco, Dávalos, Alberto

“…Cell-to-cell communication strategies include extracellular vesicles (EVs) in plants and animals. The bioactive molecules in a diet rich in vegetables and…”
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Connection between miRNA Mediation and the Bioactive Effects of Broccoli (Brassica oleracea var. italica): Exogenous miRNA Resistance to Food Processing and GI Digestion by Chapado, Luis A, Martín-Hernández, Roberto, Hernández de la Red, Silvia, Tomé-Carneiro, João, Gil-Zamorano, Judit, Ruiz-Roso, María Belén, del Saz, Andrea, Crespo, M. Carmen, del Pozo-Acebo, Lorena, Arantes Ferreira Peres, Wilza, de la Peña, Gema, López de las Hazas, María-Carmen, Dávalos, Alberto

“…Broccoli (Brassica oleracea var. italica) and its bioactive compounds are associated with beneficial health effects, which might be enabled, at least in part,…”
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Exosome-Containing Extracellular Vesicles Contribute to the Transport of Resveratrol Metabolites in the Bloodstream: A Human Pharmacokinetic Study by Iglesias-Aguirre, Carlos Eduardo, Ávila-Gálvez, María Ángeles, López de Las Hazas, María-Carmen, Dávalos, Alberto, Espín, Juan Carlos

“…Exosomes are extracellular vesicles (EVs) that regulate intercellular signaling by transferring small RNAs, proteins, nucleic acids, lipids, and other…”
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Response to: Letter to the editor regarding “Dietary bovine milk miRNAs transported in extracellular vesicles are partially stable during GI digestion, are bioavailable and reach target tissues but need a minimum dose to impact on gene expression” by López de las Hazas, María-Carmen, del Pozo-Acebo, Lorena, Dávalos, Alberto

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Differential absorption and metabolism of hydroxytyrosol and its precursors oleuropein and secoiridoids by López de las Hazas, María-Carmen, Piñol, Carme, Macià, Alba, Romero, María-Paz, Pedret, Anna, Solà, Rosa, Rubió, Laura, Motilva, Maria-José

“…•The maximum efficiency in the bioavailability of HT was observed after OLE.•This was related to the higher stability of OLE under digestion conditions.•The…”
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Microbiota dysbiosis caused by dietetic patterns as a promoter of Alzheimer's disease through metabolic syndrome mechanisms by Navalón-Monllor, Víctor, Soriano-Romaní, Laura, Silva, Mariana, de Las Hazas, María-Carmen López, Hernando-Quintana, Natalia, Suárez Diéguez, Teodoro, Esteve, Pere Morell, Nieto, Juan Antonio

“…Microbiota dysbiosis and metabolic syndrome, consequences of a non-adequate diet, generate a feedback pathogenic state implicated in Alzheimer's disease…”
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Impact of Long-Term Supplementation with Fish Oil in Individuals with Non-Alcoholic Fatty Liver Disease: A Double Blind Randomized Placebo Controlled Clinical Trial by Cansanção, Kátia, Citelli, Marta, Carvalho Leite, Nathalie, López de Las Hazas, María-Carmen, Dávalos, Alberto, Tavares do Carmo, Maria das Graças, Peres, Wilza Arantes Ferreira

“…Non-alcoholic fatty liver disease (NAFLD) is a chronic disease affecting up to 25% of the population worldwide. n-3 long-chain polyunsaturated fatty acids (n-3…”
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One-year dietary supplementation with walnuts modifies exosomal miRNA in elderly subjects by López de las Hazas, María-Carmen, Gil-Zamorano, Judit, Cofán, Montserrat, Mantilla-Escalante, Diana C., Garcia-Ruiz, Almudena, del Pozo-Acebo, Lorena, Pastor, Oscar, Yañez-Mo, María, Mazzeo, Carla, Serra-Mir, Mercè, Doménech, Monica, Valls-Pedret, Cinta, Rajaram, Sujatha, Sabaté, Joan, Ros, Emilio, Sala-Vila, Aleix, Dávalos, Alberto

“…Purpose Epidemiological studies and clinical trials support the association of nut consumption with a lower risk of prevalent non-communicable diseases,…”
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Brain uptake of hydroxytyrosol and its main circulating metabolites: Protective potential in neuronal cells by López de las Hazas, María-Carmen, Godinho-Pereira, Joana, Macià, Alba, Almeida, A. Filipa, Ventura, M. Rita, Motilva, Maria-José, Santos, Cláudia N.

“…[Display omitted] •Dietary intake of olive oil phenols and their metabolites reach the brain, where they are accumulated.•Hydroxytyrosol sulphate and…”
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Postprandial Circulating miRNAs in Response to a Dietary Fat Challenge by Mantilla-Escalante, Diana C, López de Las Hazas, María-Carmen, Gil-Zamorano, Judit, Del Pozo-Acebo, Lorena, Crespo, M Carmen, Martín-Hernández, Roberto, Del Saz, Andrea, Tomé-Carneiro, Joao, Cardona, Fernando, Cornejo-Pareja, Isabel, García-Ruiz, Almudena, Briand, Olivier, Lasunción, Miguel A, Visioli, Francesco, Dávalos, Alberto

“…Postprandial lipemia has many physiopathological effects, some of which increase the risk of cardiovascular disease. MicroRNAs (miRNAs) can be found in almost…”
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Exosomes transport trace amounts of (poly)phenols by Arola-Arnal, Anna, López de Las Hazas, María-Carmen, Iglesias-Carres, Lisard, Mantilla-Escalante, Diana C, Suárez, Manuel, Busto, Rebeca, Visioli, Francesco, Bladé, Cinta, Dávalos, Alberto

“…(Poly)phenols have varied biological activities that may account for the beneficial effects of fruits and vegetables as part of a healthy diet. Although their…”
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