Search Results - "Kyte, S Lauren"

Effects of paclitaxel on the development of neuropathy and affective behaviors in the mouse by Toma, Wisam, Kyte, S. Lauren, Bagdas, Deniz, Alkhlaif, Yasmin, Alsharari, Shakir D., Lichtman, Aron H., Chen, Zhi-Jian, Del Fabbro, Egidio, Bigbee, John W., Gewirtz, David A., Damaj, M. Imad

“…Paclitaxel, one of the most commonly used cancer chemotherapeutic drugs, effectively extends the progression-free survival of breast, lung, and ovarian cancer…”
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Monoacylglycerol Lipase Inhibitors Reverse Paclitaxel-Induced Nociceptive Behavior and Proinflammatory Markers in a Mouse Model of Chemotherapy-Induced Neuropathy by Curry, Zachary A, Wilkerson, Jenny L, Bagdas, Deniz, Kyte, S Lauren, Patel, Nipa, Donvito, Giulia, Mustafa, Mohammed A, Poklis, Justin L, Niphakis, Micah J, Hsu, Ku-Lung, Cravatt, Benjamin F, Gewirtz, David A, Damaj, M Imad, Lichtman, Aron H

“…Although paclitaxel effectively treats various cancers, its debilitating peripheral neuropathic pain side effects often persist long after treatment has ended…”
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The α7 nicotinic receptor silent agonist R-47 prevents and reverses paclitaxel-induced peripheral neuropathy in mice without tolerance or altering nicotine reward and withdrawal by Toma, Wisam, Kyte, S. Lauren, Bagdas, Deniz, Jackson, Asti, Meade, Julie A., Rahman, Faria, Chen, Zhi-Jian, Del Fabbro, Egidio, Cantwell, Lucas, Kulkarni, Abhijit, Thakur, Ganesh A., Papke, Roger L., Bigbee, John W., Gewirtz, David A., Damaj, M.Imad

“…Various antitumor drugs, including paclitaxel, frequently cause chemotherapy-induced peripheral neuropathy (CIPN) that can be sustained even after therapy has…”
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Nicotine Prevents and Reverses Paclitaxel-Induced Mechanical Allodynia in a Mouse Model of CIPN by Kyte, S Lauren, Toma, Wisam, Bagdas, Deniz, Meade, Julie A, Schurman, Lesley D, Lichtman, Aron H, Chen, Zhi-Jian, Del Fabbro, Egidio, Fang, Xianjun, Bigbee, John W, Damaj, M Imad, Gewirtz, David A

“…Chemotherapy-induced peripheral neuropathy (CIPN), a consequence of peripheral nerve fiber dysfunction or degeneration, continues to be a dose-limiting and…”
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Abstract 602: The α7 nicotinic acetylcholine receptor silent agonist R-47 prevents and reverses paclitaxel-induced peripheral neuropathy without enhancing the proliferation of lung cancer cells or interfering with paclitaxel-induced antitumor activity by Kyte, S Lauren, Toma, Wisam, Thakur, Ganeshsingh, Damaj, M Imad, Gewirtz, David A.

“…Abstract While cancer chemotherapy continues to significantly contribute to the number of cancer survivors, exposure to these drugs can often result in…”
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Abstract 986: Targeting nicotinic acetylcholine receptors for the prevention and reversal of chemotherapy-induced peripheral neuropathy by Kyte, S Lauren, Toma, Wisam, Thakur, Ganeshsingh, Damaj, M Imad, Gewirtz, David A.

“…Abstract While chemotherapy has played a significant role in the survival of cancer patients, exposure to drugs such as the taxanes, platinum-based compounds,…”
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Abstract 5470: Reversibility of therapy-induced senescence in non-small cell lung cancer as a model of cancer recurrence by Saleh, Tareq, Cudjoe, Emmanuel K., Kyte, S Lauren, Henderson, Scott C., Elmore, Lynne W., Gewirtz, David A.

“…Abstract Disease recurrence at either primary or metastatic tumor sites arising from dormant tumors is largely responsible for the morbidity and mortality of…”
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