Electrochemical Immunosensors: The Evolution from Elisa to EμPADs

Electrochemical immunosensors comprise the merging of two different disciplines: molecular biology and electrochemistry. This review explains in depth the main parts of electrochemical immunosensors and how the enzyme‐linked immunosorbent assay (ELISA) has been integrated into sophisticated “lab‐on‐...

Full description

Saved in:

Bibliographic Details
Published in:	Electroanalysis (New York, N.Y.) Vol. 35; no. 4
Main Authors:	Ochoa‐Ruiz, Andrea Gabriela, Parra, Guillermo, López‐Espinoza, Diego, Astudillo, Pablo, Galyamin, Dmitry, Sabaté, Neus, Esquivel, Juan Pablo, Vallejo‐Cardona, Alba Adriana
Format:	Journal Article
Language:	English
Published:	01-04-2023
Subjects:	biosensors electrochemistry ELISA immunosensors paper-based point of care
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Description
Summary:	Electrochemical immunosensors comprise the merging of two different disciplines: molecular biology and electrochemistry. This review explains in depth the main parts of electrochemical immunosensors and how the enzyme‐linked immunosorbent assay (ELISA) has been integrated into sophisticated “lab‐on‐a‐chip” and “point‐of‐care” devices. It also reviews how nanotechnology has been a powerful tool for achieving lower detection limits, more signal amplification, and constructing label‐free devices. It finally explores the new perspectives on electrochemical immunosensors to integrate them in novel paper microfluidic devices called EμPADs. Colleagues introducing themselves to the topic for the first time will find in this review a comprehensive revision of how the basics of the technology have given rise to the emerging topic of EμPADs.
ISSN:	1040-0397 1521-4109
DOI:	10.1002/elan.202200053