Search Results - "López‐Arrieta, Jesús"

Masitinib for mild-to-moderate Alzheimer's disease: results from a randomized, placebo-controlled, phase 3, clinical trial by Dubois, Bruno, López-Arrieta, Jesús, Lipschitz, Stanley, Doskas, Triantafyllos, Spiru, Luiza, Moroz, Svitlana, Venger, Olena, Vermersch, Patrick, Moussy, Alain, Mansfield, Colin D, Hermine, Olivier, Tsolaki, Magda

“…Masitinib is an orally administered tyrosine kinase inhibitor that targets activated cells of the neuroimmune system (mast cells and microglia). Study AB09004…”
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Correction: Masitinib for mild-to-moderate Alzheimer's disease: results from a randomized, placebo-controlled, phase 3, clinical trial by Dubois, Bruno, López-Arrieta, Jesús, Lipschitz, Stanley, Doskas, Triantafyllos, Spiru, Luiza, Moroz, Svitlana, Venger, Olena, Vermersch, Patrick, Moussy, Alain, Mansfield, Colin D, Hermine, Olivier, Tsolaki, Magda

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Prospective one-year cost-of-illness study in a cohort of patients with dementia of Alzheimer's disease type in Spain: the ECO study by Coduras, Alicia, Rabasa, Isabel, Frank, Ana, Bermejo-Pareja, Felix, López-Pousa, Secundino, López-Arrieta, Jesús-María, Del Llano, Juan, León, Teresa, Rejas, Javier

“…In this study, we analyzed the economic impact of one-year healthcare and non-healthcare resources utilization by patients with dementia of Alzheimer's disease…”
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Instrumental activities of daily living in the screening of dementia in population studies: a systematic review and meta-analysis by Castilla-Rilo, Juan, López-Arrieta, Jesús, Bermejo-Pareja, Felix, Ruiz, Miguel, Sánchez-Sánchez, Fernando, Trincado, Rocío

“…Background Despite the fact that the current definitions of dementia in the DSM‐IV and ICD‐10 require functional deterioration for the diagnosis of dementia,…”
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Genetic association of complement receptor 1 polymorphism rs3818361 in Alzheimer’s disease by Antúnez, Carmen, Boada, Mercè, López-Arrieta, Jesús, Moreno-Rey, Concha, Hernández, Isabel, Marín, Juan, Gayán, Javier, González-Pérez, Antonio, Real, Luis M, Alegret, Montserrat, Tárraga, Lluis, Ramírez-Lorca, Reposo, Ruiz, Agustín

“…Abstract Complement receptor 1 gene polymorphism rs3818361 was recently shown to increase the risk of Alzheimer’s disease (AD). We performed an independent…”
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Effectiveness of acute geriatric units on functional decline, living at home, and case fatality among older patients admitted to hospital for acute medical disorders: meta-analysis by BAZTAN, Juan J, SUAREZ-GARCIA, Francisco M, LOPEZ-ARRIETA, Jesus, RODRIGUEZ-MANAS, Leocadio, RODRIGUEZ-ARTALEJO, Fernando

“…Objective To assess the effectiveness of acute geriatric units compared with conventional care units in adults aged 65 or more admitted to hospital for acute…”
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Is milk and dairy intake a preventive factor for elderly cognition (dementia and Alzheimer’s)? A quality review of cohort surveys by Bermejo-Pareja, Félix, Ciudad-Cabañas, María José, Llamas-Velasco, Sara, Tapias-Merino, Ester, Hernández Gallego, Jesús, Hernández-Cabria, Marta, Collado-Yurrita, Luis, López-Arrieta, Jesús María

“…Abstract Milk and dairy (M&D) is a longstanding human food with widespread use. Many studies showed the preventive capacity of M&D in several human health…”
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Estrogen receptor alpha gene variants are associated with Alzheimer's disease by Boada, Mercé, Antunez, Carmen, López-Arrieta, Jesús, Caruz, Antonio, Moreno-Rey, Concha, Ramírez-Lorca, Reposo, Morón, Francisco Jesús, Hernández, Isabel, Mauleón, Ana, Rosende-Roca, Maiteé, Martínez-Lage, Pablo, Marín, Juan, Tárraga, Lluis, Alegret, Montserrat, Pedrajas, José Rafael, Urda, Nuria, Royo, José Luis, Saez, María Eugenia, Gayán, Javier, González-Pérez, Antonio, Real, Luis Miguel, Ruiz, Agustín, Galán, José Jorge

“…Abstract The present research is aimed at assessing the role of 3 estrogen receptor alpha (ESR1) gene variants in late onset Alzheimer's disease (AD)…”
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Evaluation of Candidate Genes Related to Neuronal Apoptosis in Late-Onset Alzheimer’s Disease by Moreno-Grau, Sonia, Barneda, Bruna, Carriba, Paulina, Marín, Juan, Sotolongo-Grau, Oscar, Hernández, Isabel, Rosende-Roca, Maitée, Mauleón, Ana, Vargas, Liliana, Espinosa, Ana, Alegret, Montserrat, Rodriguez, Octavio, Ortega, Gemma, Fernández, Maria Victoria, López-Arrieta, Jesús, Tárraga, Lluís, Boada, Mercè, Antúnez, Carmen, López, Joaquin, Ruiz, Agustín, Comella, Joan Xavier

“…The objective of this study was to identify genetic variation in genes encoding death receptors and signals that modulate their activity. After conducting a…”
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Methodology, results and quality of clinical trials of tacrine in the treatment of Alzheimer's disease: a systematic review of the literature by ARRIETA, JESÚS LÓPEZ, ARTALEJO, FERNANDO RODRÍGUEZ

“…Objective: to review systematically the methodology, results and quality of clinical trials of tacrine in the treatment of Alzheimer's disease (AD). Methods:…”
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The MTHFD1L gene rs11754661 marker is not associated with Alzheimer's disease in a sample of the Spanish population by Ramírez-Lorca, Reposo, Boada, Mercé, Antúnez, Carmen, López-Arrieta, Jesús, Moreno-Rey, Concha, Hernández, Isabel, Marín, Juan, Gayán, Javier, González-Pérez, Antonio, Alegret, Montserrat, Tárraga, Lluis, Real, Luis M, Ruiz, Agustín

“…The MTHFD1L gene SNP variant rs11754661 was found to increase the risk of Alzheimer's disease in a recent Whole Genome Association Study. We have carried out…”
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GOLPH2 gene markers are not associated with Alzheimer's disease in a sample of the Spanish population by Antúnez, Carmen, Boada, Mercé, López-Arrieta, Jesús, Ramirez-Lorca, Reposo, Hernández, Isabel, Marín, Juan, Martínez-Lage, Pablo, González-Pérez, Antonio, Jorge Galan, José, Gayán, Javier, Real, Luis M, Ruiz, Agustín

“…GOLPH2 gene SNP variants Rs10868366 and Rs7019241 were reported to decrease the risk of Alzheimer's disease in a recent Whole Genome Association Study. We have…”
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Impact of hospital admission on centenarians admitted due to an acute illness. A description of a series of 165 cases and comparison with the literature by Sáez-Nieto, Carmen, Ly-Yang, Fernando, Pérez-Rodríguez, Patricia, Alarcón, Teresa, López-Arrieta, Jesús, González-Montalvo, Juan Ignacio

“…The number of centenarians is increasing with the aging of the Spanish population. This age group might present different clinical features from younger…”
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Factors associated with the positive impact of caring for elderly and dependent relatives by López, Javier, López-Arrieta, Jesús, Crespo, María

“…Until recent years, the research on caregivers of dependent dwelling elder subjects has dealt with the negative aspects of caregiving (e.g. depression,…”
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Are the effects of age and education on neuropsychological performance the same in healthy individuals, individuals with mild cognitive impairment and those with Alzheimer's disease? by Lubrini, Genny, Gozalbo, Ana Simón, Vincent, Clarissa, Acedo, Carmen, López-Arrieta, Jesús, Garcia, Ana Frank

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P2–285: Are the effects of age and education on neuropsychological performance the same in healthy individuals, individuals with mild cognitive impairment and those with Alzheimer's disease? by Lubrini, Genny, Gozalbo, Ana Simón, Vincent, Clarissa, Acedo, Carmen, López‐Arrieta, Jesús, Garcia, Ana Frank

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Assessing the role of the TREM2 p.R47H variant as a risk factor for Alzheimer's disease and frontotemporal dementia by Ruiz, Agustín, Dols-Icardo, Oriol, Bullido, María J, Pastor, Pau, Rodríguez-Rodríguez, Eloy, López de Munain, Adolfo, de Pancorbo, Marian M, Pérez-Tur, Jordi, Álvarez, Victoria, Antonell, Anna, López-Arrieta, Jesús, Hernández, Isabel, Tárraga, Lluís, Boada, Mercè, Lleó, Alberto, Blesa, Rafael, Frank-García, Ana, Sastre, Isabel, Razquin, Cristina, Ortega-Cubero, Sara, Lorenzo, Elena, Sánchez-Juan, Pascual, Combarros, Onofre, Moreno, Fermín, Gorostidi, Ana, Elcoroaristizabal, Xabier, Baquero, Miquel, Coto, Eliecer, Sánchez-Valle, Raquel, Clarimón, Jordi

“…Abstract A non-synonymous genetic rare variant, rs75932628-T (p.R47H), in the TREM2 gene has recently been reported to be a strong genetic risk factor for…”
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The health status: the ignored risk factor in dementia incidence. NEDICES cohort by Bermejo-Pareja, Félix, Gómez de la Cámara, Agustín, del Ser, Teodoro, Contador, Israel, Llamas-Velasco, Sara, López-Arrieta, Jesús María, Martín-Arriscado, Cristina, Hernández-Gallego, Jesús, Vega, Saturio, Benito-León, Julián

“…Background The causes of the dementia decrease in affluent countries are not well known but health amelioration could probably play a major role. Nevertheless,…”
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CALHM1 P86L polymorphism is associated with late-onset Alzheimer's disease in a recessive model by Boada, Mercè, Antúnez, Carmen, López-Arrieta, Jesús, Galán, José Jorge, Morón, Francisco J, Hernández, Isabel, Marín, Juan, Martínez-Lage, Pablo, Alegret, Montserrat, Carrasco, Jose M, Moreno, Concha, Real, Luis M, González-Pérez, Antonio, Tárraga, Lluís, Ruiz, Agustín

“…CALHM1 gene coding non-synonymous SNP P86L (rs2986017) was reported to increase the risk of Alzheimer's disease (AD) in a recent study. We have investigated…”
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Impacto de la hospitalización en pacientes centenarios ingresados por enfermedad aguda. Descripción de una serie de 165 casos y comparación con la literatura by Sáez-Nieto, Carmen, Ly-Yang, Fernando, Pérez-Rodríguez, Patricia, Alarcón, Teresa, López-Arrieta, Jesús, González-Montalvo, Juan Ignacio

“…ResumenIntroducciónEl envejecimiento de la población está suponiendo un aumento de pacientes centenarios, cuyas características podrían diferenciarse de las de…”
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