Search Results - "López, J. Alejandro"

Targeted Therapies for Triple-Negative Breast Cancer: Combating a Stubborn Disease by Kalimutho, Murugan, Parsons, Kate, Mittal, Deepak, López, J. Alejandro, Srihari, Sriganesh, Khanna, Kum Kum

“…Triple-negative breast cancers (TNBCs) constitute a heterogeneous subtype of breast cancers that have a poor clinical outcome. Although no approved targeted…”
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Efficient carbon nanotube sponges production boosted by acetone in CVD-Synthesis by Cortés-López, Alejandro J., Muñoz-Sandoval, Emilio, López-Urías, Florentino

“…A high production of nitrogen-doped carbon nanotube sponges (N-CNS) was obtained at 1020 °C with 4 h of growth in an aerosol-assisted chemical vapor deposition…”
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CEP55 is a determinant of cell fate during perturbed mitosis in breast cancer by Kalimutho, Murugan, Sinha, Debottam, Jeffery, Jessie, Nones, Katia, Srihari, Sriganesh, Fernando, Winnie C, Duijf, Pascal HG, Vennin, Claire, Raninga, Prahlad, Nanayakkara, Devathri, Mittal, Deepak, Saunus, Jodi M, Lakhani, Sunil R, López, J Alejandro, Spring, Kevin J, Timpson, Paul, Gabrielli, Brian, Waddell, Nicola, Khanna, Kum Kum

“…The centrosomal protein, CEP55, is a key regulator of cytokinesis, and its overexpression is linked to genomic instability, a hallmark of cancer. However, the…”
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Two Sprayer CVD Synthesis of Nitrogen-doped Carbon Sponge-type Nanomaterials by Muñoz-Sandoval, Emilio, Fajardo-Díaz, Juan L., Sánchez-Salas, Roque, Cortés-López, Alejandro J., López-Urías, Florentino

“…Nitrogen-doped carbon sponge-type nanostructures (N-CSTNs) containing coaxial multiwalled carbon nanotubes are synthesized at 1020 °C by using a modified…”
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Carbon sponge-type nanostructures based on coaxial nitrogen-doped multiwalled carbon nanotubes grown by CVD using benzylamine as precursor by Muñoz-Sandoval, Emilio, Cortes-López, Alejandro J., Flores-Gómez, Beatriz, Fajardo-Díaz, Juan L., Sánchez-Salas, Roque, López-Urías, Florentino

“…Carbon sponges-type nanostructures (CSTN) based on coaxial nitrogen-doped multiwalled carbon nanotubes (CA-MWCNTs) were synthesized using the aerosol assisted…”
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Apoptosis and dysfunction of blood dendritic cells in patients with falciparum and vivax malaria by Pinzon-Charry, Alberto, Woodberry, Tonia, Kienzle, Vivian, McPhun, Virginia, Minigo, Gabriela, Lampah, Daniel A, Kenangalem, Enny, Engwerda, Christian, López, J Alejandro, Anstey, Nicholas M, Good, Michael F

“…Malaria causes significant morbidity worldwide and a vaccine is urgently required. Plasmodium infection causes considerable immune dysregulation, and…”
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Breast cancer stem cells: treatment resistance and therapeutic opportunities by AL-EJEH, Fares, SMART, Chanel E, MORRISON, Brian J, CHENEVIX-TRENCH, Georgia, LOPEZ, J. Alejandro, LAKHANI, Sunil R, BROWN, Michael P, KUM KUM KHANNA

“…The clinical and pathologic heterogeneity of human breast cancer has long been recognized. Now, molecular profiling has enriched our understanding of breast…”
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Antigens for cancer immunotherapy by Neller, Michelle A, López, J. Alejandro, Schmidt, Christopher W

“…Abstract Progress in tumor immunology has not been translated to effective immunotherapies for cancer. Most of the current effort in basic and clinical…”
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Dendritic cell dysfunction in cancer: A mechanism for immunosuppression by Pinzon‐Charry, Alberto, Maxwell, Tammy, López, J Alejandro

“…Several reports have demonstrated that tumours are not intrinsically resistant to the immune response. However, neoplasias commonly fail to initiate and…”
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Oxygenated Surface of Carbon Nanotube Sponges: Electroactivity and Magnetic Studies by Cortés-López, Alejandro J, Muñoz-Sandoval, Emilio, López-Urías, Florentino

“…We report the synthesis of nitrogen-doped carbon nanotube sponges (N-CNSs) by pyrolysis of solutions of benzylamine, ferrocene, thiophene, and…”
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Response of estrogen receptor-positive breast cancer tumorspheres to antiestrogen treatments by Ao, Ada, Morrison, Brian J, Wang, Heiman, López, J Alejandro, Reynolds, Brent A, Lu, Jianrong

“…Estrogen signaling plays a critical role in the pathogenesis of breast cancer. Because the majority of breast carcinomas express the estrogen receptor ERα,…”
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Edge Chemistry of Armchair Graphene Nanoribbons Containing Sulfur Functional Groups: Towards an Understanding of the Spin‐Dependent Electrochemistry by López‐Urías, Florentino, Fajardo‐Díaz, Juan L., Cortés‐López, Alejandro J., Rodríguez‐Corvera, Cristina L., Jiménez‐Ramírez, Luis E., Muñoz‐Sandoval, Emilio

“…Numerous sulfur functional groups (35) attached to the edges of armchair graphene nanoribbons are investigated through the use of quantum mechanical…”
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Spontaneous generation and survival of blood dendritic cells in mononuclear cell culture without exogenous cytokines by Ho, Christopher S.K., Munster, David, Pyke, Christopher M., Hart, Derek N.J., López, J. Alejandro

“…Studies on purified blood dendritic cells (DCs) are hampered by poor viability in tissue culture. We, therefore, attempted to study some of the…”
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Hemispherotomy for pediatric epilepsy: a systematic review and critical analysis by Lopez, Alejandro J., Badger, Clint, Kennedy, Benjamin C.

“…Purpose Several variations of functional disconnection surgery have been described for the treatment of lateralized, hemispheric, drug-resistant epilepsy in…”
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Cep55 overexpression causes male‐specific sterility in mice by suppressing Foxo1 nuclear retention through sustained activation of PI3K/Akt signaling by Sinha, Debottam, Kalimutho, Murugan, Bowles, Josephine, Chan, Ai-Leen, Merriner, D. Jo, Bain, Amanda L., Simmons, Jacinta L., Freire, Raimundo, Lopez, J. Alejandro, Hobbs, Robin M., O'Bryan, Moira K., Khanna, Kum Kum

“…ABSTRACT Spermatogenesis is a dynamic process involving self‐renewal and differentiation of spermatogonial stem cells, meiosis, and ultimately, the…”
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Spin-dependent band-gap driven by nitrogen and oxygen functional groups in zigzag graphene nanoribbons by López-Urías, Florentino, Fajardo-Díaz, Juan L., Cortés-López, Alejandro J., Rodríguez-Corvera, Cristina L., Jiménez-Ramírez, Luis E., Muñoz-Sandoval, Emilio

“…[Display omitted] •It was found that the magnetic ordering is affected by the functional groups.•It was investigated the injection or extraction of electrons…”
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Anatomy and biomechanics of the craniovertebral junction by Lopez, Alejandro J, Scheer, Justin K, Leibl, Kayla E, Smith, Zachary A, Dlouhy, Brian J, Dahdaleh, Nader S

“…The craniovertebral junction (CVJ) has unique anatomical structures that separate it from the subaxial cervical spine. In addition to housing vital neural and…”
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Cep55 regulation of PI3K/Akt signaling is required for neocortical development and ciliogenesis by Rashidieh, Behnam, Shohayeb, Belal, Bain, Amanda Louise, Fortuna, Patrick R. J, Sinha, Debottam, Burgess, Andrew, Mills, Richard, Adams, Rachael C, Lopez, J. Alejandro, Blumbergs, Peter, Finnie, John, Kalimutho, Murugan, Piper, Michael, Hudson, James Edward, Ng, Dominic C. H, Khanna, Kum Kum

“…Homozygous nonsense mutations in CEP55 are associated with several congenital malformations that lead to perinatal lethality suggesting that it plays a…”
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Immunological Responses to Envenomation by Ryan, Rachael Y M, Seymour, Jamie, Loukas, Alex, Lopez, J Alejandro, Ikonomopoulou, Maria P, Miles, John J

“…Venoms are complex mixtures of toxic compounds delivered by bite or sting. In humans, the consequences of envenomation range from self-limiting to lethal…”
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Single cell transcriptomics shows that malaria promotes unique regulatory responses across multiple immune cell subsets by Dooley, Nicholas L., Chabikwa, Tinashe G., Pava, Zuleima, Loughland, Jessica R., Hamelink, Julianne, Berry, Kiana, Andrew, Dean, Soon, Megan S. F., SheelaNair, Arya, Piera, Kim A., William, Timothy, Barber, Bridget E., Grigg, Matthew J., Engwerda, Christian R., Lopez, J. Alejandro, Anstey, Nicholas M., Boyle, Michelle J.

“…Plasmodium falciparum malaria drives immunoregulatory responses across multiple cell subsets, which protects from immunopathogenesis, but also hampers the…”
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