Search Results - "LÜBBEN, Mathias"

Time-resolved spectroscopic and electrophysiological data reveal insights in the gating mechanism of anion channelrhodopsin by Dreier, Max-Aylmer, Althoff, Philipp, Norahan, Mohamad Javad, Tennigkeit, Stefan Alexander, El-Mashtoly, Samir F., Lübben, Mathias, Kötting, Carsten, Rudack, Till, Gerwert, Klaus

“…Channelrhodopsins are widely used in optogenetic applications. High photocurrents and low current inactivation levels are desirable. Two parallel photocycles…”
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Analytical Gel Filtration for Probing Heavy Metal Transfer between Proteins by Drees, Steffen, Lübben, Mathias

“…Heavy metals can cause damage to biomolecules such as proteins and DNA in multiple ways. Cells therefore strive for keeping intracellular (heavy) metal ions…”
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Bacteriorhodopsin's Intramolecular Proton-Release Pathway Consists of a Hydrogen-Bonded Network by Rammelsberg, Robin, Huhn, Gregor, Lübben, Mathias, Gerwert, Klaus

“…In its proton-pumping photocycle, bacteriorhodopsin releases a proton to the extracellular surface at pH 7 in the transition from intermediate L to…”
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Sulfate Acts as Phosphate Analog on the Monomeric Catalytic Fragment of the CPx-ATPase CopB from Sulfolobus solfataricus by Lübben, Mathias, Güldenhaupt, Jörn, Zoltner, Martin, Deigweiher, Katrin, Haebel, Peter, Urbanke, Claus, Scheidig, Axel J.

“…The crystal structure of the catalytic fragment of a Sulfolobus solfataricus P-type ATPase, CopB-B, was determined with a 2.6 Å resolution. CopB-B is the major…”
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The Active Site of the Bacterial Nitric Oxide Reductase Is a Dinuclear Iron Center by Hendriks, Janneke, Warne, Antony, Gohlke, Ulrich, Haltia, Tuomas, Ludovici, Claudia, Lübben, Mathias, Saraste, Matti

“…A novel, improved method for purification of nitric oxide reductase (NOR) from membranes of Paracoccus denitrificans has been developed. The purified enzyme is…”
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Cytochromes of archaeal electron transfer chains by Lübben, Mathias

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New Archaebacterial Genes Coding for Redox Proteins: Implications for the Evolution of Aerobic Metabolism by Castresana, Jose, Lübben, Mathias, Saraste, Matti

“…Archaebacterial respiratory chains are poorly understood at the molecular level. We have cloned and sequenced a cluster of five new genes from the…”
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Bacillus subtilis CtaA and CtaB function in haem A biosynthesis by Svensson, B, Lübben, M, Hederstedt, L

“…Haem A, a prosthetic group of many respiratory oxidases, is probably synthesized from haem B (protohaem IX) in a pathway in which haem O is an intermediate…”
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The Ras dimer structure by Rudack, Till, Teuber, Christian, Scherlo, Marvin, Güldenhaupt, Jörn, Schartner, Jonas, Lübben, Mathias, Klare, Johann, Gerwert, Klaus, Kötting, Carsten

“…Oncogenic mutated Ras is a key player in cancer, but despite intense and expensive approaches its catalytic center seems undruggable. The Ras dimer interface…”
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Redox FTIR difference spectroscopy using caged electrons reveals contributions of carboxyl groups to the catalytic mechanism of haemcopper oxidases by Lübben, Mathias, Gerwert, Klaus

“…Redox spectra of the haem-copper oxidases cytochrome aa 3 of Rhodobacter sphaeroides and cytochrome bo 3 of Escherichia coli were recorded in the visible and…”
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One gene, two proteins: coordinated production of a copper chaperone by differential transcript formation and translational frameshifting in Escherichia coli by Drees, Steffen L., Klinkert, Birgit, Helling, Stefan, Beyer, Dominik F., Marcus, Katrin, Narberhaus, Franz, Lübben, Mathias

“…Summary Programmed ribosomal frameshifting (PRF) is a translational anomaly causing the ribosome to shift into an alternative reading frame. PRFs are common in…”
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Distinct functions of serial metal-binding domains in the Escherichia coli P^sub 1B^-ATPase CopA by Drees, Steffen L, Beyer, Dominik F, Lenders-Lomscher, Christina, Lübben, Mathias

“…P1B-ATPases are among the most common resistance factors to metal-induced stress. Belonging to the superfamily of P-type ATPases, they are capable of exporting…”
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Distinct functions of serial metal‐binding domains in the Escherichia coli P1B‐ATPase CopA by Drees, Steffen L., Beyer, Dominik F., Lenders‐Lomscher, Christina, Lübben, Mathias

“…Summary P1B‐ATPases are among the most common resistance factors to metal‐induced stress. Belonging to the superfamily of P‐type ATPases, they are capable of…”
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Distinct functions of serial metal‐binding domains in the E scherichia coli   P 1 B ‐ ATP ase CopA by Drees, Steffen L., Beyer, Dominik F., Lenders‐Lomscher, Christina, Lübben, Mathias

“…Summary P 1 B ‐ ATP ases are among the most common resistance factors to metal‐induced stress. Belonging to the superfamily of P ‐type ATP ases, they are…”
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Cover Feature: Design of an Ultrafast G Protein Switch Based on a Mouse Melanopsin Variant (ChemBioChem 14/2019) by Tennigkeit, Stefan Alexander, Karapinar, Raziye, Rudack, Till, Dreier, Max‐Aylmer, Althoff, Philipp, Eickelbeck, Dennis, Surdin, Tatjana, Grömmke, Michelle, Mark, Melanie D., Spoida, Katharina, Lübben, Mathias, Höweler, Udo, Herlitze, Stefan, Gerwert, Klaus

“…The cover feature picture shows a structural model of the molecular light switch melanopsin symbolically placed in a mouse brain. Light absorption of…”
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The ATPases CopA and CopB both contribute to copper resistance of the thermoacidophilic archaeon Sulfolobus solfataricus by VÖLLMECKE, Christian, DREES, Steffen L, REIMANN, Julia, ALBERS, Sonja-Verena, LÜBBEN, Mathias

“…Certain heavy metal ions such as copper and zinc serve as essential cofactors of many enzymes, but are toxic at high concentrations. Thus, intracellular levels…”
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Design of an Ultrafast G Protein Switch Based on a Mouse Melanopsin Variant by Tennigkeit, Stefan Alexander, Karapinar, Raziye, Rudack, Till, Dreier, Max‐Aylmer, Althoff, Philipp, Eickelbeck, Dennis, Surdin, Tatjana, Grömmke, Michelle, Mark, Melanie D., Spoida, Katharina, Lübben, Mathias, Höweler, Udo, Herlitze, Stefan, Gerwert, Klaus

“…The primary goal of optogenetics is the light‐controlled noninvasive and specific manipulation of various cellular processes. Herein, we present a hybrid…”
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Caged O2 by Ludovici, Claudia, Fröhlich, Roland, Vogtt, Karsten, Mamat, Björn, Lübben, Mathias

“…We developed the synthesis of the caged oxygen donor (µ‐peroxo)(µ‐hydroxo)bis[bis(bipyridyl)cobalt(III)] complex (HPBC) as nitrate salt, which has, compared…”
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Spectroscopic investigation of the reaction mechanism of CopB-B, the catalytic fragment from an archaeal thermophilic ATP-driven heavy metal transporter by Völlmecke, Christian, Kötting, Carsten, Gerwert, Klaus, Lübben, Mathias

“…The mechanism of ATP hydrolysis of a shortened variant of the heavy metal-translocating P-type ATPase CopB of Sulfolobus solfataricus was studied. The…”
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Structural model of the CopA copper ATPase of Enterococcus hirae based on chemical cross-linking by Lübben, Mathias, Portmann, Reto, Kock, Gerd, Stoll, Raphael, Young, Malin M, Solioz, Marc

“…The CopA copper ATPase of Enterococcus hirae belongs to the family of heavy metal pumping CPx-type ATPases and shares 43% sequence similarity with the human…”
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