Search Results - "L'Etoile, Noelle D"
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Endogenous Nuclear RNAi Mediates Behavioral Adaptation to Odor
Published in Cell (29-08-2013)“…Most eukaryotic cells express small regulatory RNAs. The purpose of one class, the somatic endogenous siRNAs (endo-siRNAs), remains unclear. Here, we show that…”
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The cyclic nucleotide gated channel subunit CNG-1 instructs behavioral outputs in Caenorhabditis elegans by coincidence detection of nutritional status and olfactory input
Published in Neuroscience letters (06-10-2016)“…•The CNG channel subunit CNG-1 integrates odor and nutritional status.•CNG-1 is necessary for food-dependent olfactory choice behavior.•CNG-1 contributes to…”
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Changes in cGMP levels affect the localization of EGL-4 in AWC in Caenorhabditis elegans
Published in PloS one (03-02-2012)“…The Protein Kinase G, EGL-4, is required within the C. elegans AWC sensory neurons to promote olfactory adaptation. After prolonged stimulation of these…”
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Regulators of AWC-mediated olfactory plasticity in Caenorhabditis elegans
Published in PLoS genetics (01-12-2009)“…While most sensory neurons will adapt to prolonged stimulation by down-regulating their responsiveness to the signal, it is not clear which events initiate…”
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Chemosensory signal transduction in Caenorhabditis elegans
Published in Genetics (Austin) (31-03-2021)“…Abstract Chemosensory neurons translate perception of external chemical cues, including odorants, tastants, and pheromones, into information that drives…”
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Nuclear entry of a cGMP-dependent kinase converts transient into long-lasting olfactory adaptation
Published in Proceedings of the National Academy of Sciences - PNAS (30-03-2010)“…To navigate a complex and changing environment, an animal's sensory neurons must continually adapt to persistent cues while remaining responsive to novel…”
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The C. elegans cGMP-dependent protein kinase EGL-4 regulates nociceptive behavioral sensitivity
Published in PLoS genetics (01-07-2013)“…Signaling levels within sensory neurons must be tightly regulated to allow cells to integrate information from multiple signaling inputs and to respond to new…”
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Corrigendum to: Chemosensory signal transduction in Caenorhabditis elegans
Published in Genetics (Austin) (04-01-2022)Get full text
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Oncogene-regulated release of extracellular vesicles
Published in Developmental cell (12-07-2021)“…Oncogenes can alter metabolism by changing the balance between anabolic and catabolic processes. However, how oncogenes regulate tumor cell biomass remains…”
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Parallel encoding of sensory history and behavioral preference during Caenorhabditis elegans olfactory learning
Published in eLife (06-07-2016)“…Sensory experience modifies behavior through both associative and non-associative learning. In Caenorhabditis elegans, pairing odor with food deprivation…”
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See Elegans: Simple-to-use, accurate, and automatic 3D detection of neural activity from densely packed neurons
Published in PloS one (22-03-2024)“…In the emerging field of whole-brain imaging at single-cell resolution, which represents one of the new frontiers to investigate the link between brain…”
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C. elegans orthologs MUT-7/CeWRN-1 of Werner syndrome protein regulate neuronal plasticity
Published in eLife (01-03-2021)“…expresses human Werner syndrome protein (WRN) orthologs as two distinct proteins: MUT-7, with a 3'-5' exonuclease domain, and CeWRN-1, with helicase domains…”
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Eri1: a conserved enzyme at the crossroads of multiple RNA-processing pathways
Published in Trends in genetics (01-07-2014)“…Highlights • Eri1 processes ribosomal RNA, histone mRNA, and small regulatory RNAs. • Eri1 exemplifies a growing class of multifunctional small RNA-processing…”
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INX-18 and INX-19 play distinct roles in electrical synapses that modulate aversive behavior in Caenorhabditis elegans
Published in PLoS genetics (28-10-2019)“…In order to respond to changing environments and fluctuations in internal states, animals adjust their behavior through diverse neuromodulatory mechanisms. In…”
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Aversive Behavior in the Nematode C. elegans Is Modulated by cGMP and a Neuronal Gap Junction Network
Published in PLoS genetics (01-07-2016)“…All animals rely on their ability to sense and respond to their environment to survive. However, the suitability of a behavioral response is context-dependent,…”
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Contribution of the cyclic nucleotide gated channel subunit, CNG-3, to olfactory plasticity in Caenorhabditis elegans
Published in Scientific reports (13-03-2017)“…In Caenorhabditis elegans , the AWC neurons are thought to deploy a cGMP signaling cascade in the detection of and response to AWC sensed odors. Prolonged…”
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Olfaction and Odor Discrimination Are Mediated by the C. elegans Guanylyl Cyclase ODR-1
Published in Neuron (Cambridge, Mass.) (01-03-2000)“…Animals in complex environments must discriminate between salient and uninformative sensory cues. Caenorhabditis elegans uses one pair of olfactory neurons…”
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The Cyclic GMP-Dependent Protein Kinase EGL-4 Regulates Olfactory Adaptation in C. elegans
Published in Neuron (Cambridge, Mass.) (19-12-2002)“…Prolonged odor exposure causes a specific, reversible adaptation of olfactory responses. A genetic screen for negative regulators of olfaction uncovered…”
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CNP-1 (ARRD-17), a Novel Substrate of Calcineurin, Is Critical for Modulation of Egg-Laying and Locomotion in Response to Food and Lysine Sensation in Caenorhabditis elegans
Published in Journal of molecular biology (30-03-2012)“…Calcineurin is a Ca2+/calmodulin-dependent protein phosphatase involved in calcium signaling pathways. In Caenorhabditis elegans, the loss of calcineurin…”
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Polarized Dendritic Transport and the AP-1 μ1 Clathrin Adaptor UNC-101 Localize Odorant Receptors to Olfactory Cilia
Published in Neuron (Cambridge, Mass.) (01-08-2001)“…Odorant receptors and signaling proteins are localized to sensory cilia on olfactory dendrites. Using a GFP-tagged odorant receptor protein, Caenorhabditis…”
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