Search Results - "López, David J."

The effect of natural and synthetic fatty acids on membrane structure, microdomain organization, cellular functions and human health by Ibarguren, Maitane, López, David J., Escribá, Pablo V.

“…This review deals with the effects of synthetic and natural fatty acids on the biophysical properties of membranes, and on their implication on cell function…”
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Nucleophosmin, a multifunctional nucleolar organizer with a role in DNA repair by López, David J., Rodríguez, José A., Bañuelos, Sonia

“…Nucleophosmin (NPM1) is a mostly nucleolar protein with crucial functions in cell growth and homeostasis, including regulation of ribosome biogenesis and…”
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Molecular Mechanisms Regulating the DNA Repair Protein APE1: A Focus on Its Flexible N-Terminal Tail Domain by López, David J., Rodríguez, José A., Bañuelos, Sonia

“…APE1 (DNA (apurinic/apyrimidinic site) endonuclease 1) is a key enzyme of one of the major DNA repair routes, the BER (base excision repair) pathway. APE1…”
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Markups, Gaps, and the Welfare Costs of Business Fluctuations by Galí, Jordi, Gertler, Mark, López-Salido, J. David

“…We present a simple theory-based measure of the variations in aggregate economic efficiency: the gap between the marginal product of labor and the household's…”
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About a dubious proof of a correct result about closed Newton Cotes error formulas by López, David J., Padilla, Jose A., Ruiz, Juan, Tapia, Carlos, Trillo, Juan C.

“…In this study, we comment about a wrong proof, at least incomplete, of the closed Newton Cotes error formulas for integration in a closed interval [ a , b ] …”
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Partitioning of liquid-ordered/liquid-disordered membrane microdomains induced by the fluidifying effect of 2-hydroxylated fatty acid derivatives by Ibarguren, Maitane, López, David J., Encinar, José A., González-Ros, José M., Busquets, Xavier, Escribá, Pablo V.

“…Cellular functions are usually associated with the activity of proteins and nucleic acids. Recent studies have shown that lipids modulate the localization and…”
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Membrane lipid modifications and therapeutic effects mediated by hydroxydocosahexaenoic acid on Alzheimer's disease by Torres, Manuel, Price, Samantha L., Fiol-deRoque, Maria A., Marcilla-Etxenike, Amaia, Ahyayauch, Hasna, Barceló-Coblijn, Gwendolyn, Terés, Silvia, Katsouri, Loukia, Ordinas, Margarita, López, David J., Ibarguren, Maitane, Goñi, Félix M., Busquets, Xavier, Vitorica, Javier, Sastre, Magdalena, Escribá, Pablo V.

“…Alzheimer's disease (AD) is a neurodegenerative pathology with relevant unmet therapeutic needs. Both natural aging and AD have been associated with a…”
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The effect of hydroxylated fatty acid-containing phospholipids in the remodeling of lipid membranes by Piotto, Stefano, Trapani, Alfonso, Bianchino, Erminia, Ibarguren, Maitane, López, David J., Busquets, Xavier, Concilio, Simona

“…The synthetic fatty acid 2-hydroxyoleic acid (2OHOA) is an antitumor drug that regulates membrane lipid composition and structure. An important effect of this…”
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Nucleophosmin interaction with APE1: Insights into DNA repair regulation by López, David J., de Blas, Ander, Hurtado, Mikel, García-Alija, Mikel, Mentxaka, Jon, de la Arada, Igor, Urbaneja, María A., Alonso-Mariño, Marián, Bañuelos, Sonia

“…NPM1 (pentameric, with core domain depicted in blue and C-terminal domains in yellow) can bind several molecules of APE1 (green) and compete with the…”
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Effects of a 10-week running-retraining programme on the foot strike pattern of adolescents: A longitudinal intervention study by Consuegra González, Pedro José, García-Pinillos, Felipe, Mora López, David J., Cardona Linares, Antonio José, Párraga Montilla, Juan Antonio, Latorre-Román, Pedro Ángel

“…•Intervention: pretest-postest-retest.•Longitudinal training.•Foot strike pattern analysis. The purpose of this study was to analyse the effects of ten weeks…”
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G protein-membrane interactions II: Effect of G protein-linked lipids on membrane structure and G protein-membrane interactions by Casas, Jesús, Ibarguren, Maitane, Álvarez, Rafael, Terés, Silvia, Lladó, Victoria, Piotto, Stefano P., Concilio, Simona, Busquets, Xavier, López, David J., Escribá, Pablo V.

“…G proteins often bear myristoyl, palmitoyl and isoprenyl moieties, which favor their association with the membrane and their accumulation in G Protein Coupled…”
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Conformational stabilization as a strategy to prevent nucleophosmin mislocalization in leukemia by Urbaneja, María A., Skjærven, Lars, Aubi, Oscar, Underhaug, Jarl, López, David J., Arregi, Igor, Alonso-Mariño, Marián, Cuevas, Andoni, Rodríguez, José A., Martinez, Aurora, Bañuelos, Sonia

“…Nucleophosmin (NPM) is a nucleolar protein involved in ribosome assembly and cell homeostasis. Mutations in the C-terminal domain of NPM that impair native…”
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The hydroxylated form of docosahexaenoic acid (DHA-H) modifies the brain lipid composition in a model of Alzheimer's disease, improving behavioral motor function and survival by Mohaibes, Raheem J., Fiol-deRoque, María A., Torres, Manuel, Ordinas, Margarita, López, David J., Castro, José A., Escribá, Pablo V., Busquets, Xavier

“…We have compared the effect of the commonly used ω-3 fatty acid, docosahexaenoic acid ethyl ester (DHA-EE), and of its 2-hydroxylated DHA form (DHA-H), on…”
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Triacylglycerol mimetics regulate membrane interactions of glycogen branching enzyme: implications for therapy by Alvarez, Rafael, Casas, Jesús, López, David J., Ibarguren, Maitane, Suari-Rivera, Ariadna, Terés, Silvia, Guardiola-Serrano, Francisca, Lossos, Alexander, Busquets, Xavier, Kakhlon, Or, Escribá, Pablo V.

“…Adult polyglucosan body disease (APBD) is a neurological disorder characterized by adult-onset neurogenic bladder, spasticity, weakness, and sensory loss. The…”
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Effect of Different N:P Ratios on the Growth, Toxicity, and Toxin Profile of Gymnodinium catenatum (Dinophyceae) Strains from the Gulf of California by Hernández-Sandoval, Francisco E, Bustillos-Guzmán, José J, Band-Schmidt, Christine J, Núñez-Vázquez, Erick J, López-Cortés, David J, Fernández-Herrera, Leyberth J, Poot-Delgado, Carlos A, Moreno-Legorreta, Manuel

“…The harmful microalgae is a unique naked dinoflagellate that produces paralytic shellfish poisoning toxins (PSTs). This species is common along the coasts of…”
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The Federal Reserve's Framework for Monetary Policy: Recent Changes and New Questions by ENGLISH, WILLIAM B., LÓPEZ-SALIDO, J. DAVID, TETLOW, ROBERT J.

“…The Federal Reserve has made substantial changes to its framework for monetary policy in recent years. On balance, the Federal Reserve has moved closer to the…”
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Changes in Membrane Organization upon Spontaneous Insertion of 2‑Hydroxylated Unsaturated Fatty Acids in the Lipid Bilayer by Khmelinskaia, Alena, Ibarguren, Maitane, de Almeida, Rodrigo F. M, López, David J, Paixão, Vanda A, Ahyayauch, Hasna, Goñi, Félix M, Escribá, Pablo V

“…Recent research regarding 2-hydroxylated fatty acids (2OHFAs) showed clear evidence of their benefits in the treatment of cancer, inflammation, and…”
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Ceramide-Enriched Membrane Domains in Red Blood Cells and the Mechanism of Sphingomyelinase-Induced Hot−Cold Hemolysis by Montes, L.-Ruth, López, David J, Sot, Jesús, Bagatolli, Luis A, Stonehouse, Martin J, Vasil, Michael L, Wu, Bill X, Hannun, Yusuf A, Goñi, Félix M, Alonso, Alicia

“…Hot−cold hemolysis is the phenomenon whereby red blood cells, preincubated at 37 °C in the presence of certain agents, undergo rapid hemolysis when transferred…”
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Lipophilic Toxins in Wild Bivalves from the Southern Gulf of California, Mexico by Leyva-Valencia, Ignacio, Hernández-Castro, Jesús Ernestina, Band-Schmidt, Christine J, Turner, Andrew D, O'Neill, Alison, Núñez-Vázquez, Erick J, López-Cortés, David J, Bustillos-Guzmán, José J, Hernández-Sandoval, Francisco E

“…Most of the shellfish fisheries of Mexico occur in the Gulf of California. In this region, known for its high primary productivity, blooms of diatoms and…”
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Differential effect of 2-hydroxyoleic acid enantiomers on protein (sphingomyelin synthase) and lipid (membrane) targets by Piotto, Stefano, Concilio, Simona, Bianchino, Erminia, Iannelli, Pio, López, David J., Terés, Silvia, Ibarguren, Maitane, Barceló-Coblijn, Gwendolyn, Martin, Maria Laura, Guardiola-Serrano, Francisca, Alonso-Sande, María, Funari, Sérgio S., Busquets, Xavier, Escribá, Pablo V.

“…The complex dual mechanism of action of 2-hydroxyoleic acid (2OHOA), a potent anti-tumor compound used in membrane lipid therapy (MLT), has yet to be fully…”
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