Search Results - "López Longo, Francisco J."
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Platelet soluble CD40L and matrix metalloproteinase 9 activity are proinflammatory mediators in Behçet disease patients
Published in Thrombosis and haemostasis (01-01-2012)“…Platelets are the major source of plasma-soluble CD40L (sCD40L), an important inflammatory mediator. This study explored the impact of platelet-derived sCD40L…”
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Classification of Systemic Lupus Erythematosus: Systemic Lupus International Collaborating Clinics Versus American College of Rheumatology Criteria. A Comparative Study of 2,055 Patients From a Real‐Life, International Systemic Lupus Erythematosus Cohort
Published in Arthritis care & research (2010) (01-08-2015)“…Objective The new Systemic Lupus International Collaborating Clinics (SLICC) 2012 classification criteria aimed to improve the performance of systemic lupus…”
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3
Lack of Association between JAK3 Gene Polymorphisms and Cardiovascular Disease in Spanish Patients with Rheumatoid Arthritis
Published in BioMed research international (01-01-2015)“…Rheumatoid arthritis (RA) is a polygenic disease associated with accelerated atherosclerosis and increased cardiovascular (CV) mortality. JAK/STAT signalling…”
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Bacteremia in Systemic Lupus Erythematosus in Patients from a Spanish Registry: Risk Factors, Clinical and Microbiological Characteristics, and Outcomes
Published in Journal of rheumatology (01-02-2020)“…To describe the incidence of bacteremia in a large multicentric cohort of patients with systemic lupus erythematosus (SLE) and their clinical characteristics…”
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Identification of a 3′‐Untranslated Genetic Variant of RARB Associated With Carotid Intima‐Media Thickness in Rheumatoid Arthritis: A Genome‐Wide Association Study
Published in Arthritis & rheumatology (Hoboken, N.J.) (01-03-2019)“…Objective To investigate the genetic background influencing the development of cardiovascular (CV) disease in patients with rheumatoid arthritis (RA). Methods…”
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Interferon regulatory factor 5 genetic variants are associated with cardiovascular disease in patients with rheumatoid arthritis
Published in Arthritis research & therapy (10-07-2014)“…Rheumatoid arthritis (RA) is a complex polygenic inflammatory disease associated with accelerated atherosclerosis and increased cardiovascular (CV) disease…”
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Lack of Association between ABO, PPAP2B, ADAMST7, PIK3CG, and EDNRA and Carotid Intima-Media Thickness, Carotid Plaques, and Cardiovascular Disease in Patients with Rheumatoid Arthritis
Published in Mediators of Inflammation (01-01-2014)“…Introduction. Rheumatoid arthritis (RA) is a polygenic disease associated with accelerated atherosclerosis and increased cardiovascular (CV) mortality. Recent…”
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Osteoprotegerin CGA haplotype protection against cerebrovascular complications in anti-CCP negative patients with rheumatoid arthritis
Published in PloS one (03-09-2014)“…Rheumatoid arthritis is an inflammatory disease with high incidence of cardiovascular disease due to accelerated atherosclerosis. Osteoprotegerin (OPG) has…”
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SMAD3 rs17228212 gene polymorphism is associated with reduced risk to cerebrovascular accidents and subclinical atherosclerosis in anti-CCP negative Spanish rheumatoid arthritis patients
Published in PloS one (21-10-2013)“…Rheumatoid arthritis (RA) is a complex polygenic inflammatory disease associated with accelerated atherosclerosis and increased risk of cardiovascular (CV)…”
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Cardiovascular Events in Systemic Lupus Erythematosus: A Nationwide Study in Spain From the RELESSER Registry
Published in Medicine (Baltimore) (01-07-2015)“…This article estimates the frequency of cardiovascular (CV) events that occurred after diagnosis in a large Spanish cohort of patients with systemic lupus…”
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Late-onset versus early-onset systemic lupus: characteristics and outcome in a national multicentre register (RELESSER)
Published in Rheumatology (Oxford, England) (06-04-2021)“…Abstract Objective The aim of the present study was to describe the demographic, clinical and immunological characteristics of patients with late-onset (≥50…”
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12
Fibromyalgia prevalence and related factors in a large registry of patients with systemic lupus erythematosus
Published in Clinical and experimental rheumatology (01-03-2016)“…The objective of this study is to determine the prevalence of fibromyalgia (FM) in systemic lupus erythematosus (SLE) patients and to study its relationship to…”
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Endothelial Dysfunction and Altered Coagulation As Mediators of Thromboembolism in Behçet Disease
Published in Seminars in thrombosis and hemostasis (01-09-2015)“…Behçet disease (BD) is a rare multisystem, inflammatory disease of unknown etiology with vascular involvement and associated thrombogenicity. This review aims…”
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New insight on the Xq28 association with systemic sclerosis
Published in Annals of the rheumatic diseases (01-12-2013)“…To evaluate whether the systemic sclerosis (SSc)-associated IRAK1 non-synonymous single-nucleotide polymorphism rs1059702 is responsible for the Xq28…”
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Influence of elevated-CRP level-related polymorphisms in non-rheumatic Caucasians on the risk of subclinical atherosclerosis and cardiovascular disease in rheumatoid arthritis
Published in Scientific reports (18-08-2016)“…Association between elevated C-reactive protein (CRP) serum levels and subclinical atherosclerosis and cardiovascular (CV) events was described in rheumatoid…”
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Influence of coronary artery disease and subclinical atherosclerosis related polymorphisms on the risk of atherosclerosis in rheumatoid arthritis
Published in Scientific reports (06-01-2017)“…A genetic component influences the development of atherosclerosis in the general population and also in rheumatoid arthritis (RA). However, genetic…”
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Influence of the IL6 Gene in Susceptibility to Systemic Sclerosis
Published in Journal of rheumatology (01-12-2012)“…Systemic sclerosis (SSc) is a genetically complex autoimmune disease; the genetic component has not been fully defined. Interleukin 6 (IL-6) plays a crucial…”
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Behçet's disease: new insight into the relationship between procoagulant state, endothelial activation/damage and disease activity
Published in Orphanet journal of rare diseases (27-05-2013)“…Behçet disease (BD) is associated with a prothrombotic state of unknown origin that may lead to life-threatening events. Calibrated Automated Thrombogram (CAT)…”
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Confirmation of association of the macrophage migration inhibitory factor gene with systemic sclerosis in a large European population
Published in Rheumatology (Oxford, England) (01-11-2011)“…Objectives. The aim of this study was to confirm the implication of macrophage migration inhibitory factor (MIF) gene in SSc susceptibility or clinical…”
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Lack of replication of interactions between polymorphisms in rheumatoid arthritis susceptibility: case-control study
Published in Arthritis research & therapy (27-09-2014)“…Approximately 100 loci have been definitively associated with rheumatoid arthritis (RA) susceptibility. However, they explain only a fraction of RA…”
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