Search Results - "Kyrou, Kyros"

A male-biased sex-distorter gene drive for the human malaria vector Anopheles gambiae by Simoni, Alekos, Hammond, Andrew M., Beaghton, Andrea K., Galizi, Roberto, Taxiarchi, Chrysanthi, Kyrou, Kyros, Meacci, Dario, Gribble, Matthew, Morselli, Giulia, Burt, Austin, Nolan, Tony, Crisanti, Andrea

“…Only female insects transmit diseases such as malaria, dengue and Zika; therefore, control methods that bias the sex ratio of insect offspring have long been…”
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Gene-drive suppression of mosquito populations in large cages as a bridge between lab and field by Hammond, Andrew, Pollegioni, Paola, Persampieri, Tania, North, Ace, Minuz, Roxana, Trusso, Alessandro, Bucci, Alessandro, Kyrou, Kyros, Morianou, Ioanna, Simoni, Alekos, Nolan, Tony, Müller, Ruth, Crisanti, Andrea

“…CRISPR-based gene-drives targeting the gene doublesex in the malaria vector Anopheles gambiae effectively suppressed the reproductive capability of mosquito…”
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A genetically encoded anti-CRISPR protein constrains gene drive spread and prevents population suppression by Taxiarchi, Chrysanthi, Beaghton, Andrea, Don, Nayomi Illansinhage, Kyrou, Kyros, Gribble, Matthew, Shittu, Dammy, Collins, Scott P., Beisel, Chase L., Galizi, Roberto, Crisanti, Andrea

“…CRISPR-based gene drives offer promising means to reduce the burden of pests and vector-borne diseases. These techniques consist of releasing genetically…”
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The creation and selection of mutations resistant to a gene drive over multiple generations in the malaria mosquito by Hammond, Andrew M, Kyrou, Kyros, Bruttini, Marco, North, Ace, Galizi, Roberto, Karlsson, Xenia, Kranjc, Nace, Carpi, Francesco M, D'Aurizio, Romina, Crisanti, Andrea, Nolan, Tony

“…Gene drives have enormous potential for the control of insect populations of medical and agricultural relevance. By preferentially biasing their own…”
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Regulating the expression of gene drives is key to increasing their invasive potential and the mitigation of resistance by Hammond, Andrew, Karlsson, Xenia, Morianou, Ioanna, Kyrou, Kyros, Beaghton, Andrea, Gribble, Matthew, Kranjc, Nace, Galizi, Roberto, Burt, Austin, Crisanti, Andrea, Nolan, Tony

“…Homing-based gene drives use a germline source of nuclease to copy themselves at specific target sites in a genome and bias their inheritance. Such gene drives…”
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A CRISPR-Cas9 sex-ratio distortion system for genetic control by Galizi, Roberto, Hammond, Andrew, Kyrou, Kyros, Taxiarchi, Chrysanthi, Bernardini, Federica, O’Loughlin, Samantha M., Papathanos, Philippos-Aris, Nolan, Tony, Windbichler, Nikolai, Crisanti, Andrea

“…Genetic control aims to reduce the ability of insect pest populations to cause harm via the release of modified insects. One strategy is to bias the…”
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Assessing the acoustic behaviour of Anopheles gambiae (s.l.) dsxF mutants: implications for vector control by Su, Matthew P, Georgiades, Marcos, Bagi, Judit, Kyrou, Kyros, Crisanti, Andrea, Albert, Joerg T

“…Abstract Background Release of gene-drive mutants to suppress Anopheles mosquito reproduction is a promising method of malaria control. However, many…”
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Author Correction: A male-biased sex-distorter gene drive for the human malaria vector Anopheles gambiae by Simoni, Alekos, Hammond, Andrew M., Beaghton, Andrea K., Galizi, Roberto, Taxiarchi, Chrysanthi, Kyrou, Kyros, Meacci, Dario, Gribble, Matthew, Morselli, Giulia, Burt, Austin, Nolan, Tony, Crisanti, Andrea

“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
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Single-cell profiling of Anopheles gambiae spermatogenesis defines the onset of meiotic silencing and premeiotic overexpression of the X chromosome by Page, Nicole, Taxiarchi, Chrysanthi, Tonge, Daniel, Kuburic, Jasmina, Chesters, Emily, Kriezis, Antonios, Kyrou, Kyros, Game, Laurence, Nolan, Tony, Galizi, Roberto

“…Understanding development and genetic regulation in the Anopheles gambiae germline is essential to engineer effective genetic control strategies targeting this…”
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A CRISPR–Cas9 gene drive targeting doublesex causes complete population suppression in caged Anopheles gambiae mosquitoes by Kyrou, Kyros, Hammond, Andrew M, Galizi, Roberto, Kranjc, Nace, Burt, Austin, Beaghton, Andrea K, Nolan, Tony, Crisanti, Andrea

“…Complete population collapse of malaria vector Anopheles gambiae in cages is achieved using a gene drive that targets doublesex . In the human malaria vector…”
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High-resolution transcriptional profiling of Anopheles gambiae spermatogenesis reveals mechanisms of sex chromosome regulation by Taxiarchi, Chrysanthi, Kranjc, Nace, Kriezis, Antonios, Kyrou, Kyros, Bernardini, Federica, Russell, Steven, Nolan, Tony, Crisanti, Andrea, Galizi, Roberto

“…Although of high priority for the development of genetic tools to control malaria-transmitting mosquitoes, only a few germline-specific regulatory regions have…”
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A CRISPR-Cas9 gene drive system targeting female reproduction in the malaria mosquito vector Anopheles gambiae by Hammond, Andrew, Galizi, Roberto, Kyrou, Kyros, Simoni, Alekos, Siniscalchi, Carla, Katsanos, Dimitris, Gribble, Matthew, Baker, Dean, Marois, Eric, Russell, Steven, Burt, Austin, Windbichler, Nikolai, Crisanti, Andrea, Nolan, Tony

“…Development of a CRISPR/Cas9-based gene drive system in Anopheles gambiae , the main vector for the malaria parasite, paves the way for control of this pest…”
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Natural Infection of C. elegans by an Oomycete Reveals a New Pathogen-Specific Immune Response by Osman, Guled A., Fasseas, Michael K., Koneru, Sneha L., Essmann, Clara L., Kyrou, Kyros, Srinivasan, Mandayam A., Zhang, Gaotian, Sarkies, Peter, Félix, Marie-Anne, Barkoulas, Michalis

“…In its natural habitat, the nematode Caenorhabditis elegans encounters a plethora of other organisms, including many that are pathogenic [1, 2]. The study of…”
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Cross-Species Y Chromosome Function Between Malaria Vectors of the Anopheles gambiae Species Complex by Bernardini, Federica, Galizi, Roberto, Wunderlich, Mariana, Taxiarchi, Chrysanthi, Kranjc, Nace, Kyrou, Kyros, Hammond, Andrew, Nolan, Tony, Lawniczak, Mara N K, Papathanos, Philippos Aris, Crisanti, Andrea, Windbichler, Nikolai

“…Y chromosome function, structure and evolution is poorly understood in many species, including the genus of mosquitoes-an emerging model system for studying…”
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