Search Results - "Kyu Sang Song"

Identification of a molecular signature of prognostic subtypes in diffuse-type gastric cancer by Kim, Seon-Kyu, Kim, Hee-Jin, Park, Jong-Lyul, Heo, Haejeong, Kim, Seon-Young, Lee, Sang-Il, Song, Kyu-Sang, Kim, Woo-Ho, Kim, Yong Sung

“…Background Although recent advances in high-throughput technology have provided many insights into gastric cancer (GC), few reliable biomarkers for…”
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ONECUT2 upregulation is associated with CpG hypomethylation at promoter‐proximal DNA in gastric cancer and triggers ACSL5 by Seo, Eun‐Hye, Kim, Hee‐Jin, Kim, Jong‐Hwan, Lim, Byungho, Park, Jong‐Lyul, Kim, Seon‐Young, Lee, Sang‐Il, Jeong, Hyun‐Yong, Song, Kyu‐Sang, Kim, Yong‐Sung

“…Many studies have focused on global hypomethylation or hypermethylation of tumor suppressor genes, but less is known about the impact of promoter…”
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HOXC10 overexpression promotes cell proliferation and migration in gastric cancer by Kim, Jina, Bae, Dong-Hyuck, Kim, Jong Hwan, Song, Kyu-Sang, Kim, Yong Sung, Kim, Seon-Young

“…Homeodomain‑containing gene 10 (HOXC10) is a member of the homeobox transcription factors that plays an important role in the development of multicellular…”
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Integrative genomics analysis reveals the multilevel dysregulation and oncogenic characteristics of TEAD4 in gastric cancer by Lim, Byungho, Park, Jong-Lyul, Kim, Hee-Jin, Park, Young-Kyu, Kim, Jeong-Hwan, Sohn, Hyun Ahm, Noh, Seung-Moo, Song, Kyu-Sang, Kim, Woo-Ho, Kim, Yong Sung, Kim, Seon-Young

“…Tumorigenesis is a consequence of failures of multistep defense mechanisms against deleterious perturbations that occur at the genomic, epigenomic,…”
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Whole genome MBD-seq and RRBS analyses reveal that hypermethylation of gastrointestinal hormone receptors is associated with gastric carcinogenesis by Kim, Hee-Jin, Kang, Tae-Wook, Haam, Keeok, Kim, Mirang, Kim, Seon-Kyu, Kim, Seon-Young, Lee, Sang-Il, Song, Kyu-Sang, Jeong, Hyun-Yong, Kim, Yong Sung

“…DNA methylation is a regulatory mechanism in epigenetics that is frequently altered during human carcinogenesis. To detect critical methylation events…”
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Gastric Cancer and the Daily Intake of the Major Dish Groups Contributing to Sodium Intake: A Case-Control Study in Korea by Kwak, Jung-Hyun, Eun, Chang-Soo, Han, Dong-Soo, Kim, Yong-Sung, Song, Kyu-Sang, Choi, Bo-Youl, Kim, Hyun-Ja

“…Studies on the association between gastric cancer (GC) and the intake of soup-based dish groups (noodles and dumplings, soups, and stews), which are…”
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Risk factors for metachronous gastric carcinoma development after endoscopic resection of gastric dysplasia: Retrospective, single-center study by Hee Seok Moon Gee Young Yun Ju Seok Kim Hyuk Soo Eun Sun Hyung Kang Jae Kyu Sung Hyun Yong JeongDepartment of Internal Medicine, Chungnam National University Hospital, Chungnam National University School of Medicine Kyu-Sang Song

“…AIM To determine the gastric adenocarcinoma(GAC)occurrence rate and related factors,we evaluated the follow-up results of patients confirmed to have gastric…”
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Aberrant upregulation of ASCL2 by promoter demethylation promotes the growth and resistance to 5‐fluorouracil of gastric cancer cells by Kwon, Oh‐Hyung, Park, Jong‐Lyul, Baek, Su‐Jin, Noh, Seung‐Moo, Song, Kyu‐Sang, Kim, Seon‐Young, Kim, Yong Sung

“…Achaete scute‐like 2 (ASCL2), a basic helix‐loop‐helix transcription factor, plays an essential role in the maintenance of adult intestinal stem cells…”
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Regulation of glycogen synthase kinase-3 by thymosin beta-4 is associated with gastric cancer cell migration by Ryu, Yun-Kyoung, Lee, Yu-Sun, Lee, Geun-Hee, Song, Kyu-Sang, Kim, Yong-Sung, Moon, Eun-Yi

“…Thymosin beta‐4 (Tβ4), actin‐sequestering protein, plays important roles in many cellular functions including cancer cell migrations. Glycogen synthase kinase…”
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Association between soy products, fruits, vegetables, and dairy products and gastric cancer risk in Helicobacter pylori-infected subjects: a case-control study in Korea by Kwak, Jung Hyun, Eun, Chang Soo, Han, Dong Soo, Kim, Yong Sung, Song, Kyu Sang, Choi, Bo Youl, Kim, Hyun Ja

“…Consumption of certain protective foods may help inhibit ( ) associated gastric pathologies. However, studies conducted to assess the efficacy of protective…”
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Pyruvate kinase M2 promotes the growth of gastric cancer cells via regulation of Bcl-xL expression at transcriptional level by Kwon, Oh-Hyung, Kang, Tae-Wook, Kim, Jeong-Hwan, Kim, Mirang, Noh, Seung-Moo, Song, Kyu-Sang, Yoo, Hyang-Sook, Kim, Woo-Ho, Xie, Zhi, Pocalyko, David, Kim, Seon-Young, Kim, Yong Sung

“…► PKM2 is associated with poor survival of gastric cancer patients. ► PKM2 affects cell survival by regulating Bcl-xL at the transcriptional level. ► PKM2…”
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Epigenetic regulation of microRNA-10b and targeting of oncogenic MAPRE1 in gastric cancer by Kim, Kwoneel, Lee, Han-Chul, Park, Jong-Lyul, Kim, Mirang, Kim, Seon-Young, Noh, Seung-Moo, Song, Kyu-Sang, Kim, Jin Cheon, Kim, Yong Sung

“…MicroRNAs act as negative regulators of gene expression, and the altered expression of microRNAs by epigenetic mechanisms is strongly implicated in…”
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Clinical Manifestations and Genotype of Primary Ciliary Dyskinesia Diagnosed in Korea: Multicenter Study by Kim, Minji, Lee, Mi-Hee, Hong, Soo-Jong, Yu, Jinho, Cho, Joongbum, Suh, Dong In, Kim, Hyung Young, Kim, Hye-Young, Jung, Sungsu, Lee, Eun, Lee, Sooyoung, Jeong, Kyunguk, Shim, Jung Yeon, Kim, Jeong Hee, Chung, Hai Lee, Jang, Yoon Young, Kwon, Ji-Won, Seo, Ju-Hee, Kim, Ju Hee, Ahn, Ji Young, Song, Kun-Baek, Song, Kyu-Sang, Kim, So Yeon, Kim, Seon Young, Kil, Hong Ryang, Chung, Eun Hee

“…Purpose Primary ciliary dyskinesia (PCD) is a genetically heterogeneous disorder that leads to secondary ciliary dysfunction. PCD is a rare disease, and data…”
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Aberrant Methylation of Somatostatin Receptor 2 Gene Is Initiated in Aged Gastric Mucosa Infected with Helicobacter pylori and Consequential Gene Silencing Is Associated with Establishment of Inflammatory Microenvironment In Vitro Study by Kim, Hee-Jin, Park, Jong-Lyul, Yoon, Byoung-Ha, Haam, Keeok, Heo, Haejeong, Kim, Jong-Hwan, Kim, Seon-Young, Kim, Mirang, Kim, Woo-Ho, Lee, Sang-Il, Song, Kyu-Sang, Ahn, Kwang-Sung, Kim, Yong Sung

“…The loss-of-function variants are thought to be associated with inflammation in the stomach. We here aimed to evaluate the extent and role of methylation at…”
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Epigenetic silencing of miR‐1271 enhances MEK1 and TEAD4 expression in gastric cancer by Lim, Byungho, Kim, Hee‐Jin, Heo, Haejeong, Huh, Nanhyung, Baek, Su‐Jin, Kim, Jong‐Hwan, Bae, Dong‐Hyuck, Seo, Eun‐Hye, Lee, Sang‐Il, Song, Kyu‐Sang, Kim, Seon‐Young, Kim, Yong Sung, Kim, Mirang

“…Epigenetic dysregulation is a major driver of tumorigenesis. To identify tumor‐suppressive microRNAs repressed by DNA methylation in gastric cancer (GC), we…”
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LINE-1 hypomethylation is inversely correlated with UHRF1 overexpression in gastric cancer by Hong, Jang Hee, Jin, Eun-Heui, Kim, Soyeon, Song, Kyu-Sang, Sung, Jae Kyu

“…DNA methylation is an important epigenetic modification that alters gene expression; DNA hypomethylation contributes to tumorigenesis through multiple…”
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Aberrant up-regulation of LAMB3 and LAMC2 by promoter demethylation in gastric cancer by Kwon, Oh-Hyung, Park, Jong-Lyul, Kim, Mirang, Kim, Jeong-Hwan, Lee, Han-Chul, Kim, Hee-Jin, Noh, Seung-Moo, Song, Kyu-Sang, Yoo, Hyang-Sook, Paik, Sang-Gi, Kim, Seon-Young, Kim, Yong Sung

“…► Higher expression levels of LAMB3 and LAMC2 mRNA in tumor tissues than in normal tissues. ► DNA hypomethylation was associated with the up-regulation of both…”
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Epigenetic silencing of BTB and CNC homology 2 and concerted promoter CpG methylation in gastric cancer by Haam, Keeok, Kim, Hee-Jin, Lee, Kyung-Tae, Kim, Jeong-Hwan, Kim, Mirang, Kim, Seon-Young, Noh, Seung-Moo, Song, Kyu-Sang, Kim, Yong Sung

“…Highlights • We found a Not I site methylated on BACH2 promoter in gastric tumors. • The methylation was significantly associated with decreased gene…”
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Preoperative chemoradiation using oral capecitabine in locally advanced rectal cancer by Kim, Jun-Sang, Kim, Jae-Sung, Cho, Moon-June, Song, Kyu-Sang, Yoon, Wan-Hee

“…Capecitabine (Xeloda) is a new orally administered fluoropyrimidine carbamate that was rationally designed to exert its effect by tumor-selective activation…”
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Association between soy products, fruits, vegetables, and dairy products and gastric cancer risk in Helicobacter pylori-infected subjects: a case-control study in Korea by Jung Hyun Kwak, Chang Soo Eun, Dong Soo Han, Yong Sung Kim, Kyu Sang Song, Bo Youl Choi, Hyun Ja Kim

“…BACKGROUND/OBJECTIVES: Consumption of certain protective foods may help inhibit Helicobacter pylori (H. pylori) associated gastric pathologies. However,…”
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