Search Results - "Léna, Clément"

Bidirectional control of fear memories by cerebellar neurons projecting to the ventrolateral periaqueductal grey by Frontera, Jimena Laura, Baba Aissa, Hind, Sala, Romain William, Mailhes-Hamon, Caroline, Georgescu, Ioana Antoaneta, Léna, Clément, Popa, Daniela

“…Fear conditioning is a form of associative learning that is known to involve different brain areas, notably the amygdala, the prefrontal cortex and the…”
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When the cerebellum holds the starting gun by Frontera, Jimena L., Léna, Clément

“…How the cerebellum affects movement onset is poorly understood. In this issue of Neuron, Dacre et al. (2021) establish that in the context of operant…”
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Cerebellum involvement in cortical sensorimotor circuits for the control of voluntary movements by Proville, Rémi D, Spolidoro, Maria, Guyon, Nicolas, Dugué, Guillaume P, Selimi, Fekrije, Isope, Philippe, Popa, Daniela, Léna, Clément

“…The authors identify a region in the cerebellar cortex where sensory and motor information from the neocortex converge. Activation of this region modifies…”
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Coherent amygdalocortical theta promotes fear memory consolidation during paradoxical sleep by Popa, Daniela, Duvarci, Sevil, Popescu, Andrei T, Léna, Clément, Paré, Denis

“…Brain activity in sleep plays a crucial role in memory consolidation, an offline process that determines the long-term strength of memory traces. Consolidation…”
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Clusters of cerebellar Purkinje cells control their afferent climbing fiber discharge by Chaumont, Joseph, Guyon, Nicolas, Valera, Antoine M., Dugué, Guillaume P., Popa, Daniela, Marcaggi, Paikan, Gautheron, Vanessa, Reibel-Foisset, Sophie, Dieudonné, Stéphane, Stephan, Aline, Barrot, Michel, Cassel, Jean-Christophe, Dupont, Jean-Luc, Doussau, Frédéric, Poulain, Bernard, Selimi, Fekrije, Léna, Clément, Isope, Philippe

“…Climbing fibers, the projections from the inferior olive to the cerebellar cortex, carry sensorimotor error and clock signals that trigger motor learning by…”
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The cerebellum regulates fear extinction through thalamo-prefrontal cortex interactions in male mice by Frontera, Jimena L., Sala, Romain W., Georgescu, Ioana A., Baba Aissa, Hind, d’Almeida, Marion N., Popa, Daniela, Léna, Clément

“…Fear extinction is a form of inhibitory learning that suppresses the expression of aversive memories and plays a key role in the recovery of anxiety and…”
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A novel inhibitory nucleo-cortical circuit controls cerebellar Golgi cell activity by Ankri, Lea, Husson, Zoé, Pietrajtis, Katarzyna, Proville, Rémi, Léna, Clément, Yarom, Yosef, Dieudonné, Stéphane, Uusisaari, Marylka Yoe

“…The cerebellum, a crucial center for motor coordination, is composed of a cortex and several nuclei. The main mode of interaction between these two parts is…”
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Time‐invariant feed‐forward inhibition of Purkinje cells in the cerebellar cortex in vivo by Blot, Antonin, Solages, Camille, Ostojic, Srdjan, Szapiro, German, Hakim, Vincent, Léna, Clément

“…Key points We performed extracellular recording of pairs of interneuron–Purkinje cells in vivo. A single interneuron produces a substantial, short‐lasting,…”
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Functional role of the cerebellum in gamma-band synchronization of the sensory and motor cortices by Popa, Daniela, Spolidoro, Maria, Proville, Rémi D, Guyon, Nicolas, Belliveau, Lucile, Léna, Clément

“…The cerebellum is an essential structure for the control of movement. It sends abundant ascending projections to the cerebral cortex via the thalamus, but its…”
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Cerebellar stimulation prevents Levodopa-induced dyskinesia in mice and normalizes activity in a motor network by Coutant, Bérénice, Frontera, Jimena Laura, Perrin, Elodie, Combes, Adèle, Tarpin, Thibault, Menardy, Fabien, Mailhes-Hamon, Caroline, Perez, Sylvie, Degos, Bertrand, Venance, Laurent, Léna, Clément, Popa, Daniela

“…Chronic Levodopa therapy, the gold-standard treatment for Parkinson’s Disease (PD), leads to the emergence of involuntary movements, called levodopa-induced…”
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Functional Alteration of Cerebello-Cerebral Coupling in an Experimental Mouse Model of Parkinson's Disease by Menardy, Fabien, Varani, Andrés Pablo, Combes, Adèle, Léna, Clément, Popa, Daniela

“…Abstract In Parkinson's disease, the degeneration of the midbrain dopaminergic neurons is consistently associated with modified metabolic activity in the…”
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Lasting Syndrome of Depression Produced by Reduction in Serotonin Uptake during Postnatal Development: Evidence from Sleep, Stress, and Behavior by Popa, Daniela, Lena, Clement, Alexandre, Chloe, Adrien, Joelle

“…Dysfunction of the serotonin system is implicated in sleep and emotional disorders. To test whether these impairments could arise during development, we…”
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Cerebellar re-encoding of self-generated head movements by Dugué, Guillaume P, Tihy, Matthieu, Gourévitch, Boris, Léna, Clément

“…Head movements are primarily sensed in a reference frame tied to the head, yet they are used to calculate self-orientation relative to the world. This requires…”
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Functional abnormalities in the cerebello-thalamic pathways in a mouse model of DYT25 dystonia by Aïssa, Hind Baba, Sala, Romain W, Georgescu Margarint, Elena Laura, Frontera, Jimena Laura, Varani, Andrés Pablo, Menardy, Fabien, Pelosi, Assunta, Hervé, Denis, Léna, Clément, Popa, Daniela

“…Dystonia is often associated with functional alterations in the cerebello-thalamic pathways, which have been proposed to contribute to the disorder by…”
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T-type channel blockade impairs long-term potentiation at the parallel fiber–Purkinje cell synapse and cerebellar learning by Ly, Romain, Bouvier, Guy, Schonewille, Martijn, Arabo, Arnaud, Rondi-Reig, Laure, Léna, Clément, Casado, Mariano, De Zeeuw, Chris I., Feltz, Anne

“…Ca V3.1 T-type channels are abundant at the cerebellar synapse between parallel fibers and Purkinje cells where they contribute to synaptic depolarization. So…”
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High-Frequency Organization and Synchrony of Activity in the Purkinje Cell Layer of the Cerebellum by de Solages, Camille, Szapiro, Germán, Brunel, Nicolas, Hakim, Vincent, Isope, Philippe, Buisseret, Pierre, Rousseau, Charly, Barbour, Boris, Léna, Clément

“…The cerebellum controls complex, coordinated, and rapid movements, a function requiring precise timing abilities. However, the network mechanisms that underlie…”
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Cerebellar control of fear learning via the cerebellar nuclei-Multiple pathways, multiple mechanisms? by Urrutia Desmaison, Julie D, Sala, Romain W, Ayyaz, Ahsan, Nondhalee, Pimpimon, Popa, Daniela, Léna, Clément

“…Fear learning is mediated by a large network of brain structures and the understanding of their roles and interactions is constantly progressing. There is a…”
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Microglial TNFα controls daily changes in synaptic GABAARs and sleep slow waves by Pinto, Maria Joana, Bizien, Lucy, Fabre, Julie M J, Ðukanović, Nina, Lepetz, Valentin, Henderson, Fiona, Pujol, Marine, Sala, Romain W, Tarpin, Thibault, Popa, Daniela, Triller, Antoine, Léna, Clément, Fabre, Véronique, Bessis, Alain

“…Microglia sense the changes in their environment. How microglia actively translate these changes into suitable cues to adapt brain physiology is unknown. We…”
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Burst-Dependent Bidirectional Plasticity in the Cerebellum Is Driven by Presynaptic NMDA Receptors by Bouvier, Guy, Higgins, David, Spolidoro, Maria, Carrel, Damien, Mathieu, Benjamin, Léna, Clément, Dieudonné, Stéphane, Barbour, Boris, Brunel, Nicolas, Casado, Mariano

“…Numerous studies have shown that cerebellar function is related to the plasticity at the synapses between parallel fibers and Purkinje cells. How specific…”
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Electrical Coupling Mediates Tunable Low-Frequency Oscillations and Resonance in the Cerebellar Golgi Cell Network by Dugué, Guillaume P., Brunel, Nicolas, Hakim, Vincent, Schwartz, Eric, Chat, Mireille, Lévesque, Maxime, Courtemanche, Richard, Léna, Clément, Dieudonné, Stéphane

“…Tonic motor control involves oscillatory synchronization of activity at low frequency (5–30 Hz) throughout the sensorimotor system, including cerebellar areas…”
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