Search Results - "López Muñoz, A."
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Mind the Curve: Dose-Response Fitting Biases the Synergy Scores across Software Used for Chemotherapy Combination Studies
Published in International journal of molecular sciences (03-06-2023)“…Drug combinations are increasingly studied in the field of anticancer agents. Mathematical models, such as Loewe, Bliss, and HSA, are used to interpret drug…”
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Reprogramming human B cells into induced pluripotent stem cells and its enhancement by C/EBPα
Published in Leukemia (01-03-2016)“…B cells have been shown to be refractory to reprogramming and B-cell-derived induced pluripotent stem cells (iPSC) have only been generated from murine B cells…”
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Cisplatin-resistance and aggressiveness are enhanced by a highly stable endothelin-converting enzyme-1c in lung cancer cells
Published in Biological research (24-10-2024)“…Lung cancer constitutes the leading cause of cancer mortality. High levels of endothelin-1 (ET-1), its cognate receptor ET R and its activating enzyme, the…”
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Organs‐on‐Chips: Trends and Challenges in Advanced Systems Integration
Published in Advanced materials interfaces (01-11-2022)“…Organ‐on‐chip platforms combined with high‐throughput sensing technology allow bridging gaps in information presented by 2D cultures modeled on static…”
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Immunophenotypic analysis and quantification of B-1 and B-2 B cells during human fetal hematopoietic development
Published in Leukemia (01-07-2016)Get full text
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Inflammatory and Pro-resolving Lipids in Trypanosomatid Infections: A Key to Understanding Parasite Control
Published in Frontiers in microbiology (21-08-2018)“…Pathogenic trypanosomatids ( , and spp.) are protozoan parasites that cause neglected diseases affecting millions of people in Africa, Asia, and the Americas…”
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Gold/silver/gold trilayer films on nanostructured polycarbonate substrates for direct and label‐free nanoplasmonic biosensing
Published in Journal of biophotonics (01-08-2018)“…Ultrasmooth gold/silver/gold trilayer nanostructured plasmonic sensors were obtained using commercial Blu‐ray optical discs as nanoslits‐based flexible polymer…”
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Indomethacin Induces Spermidine/Spermine-N1-Acetyltransferase-1 via the Nucleolin-CDK1 Axis and Synergizes with the Polyamine Oxidase Inhibitor Methoctramine in Lung Cancer Cells
Published in Biomolecules (Basel, Switzerland) (12-09-2023)“…Indomethacin is a non-selective NSAID used against pain and inflammation. Although cyclooxygenase (COX) inhibition is considered indomethacin’s primary action…”
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Patient profiles as an aim to optimize selection in the second line setting: the role of aflibercept
Published in Clinical & translational oncology (01-08-2021)“…Colorectal cancer is the second leading cause of cancer-related death worldwide. For metastatic colorectal cancer (mCRC) patients, it is recommended, as…”
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Chitosan-G-Glycidyl Methacrylate/Au Nanocomposites Promote Accelerated Skin Wound Healing
Published in Pharmaceutics (01-09-2022)“…Herein, we report the synthesis of Au nanoparticles (AuNPs) in chitosan (CTS) solution by chemically reducing HAuCl4. CTS was further functionalized with…”
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In vitro and in vivo activity of voriconazole and benznidazole combination on trypanosoma cruzi infection models
Published in Acta tropica (01-11-2020)“…•In vitro and in vivo models of T. cruzi infection were developed for drug combination study, using voriconazole (VCZ) and benznidazole (BZ).•For both drugs,…”
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Protective role of acetylsalicylic acid in experimental Trypanosoma cruzi infection: evidence of a 15-epi-lipoxin A₄-mediated effect
Published in PLoS neglected tropical diseases (2013)“…Chagas' disease, produced by Trypanosoma cruzi, affects more than 8 million people, producing approximately 10,000 deaths each year in Latin America. Migration…”
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Brain areas interconnected to ventral pathway circuits are independently able to induce enhancement in object recognition memory and cause reversal in object recognition memory deficit
Published in CNS neuroscience & therapeutics (01-04-2024)“…Aims Ventral pathway circuits are constituted by the interconnected brain areas that are distributed throughout the brain. These brain circuits are primarily…”
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Thermal-Diffusivity Measurements of Mexican Citrus Essential Oils Using Photoacoustic Methodology in the Transmission Configuration
Published in International journal of thermophysics (01-05-2011)“…Photoacoustic methodology in the transmission configuration (PMTC) was used to study the thermophysical properties and their relation with the composition in…”
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Biogeography, cryptic diversity, and queen dimorphism evolution of the Neotropical ant genus Ectatomma Smith, 1958 (Formicidae, Ectatomminae)
Published in Organisms diversity & evolution (01-09-2015)“…Due to its high biodiversity and its complex climatic and geological history, the Neotropical region has caught the attention of evolutionary and conservation…”
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Kinetic analysis of a general model of activation of aspartic proteinase zymogens involving a reversible inhibitor. II. Contribution of the uni- and bimolecular activation routes
Published in Journal of enzyme inhibition and medicinal chemistry (01-04-2007)“…From the kinetic study carried out in part I of this series (preceding article) an analysis quantifying the relative contribution to the global process of the…”
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Direct and Label-Free Monitoring of Albumin in 2D Fatty Liver Disease Model Using Plasmonic Nanogratings
Published in Nanomaterials (Basel, Switzerland) (15-12-2020)“…Non-alcoholic fatty liver (NAFLD) is a metabolic disorder related to a chronic lipid accumulation within the hepatocytes. This disease is the most common liver…”
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EP-1673: Position accuracy of HexaPOD couch in combination with Elekta XVI-CBCT weekly test
Published in Radiotherapy and oncology (01-04-2015)Get full text
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Kinetic analysis of a general model of activation of aspartic proteinase zymogens involving a reversible inhibitor. I. Kinetic analysis
Published in Journal of enzyme inhibition and medicinal chemistry (01-01-2007)“…Starting from a simple general reaction mechanism of activation of aspartic proteinases zymogens involving a uni- and a bimolecular simultaneous activation…”
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Scalable, Lithography-Free Plasmonic Metasurfaces by Nano-Patterned/Sculpted Thin Films for Biosensing
Published in Frontiers in sensors (27-06-2022)“…Scientific research in plasmonic metasurfaces has been widely widespread in the last years, motivated by the recent advances in the nanofabrication field and…”
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