Search Results - "Kyle, Andrew F."
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Synthesis of macrocyclic natural products by catalyst-controlled stereoselective ring-closing metathesis
Published in Nature (London) (03-11-2011)“…Stereoselective ring closure There are a large number of chemical transformations in which alkenes act as the reactants and/or products of the reaction…”
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Journal Article -
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Efficient and Selective Formation of Macrocyclic Disubstituted Z Alkenes by Ring-Closing Metathesis (RCM) Reactions Catalyzed by Mo- or W-Based Monoaryloxide Pyrrolide (MAP) Complexes: Applications to Total Syntheses of Epilachnene, Yuzu Lactone, Ambrettolide, Epothilone C, and Nakadomarin A
Published in Chemistry : a European journal (18-02-2013)“…The first broadly applicable set of protocols for efficient Z‐selective formation of macrocyclic disubstituted alkenes through catalytic ring‐closing…”
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Journal Article -
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Total synthesis of (−)-nakadomarin A: alkyne ring-closing metathesis
Published in Tetrahedron letters (16-11-2011)“…A 13-step, highly stereoselective synthesis of (−)-nakadomarin A has been achieved using the combination of a bifunctional organocatalyst controlled Michael…”
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Journal Article -
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Catalytic Asymmetric Alkylation Reactions for the Construction of Protected Ethylene-Amino and Propylene-Amino Motifs Attached to Quaternary Stereocentres
Published in Chemistry : a European journal (25-02-2013)“…An efficient catalytic and stereoselective method for the direct construction of protected ethylene‐amino and propylene‐amino scaffolds attached to quaternary…”
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Journal Article -
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Applications of NHC-mediated O- to C-carboxyl transfer: synthesis of (±)- N-benzyl-coerulescine and (±)-horsfiline
Published in Tetrahedron (22-05-2010)“…NHC-promoted O- to C-carboxyl transfer of 3-allyl indolyl phenyl carbonates generates 3-allyl-3-phenoxycarbonyl-oxindoles with good catalytic efficiency, which…”
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Journal Article -
6
Total synthesis of (-)-nakadomarin A
Published in Chemical communications (Cambridge, England) (28-09-2011)“…A highly diastereoselective bifunctional organocatalyst controlled Michael addition, a nitro-Mannich/lactamization cascade, a furan N-acyliminium cyclisation,…”
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Journal Article -
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Total synthesis of (–)-nakadomarin A and an approach to the diazatricyclic core of the madangamines
Published 01-01-2012“…This dissertation describes work towards two marine alkaloid natural products of the manzamine family. The total synthesis of (–)-nakadomarin A, via two…”
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Dissertation -
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Total synthesis of (–)-nakadomarin a and an approach to the diazatricyclic core of the madangamines
Published 01-01-2012“…This dissertation describes work towards two marine alkaloid natural products of the manzamine family. The total synthesis of (–)-nakadomarin A, via two…”
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Dissertation