Search Results - "López Rodríguez, Ana Belén"

Molecular Characterization of a Novel N-Acetylneuraminate Lyase from Lactobacillus plantarum WCFS1 by Guiomar Sánchez-Carrón, María Inmaculada García-García, Ana Belén López-Rodríguez, Sofía Jiménez-García, Agustín Sola-Carvajal, Francisco García-Carmona, Álvaro Sánchez-Ferrer

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Synthesis and Pharmacological Evaluation of New N‑Sulfonylureas as NLRP3 Inflammasome Inhibitors: Identification of a Hit Compound to Treat Gout by Narros-Fernández, Paloma, Chioua, Mourad, Petcu, Sonia A, Diez-Iriepa, Daniel, Cerrada-Gálvez, Laura, Decouty-Pérez, Céline, Palomino-Antolín, Alejandra, Ramos, Eva, Farré-Alins, Víctor, López-Rodríguez, Ana Belén, Romero, Alejandro, Marco-Contelles, José, Egea, Javier

“…NLRP3 is involved in the pathophysiology of several inflammatory diseases. Therefore, there is high current interest in the clinical development of new NLRP3…”
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Oxidative damage in reperfusion after stroke: ferroptosis and the role of the mitochondrial sodium/calcium exchanger NCLX by Delgado-Martín, Susana, Hugo, Martín, López-Rodríguez, Ana Belén, De Los Ríos-Salgado, Cristóbal, Martínez-Ruiz, Antonio

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New roles of mitochondrial Na+ import by the Na+/Ca2+ exchanger NCLX: activation of the HIF pathway and of the NLRP3 inflammasome by Choya-Foces, Carmen, Narros-Fernández, Paloma, Hernansanz-Agustín, Pablo, Decouty, Céline, López-Rodríguez, Ana Belén, Egea, Javier, Martínez-Ruiz, Antonio

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New roles of mitochondrial Na+ import by the Na+/Ca2+ exchanger NCLX: activation of the HIF pathway and of the NLRP3 inflammasome by Choya-Foces, Carmen, Narros-Fernández, Paloma, Hernansanz-Agustín, Pablo, Decouty-Pérez, Céline, López-Rodríguez, Ana Belén, Egea, Javier, Martínez-Ruiz, Antonio

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Time‐dependent dual effect of NLRP3 inflammasome in brain ischaemia by Palomino‐Antolin, Alejandra, Narros‐Fernández, Paloma, Farré‐Alins, Víctor, Sevilla‐Montero, Javier, Decouty‐Pérez, Celine, Lopez‐Rodriguez, Ana Belen, Fernández, Nuria, Monge, Luis, Casas, Ana I., Calzada, María José, Egea, Javier

“…Background Inflammasomes are cytosolic multiprotein complexes which, upon assembly, activate the maturation and secretion of the inflammatory cytokines IL‐1β…”
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The Endocannabinoid System as Pharmacological Target Derived from Its CNS Role in Energy Homeostasis and Reward. Applications in Eating Disorders and Addiction by Viveros, Maria-Paz, Bermúdez-Silva, Francisco-Javier, Lopez-Rodriguez, Ana-Belén, Wagner, Edward J

“…The endocannabinoid system (ECS) has been implicated in many physiological functions, including the regulation of appetite, food intake and energy balance, a…”
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TLR4 pathway impairs synaptic number and cerebrovascular functions through astrocyte activation following traumatic brain injury by Rosa, Juliana M., Farré‐Alins, Víctor, Ortega, María Cristina, Navarrete, Marta, Lopez‐Rodriguez, Ana Belen, Palomino‐Antolín, Alejandra, Fernández‐López, Elena, Vila‐del Sol, Virginia, Decouty, Céline, Narros‐Fernández, Paloma, Clemente, Diego, Egea, Javier

“…Background and Purpose Activation of astrocytes contributes to synaptic remodelling, tissue repair and neuronal survival following traumatic brain injury…”
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Chronic neurodegeneration induces type I interferon synthesis via STING, shaping microglial phenotype and accelerating disease progression by Nazmi, Arshed, Field, Robert H., Griffin, Eadaoin W., Haugh, Orla, Hennessy, Edel, Cox, Donal, Reis, Renata, Tortorelli, Lucas, Murray, Carol L., Lopez‐Rodriguez, Ana Belen, Jin, Lei, Lavelle, Ed C., Dunne, Aisling, Cunningham, Colm

“…Type I interferons (IFN‐I) are the principal antiviral molecules of the innate immune system and can be made by most cell types, including central nervous…”
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Sex‐dependent long‐term effects of adolescent exposure to THC and/or MDMA on neuroinflammation and serotoninergic and cannabinoid systems in rats by Lopez‐Rodriguez, Ana Belen, Llorente‐Berzal, Alvaro, Garcia‐Segura, Luis M, Viveros, Maria‐Paz

“…Background and Purpose Many young people consume ecstasy as a recreational drug and often in combination with cannabis. In this study, we aimed to mimic human…”
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Blockage of neonatal leptin signaling induces changes in the hypothalamus associated with delayed pubertal onset and modifications in neuropeptide expression during adulthood in male rats by Mela, Virginia, Jimenez, Sara, Freire-Regatillo, Alejandra, Barrios, Vicente, Marco, Eva-María, Lopez-Rodriguez, Ana-Belén, Argente, Jesús, Viveros, María-Paz, Chowen, Julie A.

“…•Blockage of leptin signaling neonatally delays pubertal onset in male rats.•Neonatal leptin antagonism increases serum leptin, insulin and triglycerides in…”
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Systemic TNF-α produces acute cognitive dysfunction and exaggerated sickness behavior when superimposed upon progressive neurodegeneration by Hennessy, Edel, Gormley, Shane, Belen Lopez-Rodriguez, Ana, Murray, Caoimhe, Murray, Carol, Cunningham, Colm

“…Graphical abstract…”
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Astrocytes: Heterogeneous and Dynamic Phenotypes in Neurodegeneration and Innate Immunity by Cunningham, Colm, Dunne, Aisling, Lopez-Rodriguez, Ana Belen

“…Astrocytes are the most numerous cell type in the brain and perform several essential functions in supporting neuronal metabolism and actively participating in…”
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Acute systemic inflammation exacerbates neuroinflammation in Alzheimer's disease: IL‐1β drives amplified responses in primed astrocytes and neuronal network dysfunction by Lopez‐Rodriguez, Ana Belen, Hennessy, Edel, Murray, Carol L., Nazmi, Arshed, Delaney, Hugh J., Healy, Dáire, Fagan, Steven G., Rooney, Michael, Stewart, Erika, Lewis, Anouchka, Barra, Niamh, Scarry, Philip, Riggs‐Miller, Louise, Boche, Delphine, Cunningham, Mark O., Cunningham, Colm

“…Neuroinflammation contributes to Alzheimer's disease (AD) progression. Secondary inflammatory insults trigger delirium and can accelerate cognitive decline…”
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Acute Inflammation Alters Brain Energy Metabolism in Mice and Humans: Role in Suppressed Spontaneous Activity, Impaired Cognition, and Delirium by Kealy, John, Murray, Carol, Griffin, Eadaoin W, Lopez-Rodriguez, Ana Belen, Healy, Dáire, Tortorelli, Lucas Silva, Lowry, John P, Watne, Leiv Otto, Cunningham, Colm

“…Systemic infection triggers a spectrum of metabolic and behavioral changes, collectively termed sickness behavior, which while adaptive, can affect mood and…”
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Bath salts and polyconsumption: in search of drug-drug interactions by Lopez-Rodriguez, Ana Belen, Viveros, Maria-Paz

“…Background and rationale Polydrug use is a widespread phenomenon, especially among adolescents and young adults. Synthetic cathinones are frequently consumed…”
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A comparative, developmental, and clinical perspective of neurobehavioral sexual dimorphisms by Viveros, Maria-Paz, Mendrek, Adriana, Paus, Tomáš, López-Rodríguez, Ana Belén, Marco, Eva Maria, Yehuda, Rachel, Cohen, Hagit, Lehrner, Amy, Wagner, Edward J

“…Women and men differ in a wide variety of behavioral traits and in their vulnerability to developing certain mental disorders. This review endeavors to explore…”
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Changes in cannabinoid receptors, aquaporin 4 and vimentin expression after traumatic brain injury in adolescent male mice. Association with edema and neurological deficit by Lopez-Rodriguez, Ana Belen, Acaz-Fonseca, Estefania, Viveros, Maria-Paz, Garcia-Segura, Luis M

“…Traumatic brain injury (TBI) incidence rises during adolescence because during this critical neurodevelopmental period some risky behaviors increase. The…”
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Profiling Neuroactive Steroid Levels After Traumatic Brain Injury in Male Mice by Lopez-Rodriguez, Ana Belen, Acaz-Fonseca, Estefania, Spezzano, Roberto, Giatti, Silvia, Caruso, Donatella, Viveros, Maria-Paz, Melcangi, Roberto C, Garcia-Segura, Luis M

“…The incidence of traumatic brain injuries (TBIs) in humans has rapidly increased in the last ten years. The most common causes are falls and car accidents…”
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Correlation of brain levels of progesterone and dehydroepiandrosterone with neurological recovery after traumatic brain injury in female mice by Lopez-Rodriguez, Ana Belen, Acaz-Fonseca, Estefania, Giatti, Silvia, Caruso, Donatella, Viveros, Maria-Paz, Melcangi, Roberto C, Garcia-Segura, Luis M

“…Highlights • Neuroactive steroid levels change in the brain after TBI. • Brain and plasma steroid levels vary differently and independently after TBI. • Brain…”
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