Search Results - "Kyriakis, Dimitrios"

Multi-omics integration of scRNA-seq time series data predicts new intervention points for Parkinson’s disease by Mihajlović, Katarina, Ceddia, Gaia, Malod-Dognin, Noël, Novak, Gabriela, Kyriakis, Dimitrios, Skupin, Alexander, Pržulj, Nataša

“…Parkinson’s disease (PD) is a complex neurodegenerative disorder without a cure. The onset of PD symptoms corresponds to 50% loss of midbrain dopaminergic…”
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Single-Cell Transcriptomics and In Situ Morphological Analyses Reveal Microglia Heterogeneity Across the Nigrostriatal Pathway by Uriarte Huarte, Oihane, Kyriakis, Dimitrios, Heurtaux, Tony, Pires-Afonso, Yolanda, Grzyb, Kamil, Halder, Rashi, Buttini, Manuel, Skupin, Alexander, Mittelbronn, Michel, Michelucci, Alessandro

“…Microglia are the resident immune effector cells of the central nervous system (CNS) rapidly reacting to various pathological stimuli to maintain CNS…”
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Early-to-mid stage idiopathic Parkinson’s disease shows enhanced cytotoxicity and differentiation in CD8 T-cells in females by Capelle, Christophe M., Ciré, Séverine, Hedin, Fanny, Hansen, Maxime, Pavelka, Lukas, Grzyb, Kamil, Kyriakis, Dimitrios, Hunewald, Oliver, Konstantinou, Maria, Revets, Dominique, Tslaf, Vera, Marques, Tainá M., Gomes, Clarissa P. C., Baron, Alexandre, Domingues, Olivia, Gomez, Mario, Zeng, Ni, Betsou, Fay, May, Patrick, Skupin, Alexander, Cosma, Antonio, Balling, Rudi, Krüger, Rejko, Ollert, Markus, Hefeng, Feng Q.

“…Neuroinflammation in the brain contributes to the pathogenesis of Parkinson’s disease (PD), but the potential dysregulation of peripheral immunity has not been…”
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Single-cell transcriptomics of human iPSC differentiation dynamics reveal a core molecular network of Parkinson’s disease by Novak, Gabriela, Kyriakis, Dimitrios, Grzyb, Kamil, Bernini, Michela, Rodius, Sophie, Dittmar, Gunnar, Finkbeiner, Steven, Skupin, Alexander

“…Parkinson’s disease (PD) is the second-most prevalent neurodegenerative disorder, characterized by the loss of dopaminergic neurons (mDA) in the midbrain. The…”
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Glioblastoma-instructed microglia transition to heterogeneous phenotypic states with phagocytic and dendritic cell-like features in patient tumors and patient-derived orthotopic xenografts by Yabo, Yahaya A, Moreno-Sanchez, Pilar M, Pires-Afonso, Yolanda, Kaoma, Tony, Nosirov, Bakhtiyor, Scafidi, Andrea, Ermini, Luca, Lipsa, Anuja, Oudin, Anaïs, Kyriakis, Dimitrios, Grzyb, Kamil, Poovathingal, Suresh K, Poli, Aurélie, Muller, Arnaud, Toth, Reka, Klink, Barbara, Berchem, Guy, Berthold, Christophe, Hertel, Frank, Mittelbronn, Michel, Heiland, Dieter H, Skupin, Alexander, Nazarov, Petr V, Niclou, Simone P, Michelucci, Alessandro, Golebiewska, Anna

“…A major contributing factor to glioblastoma (GBM) development and progression is its ability to evade the immune system by creating an immune-suppressive…”
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Assessing Genetic Variation in Wild and Domesticated Pikeperch Populations: Implications for Conservation and Fish Farming by Tsaparis, Dimitrios, Lecocq, Thomas, Kyriakis, Dimitrios, Oikonomaki, Katerina, Fontaine, Pascal, Tsigenopoulos, Costas S

“…The pikeperch is a freshwater/brackish water fish species with growing interest for European aquaculture. Wild populations show signs of decline in many areas…”
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Scanning of Genetic Variants and Genetic Mapping of Phenotypic Traits in Gilthead Sea Bream Through ddRAD Sequencing by Kyriakis, Dimitrios, Kanterakis, Alexandros, Manousaki, Tereza, Tsakogiannis, Alexandros, Tsagris, Michalis, Tsamardinos, Ioannis, Papaharisis, Leonidas, Chatziplis, Dimitris, Potamias, George, Tsigenopoulos, Costas S

“…Gilthead sea bream (Sparus aurata) is a teleost of considerable economic importance in Southern European aquaculture. The aquaculture industry shows a growing…”
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In Vivo Effects of Lipopolysaccharide on Peroxisome Proliferator-Activated Receptor Expression in Juvenile Gilthead Seabream (Sparus Aurata) by Antonopoulou, Efthimia, Kaitetzidou, Elisavet, Castellana, Barbara, Panteli, Nikolas, Kyriakis, Dimitrios, Vraskou, Yoryia, Planas, Josep V

“…Fish are constantly exposed to microorganisms in the aquatic environment, many of which are bacterial pathogens. Bacterial pathogens activate the innate immune…”
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Rac1 and Rac3 GTPases and TPC2 are required for axonal outgrowth and migration of cortical interneurons by Kounoupa, Zouzana, Tivodar, Simona, Theodorakis, Kostas, Kyriakis, Dimitrios, Denaxa, Myrto, Karagogeos, Domna

“…Rho GTPases, among them Rac1 and Rac3, are major transducers of extracellular signals and are involved in multiple cellular processes. In cortical…”
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CyTOF and Flow Cytometry dataset assocaited with "Early-to-mid stage idiopathic Parkinson's disease shows enhanced cytotoxicity and differentiation in CD8 T-cells in females" by Capelle, Christophe M., Ciré, Séverine, Hedin, Fanny, Hansen, Maxime, Pavelka, Lukas, Grzyb, Kamil, Kyriakis, Dimitrios, Hunewald, Oliver, Konstantinou, Maria, Revets, Dominique, Tslaf, Vera, Marques, Tainá M., Gomes, Clarissa P. C., Baron, Alexandre, Domingues, Olivia, Gomez, Mario, Zeng, Ni, Betsou, Fay, May, Patrick, Skupin, Alexander, Cosma, Antonio, Balling, Rudi, Krüger, Rejko, Ollert, Markus, Hefeng, Feng Q.

“…This dataset contains all the raw mass cytometry (CyTOF) and flow cytometry fcs files associated with Capelle et al. 'Early-to-mid stage idiopathic Parkinson's…”
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