Search Results - "Lázcoz, Paula"

Detection of methylation in promoter sequences by melting curve analysis-based semiquantitative real time PCR by Lorente, Aiala, Mueller, Wolf, Urdangarín, Edurne, Lázcoz, Paula, von Deimling, Andreas, Castresana, Javier S

“…We present two melting curve analysis (MCA)-based semiquantitative real time PCR techniques to detect the promoter methylation status of genes. The first,…”
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Frequent promoter hypermethylation of RASSF1A and CASP8 in neuroblastoma by Lázcoz, Paula, Muñoz, Jorge, Nistal, Manuel, Pestaña, Angel, Encío, Ignacio, Castresana, Javier S

“…Epigenetic alterations and loss of heterozygosity are mechanisms of tumor suppressor gene inactivation. A new carcinogenic pathway, targeting the RAS effectors…”
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RASSF1A, BLU, NORE1A, PTEN and MGMT Expression and Promoter Methylation in Gliomas and Glioma Cell Lines and Evidence of Deregulated Expression of de novo DNMTs by Lorente, Aiala, Mueller, Wolf, Urdangarín, Edurne, Lázcoz, Paula, Lass, Ulrike, Von Deimling, Andreas, Castresana, Javier S.

“…Methylation of CpG islands in gene promoters can lead to gene silencing. Together with deletion or mutation, it may cause a loss of function of tumor…”
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Analysis of stemness gene expression and CD133 abnormal methylation in neuroblastoma cell lines by Schiapparelli, Paula, Enguita-Germán, Mónica, Balbuena, Jana, Rey, Juan A, Lázcoz, Paula, Castresana, Javier S

“…Neuroblastoma is the most common extracranial solid tumor in children, accounting for up to 10% of all childhood malignancies. Cellular heterogeneity is a…”
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In Vitro Assessment of the Role of p53 on Chemotherapy Treatments in Neuroblastoma Cell Lines by Blanco-Luquin, Idoia, Lázcoz, Paula, Celay, Jon, Castresana, Javier S., Encío, Ignacio J.

“…Neuroblastoma is the most frequent malignant extracranial solid tumor of infancy. The overall objective of this work consists of determining the presence of…”
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Homozygous deletion and expression of PTEN and DMBT1 in human primary neuroblastoma and cell lines by Muñoz, Jorge, Lázcoz, Paula, del Mar Inda, María, Nistal, Manuel, Pestaña, Angel, Encío, Ignacio J., Castresana, Javier S.

“…Neuroblastoma is the most common pediatric solid tumor. Although many allelic imbalances have been described, a bona fide tumor suppressor gene for this…”
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Changes in gene expression profiling of apoptotic genes in neuroblastoma cell lines upon retinoic acid treatment by Celay, Jon, Blanco, Idoia, Lázcoz, Paula, Rotinen, Mirja, Castresana, Javier S, Encío, Ignacio

“…To determine the effect of retinoic acid (RA) in neuroblastoma we treated RA sensitive neuroblastoma cell lines with 9-cis RA or ATRA for 9 days, or for 5 days…”
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Inhibition of the sonic hedgehog pathway by cyplopamine reduces the CD133+/CD15+ cell compartment and the in vitro tumorigenic capability of neuroblastoma cells by Schiapparelli, Paula, Shahi, Mehdi H, Enguita-Germán, Mónica, Johnsen, John Inge, Kogner, Per, Lázcoz, Paula, Castresana, Javier S

“…Highlights ► Sonic hedgehog inhibition by cyclopamine in neuroblastoma. ► Decrease of cell proliferation and tumorigenic potential. ► Decrease in percentage of…”
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Inhibition of the sonic hedgehog pathway by cyplopamine reduces the CD133+/CD15+ cell compartment and thein vitrotumorigenic capability of neuroblastoma cells by Schiapparelli, Paula, Shahi, Mehdi H, Enguita-Germán, Mónica, Johnsen, John Inge, Kogner, Per, Lázcoz, Paula, Castresana, Javier S

“…Highlights * Sonic hedgehog inhibition by cyclopamine in neuroblastoma. * Decrease of cell proliferation and tumorigenic potential. * Decrease in percentage of…”
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Promoter Methylation of RASSF1A Associates to Adult Secondary Glioblastomas and Pediatric Glioblastomas by Muñoz, Jorge, Inda, María del Mar, Lázcoz, Paula, Zazpe, Idoya, Fan, Xing, Alfaro, Jorge, Tuñón, Teresa, Rey, Juan A., Castresana, Javier S.

“…While allelic losses and mutations of tumor suppressor genes implicated in the etiology of astrocytoma have been widely assessed, the role of epigenetics is…”
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Loss of heterozygosity and microsatellite instability on chromosome arm 10q in neuroblastoma by Lázcoz, Paula, Muñoz, Jorge, Nistal, Manuel, Pestaña, Ángel, Encío, Ignacio J, Castresana, Javier S

“…Abstract Tumor suppressor genes can be inactivated by various mechanisms, including promoter hypermethylation and loss of heterozygosity. We screened the 10q…”
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Abstract 5247: Analysis of stemness gene expression and CD133 abnormal methylation in neuroblastoma cell lines by Schiapparelli, Paula, Enguita, Monica, Balbuena, Jana, Fan, Xing, Lazcoz, Paula, Castresana, Javier S.

“…Abstract Neuroblastoma is the most common extracranial solid tumor of childhood. Cellular heterogeneity is a hallmark of this embryonal malignancy, as distinct…”
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Abstract 3663: Effects of chemotherapy on cell survival, cell cycle biology and apoptosis in the SK-N-FI neuroblastoma cell line by Blanco, Idoia, Lazcoz, Paula, Celay, Jon, Fan, Xing, Castresana, Javier S., Encio, Ignacio J.

“…Abstract Neuroblastoma is a malignant embryonal childhood tumor of the peripheral nervous system, which often shows poor clinical prognosis. p53 mutations are…”
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Changes in Gene Expression Profiling of Apoptotic Genes in Neuroblastoma Cell Lines upon Retinoic Acid Treatment. e62771 by Celay, Jon, Blanco, Idoia, Lazcoz, Paula, Rotinen, Mirja, Castresana, Javier S, Encio, Ignacio

“…To determine the effect of retinoic acid (RA) in neuroblastoma we treated RA sensitive neuroblastoma cell lines with 9-cis RA or ATRA for 9 days, or for 5 days…”
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Analysis of stemness gene expression and CD133 abnormal methylation in neuroblastoma cell lines by SCHIAPPARELLI, Paula, ENGUITA-GERMAN, Mónica, BALBUENA, Jana, REY, Juan A, LAZCOZ, Paula, CASTRESANA, Javier S

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