Search Results - "Kyung Hoon Lee"

Modulation of human transthyretin stability by the mutations at histidine 88 studied by free energy simulation by Lee, Kyung‐Hoon, Kuczera, Krzysztof

“…Human transthyretin (TTR) is a homotetrameric plasma protein associated with a high percentage of β‐sheet, which forms amyloid fibrils and accumulates in…”
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The nail matrix onychodermis - the curious reason behind the color of the lunula by Lee, Dongyoun, Lee, Taemin, Shim, Joonho, Park, Jihye, Lee, Kyung-Hoon

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Growing Living Composites with Ordered Microstructures and Exceptional Mechanical Properties by Xin, An, Su, Yipin, Feng, Shengwei, Yan, Minliang, Yu, Kunhao, Feng, Zhangzhengrong, Hoon Lee, Kyung, Sun, Lizhi, Wang, Qiming

“…Living creatures are continuous sources of inspiration for designing synthetic materials. However, living creatures are typically different from synthetic…”
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Crystallographic snapshots of sulfur insertion by lipoyl synthase by McLaughlin, Martin I., Lanz, Nicholas D., Goldman, Peter J., Lee, Kyung-Hoon, Booker, Squire J., Drennan, Catherine L.

“…Lipoyl synthase (LipA) catalyzes the insertion of two sulfur atoms at the unactivated C6 and C8 positions of a protein-bound octanoyl chain to produce the…”
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RlmN and AtsB as models for the overproduction and characterization of radical SAM proteins by Lanz, Nicholas D, Grove, Tyler L, Gogonea, Camelia Baleanu, Lee, Kyung-Hoon, Krebs, Carsten, Booker, Squire J

“…An explosion of remarkable chemical transformations has been witnessed in the past decade as a result of the radical S-adenosyl-l-methionine (SAM) (RS)…”
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Significant Therapeutic Effects of Adult Human Neural Stem Cells for Spinal Cord Injury Are Mediated by Monocyte Chemoattractant Protein-1 (MCP-1) by Kim, Chung Kwon, Won, Jeong-Seob, An, Jae Yeol, Lee, Ho Jin, Nam, Ah-Jin, Nam, Hyun, Lee, Ji Yeoun, Lee, Kyung-Hoon, Lee, Sun-Ho, Joo, Kyeung Min

“…The limited capability of regeneration in the human central nervous system leads to severe and permanent disabilities following spinal cord injury (SCI) while…”
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Single-Crystalline Mesoporous Molybdenum Nitride Nanowires with Improved Electrochemical Properties by Lee, Kyung-Hoon, Lee, Young-Woo, Ko, A-Ra, Cao, Guozhong, Park, Kyung-Won

“…We report single‐crystalline mesoporous molybdenum nitride nanowires (meso‐Mo3N2‐NWs) prepared by topotactic reaction using single‐crystalline molybdenum oxide…”
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Optimal Preclinical Conditions for Using Adult Human Multipotent Neural Cells in the Treatment of Spinal Cord Injury by Won, Jeong-Seob, Yeon, Je Young, Pyeon, Hee-Jang, Noh, Yu-Jeong, Hwang, Ji-Yoon, Kim, Chung Kwon, Nam, Hyun, Lee, Kyung-Hoon, Lee, Sun-Ho, Joo, Kyeung Min

“…Stem cell-based therapeutics are amongst the most promising next-generation therapeutic approaches for the treatment of spinal cord injury (SCI), as they may…”
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Neuroprotection by NGF and BDNF Against Neurotoxin-Exerted Apoptotic Death in Neural Stem Cells Are Mediated Through Trk Receptors, Activating PI3-Kinase and MAPK Pathways by Nguyen, Nga, Lee, Sang Bae, Lee, Yung Song, Lee, Kyung-Hoon, Ahn, Jee-Yin

“…Neural stem cells (NSC) undergo apoptotic cell death during development of nervous system and in adult. However, little is known about the biochemical…”
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Optimizing Contact Between Older Adults and Senior Services: South Korean users’ Perceptions of Gateway Institutions by Kim, Mi-ran, Lee, Kyung-Hoon

“…In response to the growing need for effective policy implementation strategies for older adults in South Korea, we propose the establishment of a user-centered…”
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알츠하이머병과 뇌소혈관질환의 연관성 by Kyung Hoon Lee, Koung Mi Kang

“…뇌소혈관질환은 뇌 자기공명영상에서 흔히 관찰되는 혈관성 변화로 뇌백질 고신호강도, 뇌미세출혈, 열공성 경색, 혈관주위공간 등을 포함한다. 이러한 혈관성 변화가 알츠하이머병(Alzheimer’s disease; 이하 AD)의 발병 및 진행과 관련되어 있고, 대표 병리인 베타 아밀로이드…”
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Akt attenuates apoptotic death through phosphorylation of H2A under hydrogen peroxide-induced oxidative stress in PC12 cells and hippocampal neurons by Park, Ji Hye, Kim, Chung Kwon, Lee, Sang Bae, Lee, Kyung-Hoon, Cho, Sung-Woo, Ahn, Jee-Yin

“…Although the essential role of protein kinase B (PKB)/Akt in cell survival signaling has been clearly established, the mechanism by which Akt mediates the…”
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Ribosomal Protein S3, a New Substrate of Akt, Serves as a Signal Mediator between Neuronal Apoptosis and DNA Repair[S] by Lee, Sang Bae, Kwon, Il-Sun, Park, Jihye, Lee, Kyung-Hoon, Ahn, Younghee, Lee, Cheolju, Kim, Joon, Choi, Soo Young, Cho, Sung-Woo, Ahn, Jee-Yin

“…RPS3, a conserved, eukaryotic ribosomal protein of the 40 S subunit, is required for ribosome biogenesis. Because ribosomal proteins are abundant and…”
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Pharmacological characterization of 4-hydroxy-N-desmethyl tamoxifen, a novel active metabolite of tamoxifen by JOHNSON, Michael D, HONG ZUO, LEE, Kyung-Hoon, TREBLEY, Joseph P, RAE, James Michael, WEATHERMAN, Ross V, DESTA, Zeruesanay, FLOCKHART, David A, SKAAR, Todd C

“…The antiestrogen tamoxifen is extensively metabolized in patients to form a series of compounds with altered affinity for estrogen receptors (ERs), the primary…”
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Development of a risk assessment model against disasters in high-rise buildings and results of a building simulation analysis by Kim, Tae-Young, Han, Gi-Sung, Kang, Boo-Sung, Lee, Kyung-Hoon

“…This study developed a method to assess a building's risk against disaster, tentatively named the Korean Integrated Disaster Evaluation Simulator (K-IDES)…”
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The presence and localization of onychodermis (specialized nail mesenchyme) containing onychofibroblasts in the nail unit: a morphological and immunohistochemical study by Lee, Dong-Youn, Park, Ji-Hye, Shin, Hyun-Tae, Yang, Jun-Mo, Jang, Kee-Taek, Kwon, Ghee Young, Lee, Kyung-Hoon, Shim, Jong Sup

“…Lee D‐Y, Park J‐H, Shin H‐T, Yang J‐M, Jang K‐T, Kwon G Y, Lee K‐H & Shim J S 
(2012) Histopathology 61, 123–130 The presence and localization of onychodermis…”
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Characterization of RimO, a New Member of the Methylthiotransferase Subclass of the Radical SAM Superfamily by Lee, Kyung-Hoon, Saleh, Lana, Anton, Brian P, Madinger, Catherine L, Benner, Jack S, Iwig, David F, Roberts, Richard J, Krebs, Carsten, Booker, Squire J

“…RimO, encoded by the yliG gene in Escherichia coli, has been recently identified in vivo as the enzyme responsible for the attachment of a methylthio group on…”
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Akt1-Inhibitor of DNA binding2 is essential for growth cone formation and axon growth and promotes central nervous system axon regeneration by Ko, Hyo Rim, Kwon, Il-Sun, Hwang, Inwoo, Jin, Eun-Ju, Shin, Joo-Ho, Brennan-Minnella, Angela M, Swanson, Raymond, Cho, Sung-Woo, Lee, Kyung-Hoon, Ahn, Jee-Yin

“…Mechanistic studies of axon growth during development are beneficial to the search for neuron-intrinsic regulators of axon regeneration. Here, we discovered…”
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CD13 is a marker for onychofibroblasts within nail matrix onychodermis: Comparison of its expression patterns in the nail unit and in the hair follicle by Park, Ji‐Hye, Lee, Dong‐Youn, Jang, Kee‐Taek, Ha, Sang‐Yun, Kwon, Ghee Young, Lee, Kyung‐Hoon, Shim, Jong Sup, Kwon, Eun Ji

“…Background We previously demonstrated the presence of onychodermis, a specialized mesenchymal cell population beneath the nail matrix and proximal nail bed…”
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알츠하이머병과 뇌소혈관질환의 연관성 by 이경훈, 강경미, Kyung Hoon Lee, Koung Mi Kang

“…Cerebral small vessel disease (CSVD) includes vascular lesions detected on brain MRI, such as white matter hyperintensities, lacunar infarctions, microbleeds,…”
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