Search Results - "López‐Ruiz, Elena"

Cancer: a mirrored room between tumor bulk and tumor microenvironment by Hernández-Camarero, Pablo, López-Ruiz, Elena, Marchal, Juan Antonio, Perán, Macarena

“…It has been well documented that the tumor microenvironment (TME) plays a key role in the promotion of drug resistance, the support of tumor progression,…”
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DNA specificities modulate the binding of human transcription factor A to mitochondrial DNA control region by Cuppari, Anna, Fernández-Millán, Pablo, Battistini, Federica, Tarrés-Solé, Aleix, Lyonnais, Sébastien, Iruela, Guillermo, Ruiz-López, Elena, Enciso, Yuliana, Rubio-Cosials, Anna, Prohens, Rafel, Pons, Miquel, Alfonso, Carlos, Tóth, Katalin, Rivas, Germán, Orozco, Modesto, Solà, Maria

“…Abstract Human mitochondrial DNA (h-mtDNA) codes for 13 subunits of the oxidative phosphorylation pathway, the essential route that produces ATP. H-mtDNA…”
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Unifying Different Cancer Theories in a Unique Tumour Model: Chronic Inflammation and Deaminases as Meeting Points by Hernández-Camarero, Pablo, López-Ruiz, Elena, Marchal, Juan Antonio, Perán, Macarena

“…The increase in cancer incidences shows that there is a need to better understand tumour heterogeneity to achieve efficient treatments. Interestingly, there…”
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Melanoma cancer stem-like cells: Optimization method for culture, enrichment and maintenance by Yaiza, Jiménez Martínez, Gloria, Ruiz Alcalá, María Belén, García Ortega, Elena, López-Ruiz, Gema, Jiménez, Juan Antonio, Marchal, María Ángel, García Chaves, Houria, Boulaiz

“…•Human mesenchymal stem cells (MSCs) isolation methods affect the quality of their secretome.•MSCs isolated by the non-enzymatic methodology displayed higher…”
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Primary Leiomyosarcoma of the Ovarian Vein: Case Report and Literature Review by López-Ruiz, María Elena, Yébenes, Laura, Berjón, Alberto, Hardisson, David

“…Primary leiomyosarcoma arising from the ovarian vein is extremely rare, with only 10 cases reported in the literature. We report on a case of leiomyosarcoma of…”
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Current Status of the Diagnosis and Management of Osteoporosis by Aibar-Almazán, Agustín, Voltes-Martínez, Ana, Castellote-Caballero, Yolanda, Afanador-Restrepo, Diego Fernando, Carcelén-Fraile, María del Carmen, López-Ruiz, Elena

“…Osteoporosis has been defined as the silent disease of the 21st century, becoming a public health risk due to its severity, chronicity and progression and…”
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A hyaluronic acid-based hydrogel enabling CD44-mediated chondrocyte binding and gapmer oligonucleotide release for modulation of gene expression in osteoarthritis by Cai, Yunpeng, López-Ruiz, Elena, Wengel, Jesper, Creemers, Laura B., Howard, Kenneth A.

“…Hyaluronic acid (HA) is an attractive biomaterial for osteoarthritis (OA) treatment due to inherent functional and compatibility properties as an endogenous…”
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Revisiting the dynamic cancer stem cell model: Importance of tumour edges by Hernández-Camarero, Pablo, Jiménez, Gema, López-Ruiz, Elena, Barungi, Shivan, Marchal, Juan Antonio, Perán, Macarena

“…The lack of an effective treatment against cancer is not only due to its huge heterogeneity, but also to the fact that we don’t have an answer to the question…”
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Gastric necrosis: A late complication of nissen fundoplication by Salinas, Javier

“…Gastric necrosis is a rare condition because of the rich blood supply and the extensive submucosal vascular network of the stomach. “Gas-bloat” syndrome is a…”
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Biofabrication approaches and regulatory framework of metastatic tumor‐on‐a‐chip models for precision oncology by Nieto, Daniel, Jiménez, Gema, Moroni, Lorenzo, López‐Ruiz, Elena, Gálvez‐Martín, Patricia, Marchal, Juan Antonio

“…The complexity of the tumor microenvironment (TME) together with the development of the metastatic process are the main reasons for the failure of conventional…”
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Role of Mesenchymal Stromal Cells as Therapeutic Agents: Potential Mechanisms of Action and Implications in Their Clinical Use by Jimenez-Puerta, Gonzalo José, Marchal, Juan Antonio, López-Ruiz, Elena, Gálvez-Martín, Patricia

“…Due to the great therapeutic interest that involves the translation of mesenchymal stromal cells (MSCs) into clinical practice, they have been widely studied…”
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Structural analysis of the Candida albicans mitochondrial DNA maintenance factor Gcf1p reveals a dynamic DNA-bridging mechanism by Tarrés-Solé, Aleix, Battistini, Federica, Gerhold, Joachim M, Piétrement, Olivier, Martínez-García, Belén, Ruiz-López, Elena, Lyonnais, Sébastien, Bernadó, Pau, Roca, Joaquim, Orozco, Modesto, Le Cam, Eric, Sedman, Juhan, Solà, Maria

“…Abstract The compaction of mitochondrial DNA (mtDNA) is regulated by architectural HMG-box proteins whose limited cross-species similarity suggests diverse…”
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Development of a Biomimetic Hydrogel Based on Predifferentiated Mesenchymal Stem‐Cell‐Derived ECM for Cartilage Tissue Engineering by Antich, Cristina, Jiménez, Gema, Vicente, Juan, López‐Ruiz, Elena, Chocarro‐Wrona, Carlos, Griñán‐Lisón, Carmen, Carrillo, Esmeralda, Montañez, Elvira, Marchal, Juan A.

“…The use of decellularized extracellular matrix (dECM) as a biomaterial has been an important step forward for the development of functional tissue constructs…”
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Self‐Assembled Type I Collagen‐Apatite Fibers with Varying Mineralization Extent and Luminescent Terbium Promote Osteogenic Differentiation of Mesenchymal Stem Cells by Romero‐Castillo, Ismael, López‐Ruiz, Elena, Fernández‐Sánchez, Jorge Fernando, Marchal, Juan Antonio, Gómez‐Morales, Jaime

“…This work explores in depth the simultaneous self‐assembly and mineralization of type I collagen by a base‐acid neutralization technique to prepare biomimetic…”
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miRNAs as radio‐response biomarkers for breast cancer stem cells by Griñán‐Lisón, Carmen, Olivares‐Urbano, María Auxiliadora, Jiménez, Gema, López‐Ruiz, Elena, Val, Coral, Morata‐Tarifa, Cynthia, Entrena, José Manuel, González‐Ramírez, Amanda Rocío, Boulaiz, Houria, Zurita Herrera, Mercedes, Núñez, María Isabel, Marchal, Juan Antonio

“…In breast cancer (BC), the presence of cancer stem cells (CSCs) has been related to relapse, metastasis, and radioresistance. Radiotherapy (RT) is an extended…”
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Advances in spray products for skin regeneration by Pleguezuelos-Beltrán, Paula, Gálvez-Martín, Patricia, Nieto-García, Daniel, Marchal, Juan Antonio, López-Ruiz, Elena

“…To date, skin wounds are still an issue for healthcare professionals. Although numerous approaches have been developed over the years for skin regeneration,…”
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Eggshell Membrane as a Biomaterial for Bone Regeneration by Torres-Mansilla, Adriana, Hincke, Maxwell, Voltes, Ana, López-Ruiz, Elena, Baldión, Paula Alejandra, Marchal, Juan Antonio, Álvarez-Lloret, Pedro, Gómez-Morales, Jaime

“…The physicochemical features of the avian eggshell membrane play an essential role in the process of calcium carbonate deposition during shell mineralization,…”
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Design and evaluation of a bilayered dermal/hypodermal 3D model using a biomimetic hydrogel formulation by Chocarro-Wrona, Carlos, López de Andrés, Julia, Rioboó-Legaspi, Pablo, Pleguezuelos-Beltrán, Paula, Antich, Cristina, De Vicente, Juan, Gálvez-Martín, Patricia, López-Ruiz, Elena, Marchal, Juan Antonio

“…Due to the limitations of the current skin wound treatments, it is highly valuable to have a wound healing formulation that mimics the extracellular matrix…”
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Plastic degradation by insect hexamerins: Near-atomic resolution structures of the polyethylene-degrading proteins from the wax worm saliva by Spínola-Amilibia, Mercedes, Illanes-Vicioso, Ramiro, Ruiz-López, Elena, Colomer-Vidal, Pere, Rodriguez-Ventura, Francisco, Peces Pérez, Rosa, Arias, Clemente F., Torroba, Tomas, Solà, Maria, Arias-Palomo, Ernesto, Bertocchini, Federica

“…Plastic waste management is a pressing ecological, social, and economic challenge. The saliva of the lepidopteran Galleria mellonella larvae is capable of…”
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Pancreatic (pro)enzymes treatment suppresses BXPC-3 pancreatic Cancer Stem Cell subpopulation and impairs tumour engrafting by Hernández-Camarero, Pablo, López-Ruiz, Elena, Griñán-Lisón, Carmen, García, María Ángel, Chocarro-Wrona, Carlos, Marchal, Juan Antonio, Kenyon, Julian, Perán, Macarena

“…Cancer stem cells (CSCs) subpopulation within the tumour is responsible for metastasis and cancer relapse. Here we investigate in vitro and in vivo the effects…”
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