Search Results - "Kyparissoudis, Konstantinos"

Diverse cytokine production by NKT cell subsets and identification of an IL-17-producing CD4⁻NK1.1⁻ NKT cell population by Coquet, Jonathan M, Chakravarti, Sumone, Kyparissoudis, Konstantinos, McNab, Finlay W, Pitt, Lauren A, McKenzie, Brent S, Berzins, Stuart P, Smyth, Mark J, Godfrey, Dale I

“…NKT cell subsets can be divided based on CD4 and NK1.1 expression and tissue of origin, but the developmental and functional relationships between the…”
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IL-21 Is Produced by NKT Cells and Modulates NKT Cell Activation and Cytokine Production by Coquet, Jonathan M, Kyparissoudis, Konstantinos, Pellicci, Daniel G, Besra, Gurdyal, Berzins, Stuart P, Smyth, Mark J, Godfrey, Dale I

“…The common gamma-chain cytokine, IL-21, is produced by CD4(+) T cells and mediates potent effects on a variety of immune cells including NK, T, and B cells…”
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Differential antitumor immunity mediated by NKT cell subsets in vivo by Crowe, Nadine Y, Coquet, Jonathan M, Berzins, Stuart P, Kyparissoudis, Konstantinos, Keating, Rachael, Pellicci, Daniel G, Hayakawa, Yoshihiro, Godfrey, Dale I, Smyth, Mark J

“…We showed previously that NKT cell-deficient TCR Jalpha18(-/-) mice are more susceptible to methylcholanthrene (MCA)-induced sarcomas, and that normal tumor…”
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ZBTB7B (Th-POK) regulates the development of IL-17-producing CD1d-restricted mouse NKT cells by Enders, Anselm, Stankovic, Sanda, Teh, Charis, Uldrich, Adam P, Yabas, Mehmet, Juelich, Torsten, Altin, John A, Frankenreiter, Sandra, Bergmann, Hannes, Roots, Carla M, Kyparissoudis, Konstantinos, Goodnow, Chris C, Godfrey, Dale I

“…CD1d-dependent NKT cells represent a heterogeneous family of effector T cells including CD4(+)CD8(-) and CD4(-)CD8(-) subsets that respond to glycolipid Ags…”
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Strain-dependent differences in bone development, myeloid hyperplasia, morbidity and mortality in ptpn2-deficient mice by Wiede, Florian, Chew, Sock Hui, van Vliet, Catherine, Poulton, Ingrid J, Kyparissoudis, Konstantinos, Sasmono, Tedjo, Loh, Kim, Tremblay, Michel L, Godfrey, Dale I, Sims, Natalie A, Tiganis, Tony

“…Single nucleotide polymorphisms in the gene encoding the protein tyrosine phosphatase TCPTP (encoded by PTPN2) have been linked with the development of…”
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Peripheral NKT Cells in Simian Immunodeficiency Virus-Infected Macaques by FERNANDEZ, Caroline S, CHAN, Angela C, KYPARISSOUDIS, Konstantinos, DE ROSE, Robert, GODFREY, Dale I, KENT, Stephen J

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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T cell protein tyrosine phosphatase attenuates T cell signaling to maintain tolerance in mice by Wiede, Florian, Shields, Benjamin J, Kyparissoudis, Sock Hui Chew Konstantinos, van Vliet, Catherine, Galic, Sandra, Tremblay, Michel L, Russell, Sarah M, Godfrey, Dale I, Tiganis, Tony

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T cell protein tyrosine phosphatase attenuates T cell signaling to maintain tolerance in mice by Wiede, Florian, Shields, Benjamin J, Chew, Sock Hui, Kyparissoudis, Konstantinos, van Vliet, Catherine, Galic, Sandra, Tremblay, Michel L, Russell, Sarah M, Godfrey, Dale I, Tiganis, Tony

“…Many autoimmune diseases exhibit familial aggregation, indicating that they have genetic determinants. Single nucleotide polymorphisms in PTPN2, which encodes…”
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Correction: DX5/CD49b-Positive T Cells Are Not Synonymous with CD1d-Dependent NKT Cells by Pellicci, Daniel G, Hammond, Kirsten J L, Coquet, Jonathan, Kyparissoudis, Konstantinos, Brooks, Andrew G, Kedzierska, Katherine, Keating, Rachael, Turner, Stephen, Berzins, Stuart, Smyth, Mark J, Godfrey, Dale I

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Differential Recognition of CD1d-α-Galactosyl Ceramide by the Vβ8.2 and Vβ7 Semi-invariant NKT T Cell Receptors by Pellicci, Daniel G., Patel, Onisha, Kjer-Nielsen, Lars, Pang, Siew Siew, Sullivan, Lucy C., Kyparissoudis, Konstantinos, Brooks, Andrew G., Reid, Hugh H., Gras, Stephanie, Lucet, Isabelle S., Koh, Ruide, Smyth, Mark J., Mallevaey, Thierry, Matsuda, Jennifer L., Gapin, Laurent, McCluskey, James, Godfrey, Dale I., Rossjohn, Jamie

“…The semi-invariant natural killer T cell receptor (NKT TCR) recognizes CD1d-lipid antigens. Although the TCRα chain is typically invariant, the β chain…”
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CD4+CD25+ T Regulatory Cells Suppress NK Cell-Mediated Immunotherapy of Cancer by Smyth, Mark J, Teng, Michele W. L, Swann, Jeremy, Kyparissoudis, Konstantinos, Godfrey, Dale I, Hayakawa, Yoshihiro

“…CD4+CD25+ regulatory T cells (Treg) that suppress T cell-mediated immune responses may also regulate other arms of an effective immune response. In particular,…”
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A semi-invariant Vα10+ T cell antigen receptor defines a population of natural killer T cells with distinct glycolipid antigen–recognition properties by Uldrich, Adam P, Patel, Onisha, Cameron, Garth, Pellicci, Daniel G, Day, E Bridie, Sullivan, Lucy C, Kyparissoudis, Konstantinos, Kjer-Nielsen, Lars, Vivian, Julian P, Cao, Benjamin, Brooks, Andrew G, Williams, Spencer J, Illarionov, Petr, Besra, Gurdyal S, Turner, Stephen J, Porcelli, Steven A, McCluskey, James, Smyth, Mark J, Rossjohn, Jamie, Godfrey, Dale I

“…Type I natural killer T cells are characterized by an invariant V α 14-J α 18 T cell antigen receptor α-chain. Godfrey and colleagues describe a population of…”
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Sequential production of interferon-γ by NK1.1+ T cells and natural killer cells is essential for the antimetastatic effect of α-galactosylceramide by Smyth, Mark J., Crowe, Nadine Y., Pellicci, Daniel G., Kyparissoudis, Konstantinos, Kelly, Janice M., Takeda, Kazuyoshi, Yagita, Hideo, Godfrey, Dale I.

“…The antimetastatic effect of the CD1d-binding glycolipid, α-galactosylceramide (α-GalCer), is mediated by NK1.1+T (NKT) cells; however, the mechanisms behind…”
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Glycolipid Antigen Drives Rapid Expansion and Sustained Cytokine Production by NK T Cells by Crowe, Nadine Y, Uldrich, Adam P, Kyparissoudis, Konstantinos, Hammond, Kirsten J. L, Hayakawa, Yoshihiro, Sidobre, Stephane, Keating, Rachael, Kronenberg, Mitchell, Smyth, Mark J, Godfrey, Dale I

“…NKT cells are enigmatic lymphocytes that respond to glycolipid Ags presented by CD1d. Although they are key immunoregulatory cells, with a critical role in…”
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NKT Cell Stimulation with Glycolipid Antigen In Vivo: Costimulation-Dependent Expansion, Bim-Dependent Contraction, and Hyporesponsiveness to Further Antigenic Challenge by Uldrich, Adam P, Crowe, Nadine Y, Kyparissoudis, Konstantinos, Pellicci, Daniel G, Zhan, Yifan, Lew, Andrew M, Bouillet, Philippe, Strasser, Andreas, Smyth, Mark J, Godfrey, Dale I

“…Activation of NKT cells using the glycolipid alpha-galactosylceramide (alpha-GalCer) has availed many investigations into their immunoregulatory and…”
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The glucocorticoid receptor 1A3 promoter correlates with high sensitivity to glucocorticoid‐induced apoptosis in human lymphocytes by Liddicoat, Douglas R, Kyparissoudis, Konstantinos, Berzins, Stuart P, Cole, Timothy J, Godfrey, Dale I

“…Glucocorticoids (GCs) are powerful inhibitors of inflammation and immunity. Although glucocorticoid‐induced cell death (GICD) is an important part of GCs…”
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Distinct roles in NKT cell maturation and function for the different transcription factors in the classical NF-κB pathway by Stankovic, Sanda, Gugasyan, Raffi, Kyparissoudis, Konstantinos, Grumont, Raelene, Banerjee, Ashish, Tsichlis, Philip, Gerondakis, Steve, Godfrey, Dale I

“…The nuclear factor (NF)‐κB signalling pathway is known to be critical for natural killer T (NKT) cell differentiation; however, the role of individual NF‐κB…”
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IL-2/ IL-2 mAb treatment generates prolonged expansion and increased cytokine production by NKT cells (50.42) by Webster, Kylie, Kyparissoudis, Konstantinos, Godfrey, Dale, Sprent, Jonathan

“…Abstract Regulatory T cells can be dramatically boosted in vivo by stimulation with a complex of IL-2 and an IL-2 mAb (JES6-1). The swift 15-fold expansion…”
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The Influence of CD1d in Postselection NKT Cell Maturation and Homeostasis by McNab, Finlay W, Berzins, Stuart P, Pellicci, Daniel G, Kyparissoudis, Konstantinos, Field, Kenneth, Smyth, Mark J, Godfrey, Dale I

“…After being positively selected on CD1d-expressing thymocytes, NKT cells undergo a series of developmental changes that can take place inside or outside the…”
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Congenic Analysis of the NKT Cell Control Gene Nkt2 Implicates the Peroxisomal Protein Pxmp4 by Fletcher, Julie M, Jordan, Margaret A, Snelgrove, Sarah L, Slattery, Robyn M, Dufour, Francois D, Kyparissoudis, Konstantinos, Besra, Gurdyal S, Godfrey, Dale I, Baxter, Alan G

“…Type 1 NKT cells play a critical role in controlling the strength and character of adaptive and innate immune responses. We have previously reported…”
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