Search Results - "Lébl, M"

Using support vector machine regression to model the retention of peptides in immobilized metal-affinity chromatography by Kermani, B.G., Kozlov, I., Melnyk, P., Zhao, C., Hachmann, J., Barker, D., Lebl, M.

“…Retention of histidine-containing peptides in immobilized metal-affinity chromatography (IMAC) has been studied using several hundred model peptides. Retention…”
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Absorption bands of lead in alkali chlorides in the presence of hydroxyl ions by Lébl, M.

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Enzyme-Mediated Spatial Segregation on Individual Polymeric Support Beads: Application to Generation and Screening of Encoded Combinatorial Libraries by Vágner, Josef, Barany, George, Lam, Kit S., Krchn̆ák, Viktor, Sepetov, Nikolai F., Ostrem, James A., Strop, Peter, Lebl, Michal

“…Proteolysis of short Nα-protected peptide substrates bound to polyoxyethylene-polystyrene beads releases selectively free amino sites in the enzyme-accessible…”
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Synthesis of a one-bead one-compound combinatorial peptide library by Lam, K S, Lebl, M

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Discovery of Biologically Active Peptides in Random Libraries: Solution- Phase Testing After Staged Orthogonal Release from Resin Beads by Salmon, Sydney E., Lam, Kit S., Lebl, Michal, Kandola, Anitha, Khattri, Parth S., Wade, Shelly, Patek, Marcel, Kocis, Petr, Krchnak, Viktor, Thorpe, David, Felder, Stephen

“…To speed drug discovery, we developed an approach for identification of individual peptides with a desired biological activity from a library containing…”
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On the question of Bi(III) complexes in NaCl by Trnka, J., Lébl, M.

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Visible and near-infrared absorption of LiCl crystal with divalent nickel by Polák, K., Lébl, M.

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Synthetic library techniques: subjective (biased and generic) thoughts and views by Krchnák, V, Lebl, M

“…Various aspects of synthetic diversity generation and screening are discussed. Controversial issues are raised and different points of view are presented. We…”
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One bead-one compound combinatorial peptide library: different types of screening by Chen, C L, Strop, P, Lebl, M, Lam, K S

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Library of Libraries: Approach to Synthetic Combinatorial Library Design and Screening of "Pharmacophore" Motifs by Sepetov, Nikolai F., Krchnak, Viktor, Stankova, Magda, Wade, Shelly, Lam, Kit S., Lebl, Michal

“…Construction of synthetic combinatorial libraries is described that allows for the generation of a library of motifs rather than a library of compounds…”
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Structurally homogeneous and heterogeneous synthetic combinatorial libraries by Krchnák, V, Weichsel, A S, Cabel, D, Flegelova, Z, Lebl, M

“…We have designed and synthesized structurally homogeneous and heterogeneous nonpeptide libraries. Structurally homogeneous libraries are characterized by the…”
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Parallel personal comments on "classical" papers in combinatorial chemistry by Lebl, M

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Z-like-centers in vanadium doped NaCl crystals by Polák, K., Bohun, A., Lébl, M.

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To the vibronic structure of MnO 4 − ions by Bohun, A., Pračka, M., Lébl, M.

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The “One-Bead-One-Compound” Combinatorial Library Method by Lam, Kit S, Lebl, Michal, Krchňák, Viktor

“…Lam et al give a brief description of the one-bead-one-compound concept and a detailed account of the chemistry used for library synthesis, various screening…”
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Flow stress in NaCl: BaCl2 single crystals by Grau, P., HartmanovÁ, M., Lébl, M.

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The absorption of cupric halides by Bohun, A., Lébl, M., Rozsíval, M.

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Haemodynamics and the participation of pressor systems in young and adult rats with age-dependent DOCA-salt hypertension by Zicha, J, Kunes, J, Lébl, M, Pohlová, I, Jelínek, J

“…Increased systemic resistance is the main haemodynamic abnormality in DOCA-salt hypertension which is more pronounced in young than in adult rats. A mild…”
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Antidiuretic and pressor actions of vasopressin in age-dependent DOCA-salt hypertension by Zicha, J, Kunes, J, Lébl, M, Pohlová, I, Slaninová, J, Jelínek, J

“…The role of antidiuretic and pressor effects of vasopressin (VP) in deoxycorticosterone acetate (DOCA)-salt hypertension was studied in young and adult…”
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Search for optimal coupling reagent in multiple peptide synthesizer by Hachmann, John, Lebl, Michal

“…Ten different coupling reagents and their combinations were tested in parallel in the synthesis of four model peptide sequences. Significant differences were…”
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