Search Results - "Kyle, R R"

Multicellular dynamics and wealth distribution in bacteria by Allison, Kyle R

“…In a variety of infections, bacteria form multicellular communities which contribute to virulence and antibiotic tolerance. The molecular biology of such…”
Get full text

A Randomized Crossover Study Investigating the Running Economy of Highly-Trained Male and Female Distance Runners in Marathon Racing Shoes versus Track Spikes by Barnes, Kyle R., Kilding, Andrew E.

“…Background Running economy represents a complex interplay of physiological and biomechanical factors that are able to adapt chronically through training, or…”
Get full text

Comprehensive genomic analysis identifies novel subtypes and targets of triple-negative breast cancer by Burstein, Matthew D, Tsimelzon, Anna, Poage, Graham M, Covington, Kyle R, Contreras, Alejandro, Fuqua, Suzanne A W, Savage, Michelle I, Osborne, C Kent, Hilsenbeck, Susan G, Chang, Jenny C, Mills, Gordon B, Lau, Ching C, Brown, Powel H

“…Genomic profiling studies suggest that triple-negative breast cancer (TNBC) is a heterogeneous disease. In this study, we sought to define TNBC subtypes and…”
Get full text

Potentially long-lasting effects of the pandemic on scientists by Gao, Jian, Yin, Yian, Myers, Kyle R., Lakhani, Karim R., Wang, Dashun

“…Two surveys of principal investigators conducted between April 2020 and January 2021 reveal that while the COVID-19 pandemic’s initial impacts on scientists’…”
Get full text

Discussion: Diagnosis and Outcomes of 225 Consecutive Cases of Complex Regional Pain Syndrome of the Hand by Eberlin, Kyle R.

Get full text

Effective gene expression prediction from sequence by integrating long-range interactions by Avsec, Žiga, Agarwal, Vikram, Visentin, Daniel, Ledsam, Joseph R., Grabska-Barwinska, Agnieszka, Taylor, Kyle R., Assael, Yannis, Jumper, John, Kohli, Pushmeet, Kelley, David R.

“…How noncoding DNA determines gene expression in different cell types is a major unsolved problem, and critical downstream applications in human genetics depend…”
Get full text

Retention and deformation of the blue phases in liquid crystalline elastomers by Schlafmann, Kyle R., White, Timothy J.

“…The blue phases are observed in highly chiral liquid crystalline compositions that nascently organize into a three-dimensional, crystalline nanostructure. The…”
Get full text

Metabolite-enabled eradication of bacterial persisters by aminoglycosides by Allison, Kyle R., Brynildsen, Mark P., Collins, James J.

“…How metabolic 'helpers' kill persistent pathogens Bacterial cells can enter a dormant 'persister' state that leaves them more resistant to stress conditions,…”
Get full text

Leveraging Big Data for Small Patients: Identifying Maternal and Neonatal Risk Factors for Pediatric Organ Transplant by Jackson, Kyle R.

Get full text

Emerging roles of ER stress and unfolded protein response pathways in skeletal muscle health and disease by Bohnert, Kyle R., McMillan, Joseph D., Kumar, Ashok

“…Skeletal muscle is the most abundant tissue in the human body and can adapt its mass as a consequence of physical activity, metabolism, growth factors, and…”
Get full text

Carbon Nanomaterials in Biosensors: Should You Use Nanotubes or Graphene by Yang, Wenrong, Ratinac, Kyle R, Ringer, Simon P, Thordarson, Pall, Gooding, J. Justin, Braet, Filip

“…From diagnosis of life-threatening diseases to detection of biological agents in warfare or terrorist attacks, biosensors are becoming a critical part of…”
Get full text

Machine learning and conventional statistics: making sense of the differences by Ley, Christophe, Martin, R. Kyle, Pareek, Ayoosh, Groll, Andreas, Seil, Romain, Tischer, Thomas

“…The application of machine learning (ML) to the field of orthopaedic surgery is rapidly increasing, but many surgeons remain unfamiliar with the nuances of…”
Get full text

Endogenous Retrotransposition Activates Oncogenic Pathways in Hepatocellular Carcinoma by Shukla, Ruchi, Upton, Kyle R., Muñoz-Lopez, Martin, Gerhardt, Daniel J., Fisher, Malcolm E., Nguyen, Thu, Brennan, Paul M., Baillie, J. Kenneth, Collino, Agnese, Ghisletti, Serena, Sinha, Shruti, Iannelli, Fabio, Radaelli, Enrico, Dos Santos, Alexandre, Rapoud, Delphine, Guettier, Catherine, Samuel, Didier, Natoli, Gioacchino, Carninci, Piero, Ciccarelli, Francesca D., Garcia-Perez, Jose Luis, Faivre, Jamila, Faulkner, Geoffrey J.

“…LINE-1 (L1) retrotransposons are mobile genetic elements comprising ∼17% of the human genome. New L1 insertions can profoundly alter gene function and cause…”
Get full text

A review of the clinical pharmacology of methamphetamine by Cruickshank, Christopher C., Dyer, Kyle R.

“…ABSTRACT Aims  To examine the literature regarding clinical pharmacokinetics, direct effects and adverse clinical outcomes associated with methamphetamine use…”
Get full text

Clinical characteristics, pathophysiology, and management of noncentral nervous system cancer‐related cognitive impairment in adults by Wefel, Jeffrey S., Kesler, Shelli R., Noll, Kyle R., Schagen, Sanne B.

“…Answer questions and earn CME/CNE Over the past few decades, a body of research has emerged confirming what many adult patients with noncentral nervous system…”
Get full text

Editorial Commentary: The Medial Patellofemoral Ligament Is Not Isometric and Anatomic Reconstruction Is Important, But Just a Small Piece of the Patellar Instability Puzzle by Duchman, Kyle R.

“…Medial patellofemoral ligament (MPFL) reconstruction has proven to be a reliable procedure to reduce patellar instability events in patients with recurrent…”
Get full text

Long-Time Scale Simulations Reveal Key Dynamics That Drive the Onset of the N State in the Proteorhodopsin Photocycle by Billings, Kyle R., Faramarzi, Sadegh, Mertz, Blake

“…Proteorhodopsin (PR) is a microbial proton pump that plays a significant role in phototrophy of bacteria in marine environments. Fundamental understanding of…”
Get full text

Resuscitation dynamics reveal persister partitioning after antibiotic treatment by Fang, Xin, Allison, Kyle R

“…Bacteria can survive antibiotics by forming dormant, drug‐tolerant persisters. Persisters can resuscitate from dormancy after treatment and prolong infections…”
Get full text

Mechanism of actin filament severing and capping by gelsolin by Barrie, Kyle R, Rebowski, Grzegorz, Dominguez, Roberto

“…Gelsolin is the prototypical member of a family of Ca -activated F-actin severing and capping proteins. Here we report structures of Ca -bound human gelsolin…”
Get full text

Surgical Algorithm for Neuroma Management: A Changing Treatment Paradigm by Eberlin, Kyle R., Ducic, Ivica

“…Successful treatment of the painful neuroma is a particular challenge to the nerve surgeon. Historically, symptomatic neuromas have primarily been treated with…”
Get full text