Search Results - "Lévèque, Nicolas"
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Alarmin S100A9 restricts retroviral infection by limiting reverse transcription in human dendritic cells
Published in The EMBO journal (16-08-2021)“…Dendritic cells (DC) subsets, like Langerhans cells (LC), are immune cells involved in pathogen sensing. They express specific antimicrobial cellular factors…”
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Usutu Virus escapes langerin-induced restriction to productively infect human Langerhans cells, unlike West Nile virus
Published in Emerging microbes & infections (31-12-2022)“…Usutu virus (USUV) and West Nile virus (WNV) are phylogenetically close emerging arboviruses and constitute a global public health threat. Since USUV and WNV…”
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Eczema Herpeticum: Clinical and Pathophysiological Aspects
Published in Clinical reviews in allergy & immunology (01-08-2020)“…Atopic dermatitis (AD) is the most common chronic inflammatory skin disease in the world. AD is a complex pathology mainly characterized by an impaired skin…”
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Antiviral and Immunomodulatory Properties of Antimicrobial Peptides Produced by Human Keratinocytes
Published in Frontiers in microbiology (03-06-2020)“…Keratinocytes, the main cells of the epidermis, are the first site of replication as well as the first line of defense against many viruses such as…”
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Skin innate immune response to flaviviral infection
Published in European cytokine network (01-06-2017)“…Skin is a complex organ and the largest interface of the human body exposed to numerous stress and pathogens. Skin is composed of different cell types that…”
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The Antiviral Activities of Poly-ADP-Ribose Polymerases
Published in Viruses (30-03-2021)“…The poly-adenosine diphosphate (ADP)-ribose polymerases (PARPs) are responsible for ADP-ribosylation, a reversible post-translational modification involved in…”
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VOC-Based Probes, a New Set of Analytical Tools to Monitor Patient Health from Blood Sample. Proof of Concept on Tracking COVID-19 Infection
Published in Analytical chemistry (Washington) (08-08-2023)“…Induced volatolomics is an emerging field that holds promise for many biomedical applications including disease detection and prognosis. In this pilot study,…”
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Skin tropism during Usutu virus and West Nile virus infection: an amplifying and immunological role
Published in Journal of virology (23-01-2024)“…Usutu virus (USUV) and West Nile virus (WNV) are closely related emerging arboviruses belonging to the genus and posing global public health concerns. Although…”
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Anti-SARS-CoV-2 Activity of Polysaccharides Extracted from Halymenia floresii and Solieria chordalis (Rhodophyta)
Published in Marine drugs (06-06-2023)“…Even after hundreds of clinical trials, the search for new antivirals to treat COVID-19 is still relevant. Carrageenans are seaweed sulfated polysaccharides…”
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A 21st century perspective of poliovirus replication
Published in PLoS pathogens (01-06-2015)“… Why Poliovirus Replication Must Still Be Studied Despite a dramatic reduction in the number of cases of poliomyelitis (350,000 cases in 1988 versus 416 cases…”
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Rapid Detection of Respiratory Tract Viral Infections and Coinfections in Patients with Influenza-Like Illnesses by Use of Reverse Transcription-PCR DNA Microarray Systems
Published in Journal of Clinical Microbiology (01-11-2010)“…We prospectively tested 95 nasal swabs or nasopharyngeal aspirates taken from 56 adults and 39 children visiting the Reims University Medical Centre (northern…”
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Enterovirus Persistence in Cardiac Cells of Patients With Idiopathic Dilated Cardiomyopathy Is Linked to 5’ Terminal Genomic RNA-Deleted Viral Populations With Viral-Encoded Proteinase Activities
Published in Circulation (New York, N.Y.) (14-05-2019)“…BACKGROUND:Group B enteroviruses are common causes of acute myocarditis, which can be a precursor of chronic myocarditis and dilated cardiomyopathy, leading…”
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Antiviral Effect of hBD-3 and LL-37 during Human Primary Keratinocyte Infection with West Nile Virus
Published in Viruses (15-07-2022)“…West Nile virus (WNV) is an emerging flavivirus transmitted through mosquito bites and responsible for a wide range of clinical manifestations. Following their…”
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Merkel cell carcinoma: histopathologic and prognostic features according to the immunohistochemical expression of Merkel cell polyomavirus large T antigen correlated with viral load
Published in Human pathology (01-03-2015)“…Summary Merkel cell carcinoma (MCC) is a neuroendocrine skin malignancy frequently associated with Merkel cell polyomavirus (MCPyV), which is suspected to be…”
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Comparison of Anti-Viral Activity of Frog Skin Anti-Microbial Peptides Temporin-Sha and [K³]SHa to LL-37 and Temporin-Tb against Herpes Simplex Virus Type 1
Published in Viruses (01-01-2019)“…Temporins are anti-microbial peptides synthesized in the skin of frogs of the family. The few studies to date that have examined their anti-viral properties…”
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Characterization of a new case of XMLV (Bxv1) contamination in the human cell line Hep2 (clone 2B)
Published in Scientific reports (29-09-2020)“…The use of misidentified cell lines contaminated by other cell lines and/or microorganisms has generated much confusion in the scientific literature. Detailed…”
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Viral causes of human myocarditis
Published in Archives of cardiovascular diseases (01-06-2009)“…Summary The diagnosis of acute myocarditis is complex and challenging. The use of the Dallas criteria in the diagnosis of myocarditis is associated with poor…”
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Cytoplasmic relocalization of heterogeneous nuclear ribonucleoprotein A1 controls translation initiation of specific mRNAs
Published in Molecular biology of the cell (01-12-2007)“…Heterogeneous nuclear ribonucleoprotein (hnRNP) A1 is a nucleocytoplasmic shuttling protein that regulates gene expression through its action on mRNA…”
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One year of SARS-CoV-2 circulation in the Nouvelle-Aquitaine region, February 2021-2022, France
Published in Frontiers in microbiology (28-07-2023)“…Since 2021, 3 variants of concern (VOC) have spread to France, causing successive epidemic waves. To describe the features of Alpha, Delta and Omicron VOC…”
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