Search Results - "López‐Díaz de Cerio, Ascensión"
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MRP1-CD28 bi-specific oligonucleotide aptamers: target costimulation to drug-resistant melanoma cancer stem cells
Published in Oncotarget (26-04-2016)“…In this work we show a clinically feasible strategy to convert in situ the own tumor into an endogenous vaccine by coating the melanoma cancerous cells with…”
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Idiotype vaccines produced with a non-cytopathic alphavirus self-amplifying RNA vector induce antitumor responses in a murine model of B-cell lymphoma
Published in Scientific reports (02-11-2021)“…A promising therapy for patients with B-cell lymphoma is based on vaccination with idiotype monoclonal antibodies (mAbs). Since idiotypes are different in each…”
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Assessing the impact of the addition of dendritic cell vaccination to neoadjuvant chemotherapy in breast cancer patients: A model‐based characterization approach
Published in British journal of clinical pharmacology (01-08-2019)“…Aims Immunotherapy is a rising alternative to traditional treatment in breast cancer (BC) patients in order to transform cold into hot immune enriched tumours…”
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C5a elevation in convalescents from severe COVID-19 is not associated with early complement activation markers C3bBbP or C4d
Published in Frontiers in immunology (24-08-2022)“…Numerous publications have underlined the link between complement C5a and the clinical course of COVID-19. We previously reported that levels of C5a remain…”
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Immunologic characterization of COVID-19 patients with hematological cancer
Published in Haematologica (Roma) (17-12-2020)Get full text
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Maintenance therapy with ex vivo expanded lymphokine‐activated killer cells and rituximab in patients with follicular lymphoma is safe and may delay disease progression
Published in British journal of haematology (01-06-2020)“…Summary Anti‐cluster of differentiation 20 (CD20) monoclonal antibodies (mAbs) have shown promise in follicular lymphoma (FL) as post‐induction therapy, by…”
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Immunological Biomarkers of Fatal COVID-19: A Study of 868 Patients
Published in Frontiers in immunology (03-05-2021)“…Information on the immunopathobiology of coronavirus disease 2019 (COVID-19) is rapidly increasing; however, there remains a need to identify immune features…”
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Idiotype vaccine production using hybridoma technology
Published in Methods in molecular biology (Clifton, N.J.) (2014)“…Non-Hodgkin's lymphoma (NHL) is the most common hematological malignancy both in Europe and in the United States. Follicular lymphoma (FL), a tumor comprised…”
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Abnormal Priming of CD4+ T Cells by Dendritic Cells Expressing Hepatitis C Virus Core and E1 Proteins
Published in Journal of Virology (01-05-2002)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Neoadjuvant nivolumab modifies the tumor immune microenvironment in resectable glioblastoma
Published in Nature medicine (01-03-2019)“…Glioblastoma is the most common primary central nervous system malignancy and has a poor prognosis. Standard first-line treatment, which includes surgery…”
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2-fluoro-RNA oligonucleotide CD40 targeted aptamers for the control of B lymphoma and bone-marrow aplasia
Published in Biomaterials (01-10-2015)“…Abstract Recent studies have underscored the importance of immunomodulatory antibodies in the treatment of solid and hematological tumors. ODN-Aptamers are…”
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Targeting NK-cell checkpoints for cancer immunotherapy
Published in Current opinion in immunology (01-04-2017)“…Highlights • NK cells are cytotoxic lymphocytes with potential for cancer immunotherapy. • NK-cell numbers and function are regulated by surface receptors and…”
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Fractionated initial infusion and booster dose of ARI0002h, a humanised, BCMA-directed CAR T-cell therapy, for patients with relapsed or refractory multiple myeloma (CARTBCMA-HCB-01): a single-arm, multicentre, academic pilot study
Published in The lancet oncology (01-08-2023)“…Chimeric antigen receptor (CAR) T-cell therapy is a promising option for patients with heavily treated multiple myeloma. Point-of-care manufacturing can…”
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Imiquimod Enhances the Systemic Immunity Attained by Local Cryosurgery Destruction of Melanoma Lesions
Published in Journal of investigative dermatology (01-07-2007)“…Melanoma lesions can be frozen in vivo, resulting in necrotic death of malignant cells and in tumor antigen release suitable for cross-presentation by…”
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Combined vaccination with idiotype-pulsed allogeneic dendritic cells and soluble protein idiotype for multiple myeloma patients relapsing after reduced-intensity conditioning allogeneic stem cell transplantation
Published in Leukemia & lymphoma (2006)“…Background and objective: To combine the use of idiotype-pulsed allogeneic dendritic cells (alloDC) and soluble protein Id conjugated with KLH (Id-KLH) in a…”
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Immunization with a tumor‐associated CTL epitope plus a tumor‐related or unrelated Th1 helper peptide elicits protective CTL immunity
Published in European journal of immunology (01-06-2001)“…Immunization with cytotoxic T cell epitope SPSYVYHQF (AH1), derived from MuLV gp70 envelope protein expressed by CT26 tumor cells, does not protect BALB/c mice…”
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Serum mass spectrometry for treatment monitoring in patients with multiple myeloma receiving ARI0002h CAR T-cells
Published in British journal of haematology (01-10-2024)“…Chimeric antigen receptor (CAR) T-cell therapies have increased the patients with relapsed/refractory multiple myeloma (RRMM) in whom standard electrophoretic…”
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Follicular lymphoma: in vitro effects of combining lymphokine-activated killer (LAK) cell-induced cytotoxicity and rituximab- and obinutuzumab-dependent cellular cytotoxicity (ADCC) activity
Published in Immunologic research (01-04-2016)“…Follicular lymphoma (FL) is a disease of paradoxes—incurable but with a long natural history. We hypothesized that a combination of lymphokine-activated killer…”
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A randomized phase II clinical trial of dendritic cell vaccination following complete resection of colon cancer liver metastasis
Published in Journal for immunotherapy of cancer (29-09-2018)“…Surgically resectable synchronic and metachronic liver metastases of colon cancer have high risk of relapse in spite of standard-of-care neoadjuvant and…”
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Variations in “rescuability” of immunoglobulin molecules from different forms of human lymphoma: implications for anti-idiotype vaccine development
Published in Critical reviews in oncology/hematology (01-10-2004)“…Idiotypic (Id) vaccination has shown promising results in patients with follicular lymphoma (FL). However, it still remains unclear whether the same approach…”
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