Search Results - "López‐Méndez, Luis José"
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Mono-Dendronized β‑Cyclodextrin Derivatives as Multitasking Containers for Curcumin. Impacting Its Solubility, Loading, and Tautomeric Form
Published in The journal of physical chemistry. B (24-02-2022)“…In this study, three mono-dendronized β-cyclodextrin (βCD) derivatives (βCD-1G, βCD-2G, and βCD-3G) were used as multitasking containers of curcumin (CUR) to…”
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Antidepressant-like and Beneficial Effects of a Neoponcirin-Beta-Cyclodextrin Inclusion Complex in Mice Exposed to Prolonged Stress
Published in International journal of molecular sciences (01-08-2024)“…Neoponcirin causes anxiolytic-like effects in mice when administered intraperitoneally but not orally. Neoponcirin is non-water-soluble and insoluble in…”
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Inclusion and Non‐Inclusion Complexes between Curcumin and β‐Cyclodextrin with High‐Curcumin Loading and Enhanced Aqueous Solubility Obtained by Mechanochemistry
Published in ChemistrySelect (Weinheim) (05-12-2023)“…In this study, we employ mechanochemistry as an innovative strategy, using a Planetary Mill, to obtain supramolecular structures in the solid state between…”
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Dendronization: A practical strategy to improve the performance of molecular systems used in biomedical applications
Published in European journal of medicinal chemistry (05-02-2022)“…Nanomedicine is an emerging area that largely influences the efficacy of various therapies through the rational design of new materials exhibiting more…”
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PEGylated β-cyclodextrins: Click synthesis and in vitro biological insights
Published in Carbohydrate polymers (01-11-2019)“…[Display omitted] •Three PEGylated star-shaped βcyclodextrins were synthesized.•β-Cyclodextrin PEGylation was efficiently addressed by click chemistry.•Effect…”
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Convergent click synthesis of macromolecular dendritic β-cyclodextrin derivatives as non-conventional drug carriers: Albendazole as guest model
Published in International journal of biological macromolecules (01-12-2020)“…From a materials science perspective, herein we present the design and synthesis of six macromolecular carbohydrate derivatives, obtained by combining the…”
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β-cyclodextrin dendritic derivatives as permeation mediators to enhance the in vitro albendazole cysticidal activity by the improvement of the diffusion component
Published in RSC advances (16-08-2022)“…The improvement of permeation of drugs across parasites' membranes to promote their diffusion component represents a challenge to achieve better therapeutic…”
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Synthesis of a poly(ester) dendritic β-cyclodextrin derivative by “click” chemistry: Combining the best of two worlds for complexation enhancement
Published in Carbohydrate polymers (15-03-2018)“…[Display omitted] •A βcyclodextrin-poly(ester) dendritic structure was synthesized.•Click chemistry is an efficient approach to “dendronize” βcyclodextrin…”
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On the conformational search of a βCD dendritic derivative: NMR and theoretical calculations working together reveal a donut-like amphiphilic structure
Published in Journal of molecular structure (15-03-2020)“…The conformational behavior of host molecular systems is intimately related to their performance, both as molecular containers and as interfaces in biological…”
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The mechanochemical and supercritical fluid synthesis of β-cyclodextrin-hesperidin inclusion complex: A comparison green chemistry versus lyophilization
Published in The Journal of supercritical fluids (01-01-2025)“…Hesperidin is a rutinoside of flavanone type with relevant therapeutic properties but poor water solubility which limits its therapeutic applicability…”
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β-cyclodextrin dendritic derivatives as permeation mediators to enhance the albendazole cysticidal activity by the improvement of the diffusion component
Published in RSC advances (17-08-2022)“…The improvement of permeation of drugs across parasites' membranes to promote their diffusion component represents a challenge to achieve better therapeutic…”
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La economía gallega ante los retos del siglo XXI
Published in Revista galega de economía (01-01-2000)Get full text
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