Search Results - "Kylhammar, D"

The principal pathways involved in the in vivo modulation of hypoxic pulmonary vasoconstriction, pulmonary arterial remodelling and pulmonary hypertension by Kylhammar, D., Rådegran, G.

“…Hypoxic pulmonary vasoconstriction (HPV) serves to optimize ventilation–perfusion matching in focal hypoxia and thereby enhances pulmonary gas exchange. During…”
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Angiogenic and inflammatory biomarkers for screening and follow-up in patients with pulmonary arterial hypertension by Kylhammar, D, Hesselstrand, R, Nielsen, S, Scheele, C, Rådegran, G

“…Objective: To identify circulating angiogenic and inflammatory biomarkers with potential in screening for pulmonary arterial hypertension (PAH) in systemic…”
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Post systolic shortening by speckle tracking echocardiography as a predictor for cardiovascular events in patients with type 2 diabetes by Hult, L, Kylhammar, D, Engvall, J, Ostgren, C J, Nystrom, F, Blomstrand, P, Hedman, K

“…Abstract Background Post systolic shortening (PSS), measured by speckle tracking echocardiography has emerged as a novel method to evaluate left ventricular…”
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Global longitudinal strain and mechanical dispersion in the general population aged 50-64 years - results from the echocardiography study of the Swedish CArdioPulmonary bioImage Study (SCAPIS) by Kylhammar, D., Hult, Lina, Blomstrand, Peter, Engstrom, G., Johnson, J., Ostgren, C. J., Engvall, J.

“…Background The Swedish CArdioPulmonary bioImage Study (SCAPIS) was initiated to improve understanding of underlying mechanisms in order to prevent…”
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Cyclooxygenase-2 inhibition and thromboxane A2 receptor antagonism attenuate hypoxic pulmonary vasoconstriction in a porcine model by Kylhammar, D., Rådegran, G.

“…Aim Hypoxic pulmonary vasoconstriction (HPV) causes pulmonary hypertension that may lead to right heart failure. We hypothesized that the COX‐2 inhibitor…”
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Baseline hemodynamics and its effect on survival in patients with idiopathic versus CTD-associated pulmonary arterial hypertension: data from the Swedish Pulmonary Arterial Hypertension Register by Hjalmarsson, C., Radegran, G., Kjellstrom, B., Kylhammar, D., Söderberg, Stefan, Bartfay, S. E., Hesselstrand, R.

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The ratio FEV1/FVC and its association to respiratory symptoms—A Swedish general population study by Torén, Kjell, Schiöler, Linus, Lindberg, Anne, Andersson, Anders, Behndig, Annelie F., Bergström, Göran, Blomberg, Anders, Caidahl, Kenneth, Engvall, Jan E., Eriksson, Maria J., Hamrefors, Viktor, Janson, Christer, Kylhammar, David, Lindberg, Eva, Lindén, Anders, Malinovschi, Andrei, Lennart Persson, Hans, Sandelin, Martin, Eriksson Ström, Jonas, Tanash, Hanan, Vikgren, Jenny, Johan Östgren, Carl, Wollmer, Per, Sköld, C. Magnus

“…Chronic airflow limitation (CAL) can be defined as fixed ratio of forced expiratory volume in 1 s (FEV1)/forced vital capacity (FVC) < 0.70 after…”
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sGC stimulation totally reverses hypoxia-induced pulmonary vasoconstriction alone and combined with dual endothelin-receptor blockade in a porcine model by Lundgren, J., Kylhammar, D., Hedelin, P., Rådegran, G.

“…Aim Stimulation of soluble guanylate cyclase (sGC) with BAY 41‐8543 was hypothesized to attenuate acute hypoxic pulmonary vasoconstriction alone and combined…”
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Dual endothelin receptor blockade with tezosentan markedly attenuates hypoxia-induced pulmonary vasoconstriction in a porcine model by Hedelin, P., Kylhammar, D., Rådegran, G.

“…Aim:  Our aim was to test the hypothesis that dual endothelin receptor blockade with tezosentan attenuates hypoxia‐induced pulmonary vasoconstriction. Methods:…”
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Chronic airflow limitation and its relation to respiratory symptoms among ever-smokers and never-smokers: a cross-sectional study by Toren, Kjell, Schiöler, Linus, Lindberg, Anne, Andersson, Anders, Behndig, Annelie F, Bergström, Göran, Blomberg, Anders, Caidahl, Kenneth, Engvall, Jan, Eriksson, Maria, Hamrefors, Viktor, Janson, Christer, Kylhammar, David, Lindberg, Eva, Lindén, Anders, Malinovschi, Andrei, Persson, Hans Lennart, Sandelin, Martin, Eriksson Ström, Jonas, Tanash, Hanan A, Vikgren, Jenny, Östgren, Carl Johan, Wollmer, Per, Sköld, C. Magnus

“…BackgroundThe diagnosis of chronic obstructive pulmonary disease is based on the presence of persistent respiratory symptoms and chronic airflow limitation…”
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A comprehensive risk stratification at early follow-up determines prognosis in pulmonary arterial hypertension by Kylhammar, David, Kjellström, Barbro, Hjalmarsson, Clara, Jansson, Kjell, Nisell, Magnus, Söderberg, Stefan, Wikström, Gerhard, Rådegran, Göran

“…Guidelines recommend a goal-oriented treatment approach in pulmonary arterial hypertension (PAH). The aim is to reach a low-risk profile, as determined by a…”
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What characterizes normotensive individuals with obesity and normal systolic heart function? A descriptive study from the SCAPIS cohort by Korduner, J, Holm Isholth, H, Jujic, A, Engstrom, G, Kylhammar, D, Engvall, J, Magnusson, M, Gottsater, A, Nilsson, P M

“…Abstract Background Heart failure and cardiovascular disease are strongly related to obesity, and the incidence of these conditions shows a linear relationship…”
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Impact of age and comorbidity on risk stratification in idiopathic pulmonary arterial hypertension by Hjalmarsson, Clara, Rådegran, Göran, Kylhammar, David, Rundqvist, Bengt, Multing, Jonas, Nisell, Magnus D, Kjellström, Barbro

“…Recent reports from worldwide pulmonary hypertension registries show a new demographic picture for patients with idiopathic pulmonary arterial hypertension…”
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3075Global longitudinal strain and mechanical dispersion in the general population aged 50–64 years – results from the echocardiography study of the Swedish CArdioPulmonary bioImage Study (SCAPIS) by Kylhammar, D, Hult, L, Blomstrand, P, Engstrom, G, Johnson, J, Ostgren, C J, Engvall, J

“…Abstract Background The Swedish CArdioPulmonary bioImage Study (SCAPIS) was initiated to improve understanding of underlying mechanisms in order to prevent…”
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P3680Baseline hemodynamics and its effect on survival in patients with idiopathic versus CTD-associated pulmonary arterial hypertension: data from the Swedish Pulmonary Arterial Hypertension Register by Hjalmarsson, C, Radegran, G, Kjellstrom, B, Kylhammar, D, Soderberg, S, Bartfay, S E, Hesselstrand, R

“…Abstract Background Patients with CTD-APAH have a worse prognosis than those with IPAH, despite having lower pulmonary vascular resistance at diagnosis…”
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Cyclooxygenase‐2 inhibition and thromboxane A 2 receptor antagonism attenuate hypoxic pulmonary vasoconstriction in a porcine model by Kylhammar, D., Rådegran, G.

“…Abstract Aim Hypoxic pulmonary vasoconstriction ( HPV ) causes pulmonary hypertension that may lead to right heart failure. We hypothesized that the COX ‐2…”
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P3535Cause of death in patients with idiopathic pulmonary arterial hypertension: data from the Swedish pulmonary arterial hypertension registry by Hjalmarsson, C., Rundqvist, B., Multing, J., Kylhammar, D., Radegran, G., Kjellstrom, B.

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Wall shear stress measured with 4D flow CMR correlates with biomarkers of inflammation and collagen synthesis in mild-to-moderate ascending aortic dilation and tricuspid aortic valves by Hammaréus, Filip, Trenti, Chiara, Björck, Hanna M, Engvall, Jan, Lekedal, Hanna, Krzynska-Trzebiatowska, Aleksandra, Kylhammar, David, Lindenberger, Marcus, Lundberg, Anna K, Nilsson, Fredrik, Nilsson, Lennart, Swahn, Eva, Jonasson, Lena, Dyverfeldt, Petter

“…Abstract Aims Understanding the mechanisms underlying ascending aortic dilation is imperative for refined risk stratification of these patients, particularly…”
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D53 THE PROMISED LAND: CLINICAL STUDIES IN PULMONARY HYPERTENSION: Pulmonary Arterial Hypertension (pah) Specific Therapy Induce Changes In L-Arginine And Methylarginines Compared To Baseline Values In Healthy Subjects And Patients With Heart Failure by Sandqvist, A M, Henrohn, D, Kylhammar, D, Lundgren, J, Schneede, J, Rådegran, G, Wikström, G

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Risk stratification in chronic thromboembolic pulmonary hypertension predicts survival by Sandqvist, Anna, Kylhammar, David, Bartfay, Sven-Erik, Hesselstrand, Roger, Hjalmarsson, Clara, Kavianipour, Mohammad, Nisell, Magnus, Rådegran, Göran, Wikström, Gerhard, Kjellström, Barbro, Söderberg, Stefan

“…To investigate if the pulmonary arterial hypertension (PAH) risk assessment tool presented in the 2015 ESC/ERS guidelines is valid for patients with chronic…”
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