Search Results - "Kyjacova, L"
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Radiotherapy-induced plasticity of prostate cancer mobilizes stem-like non-adherent, Erk signaling-dependent cells
Published in Cell death and differentiation (01-06-2015)“…Fractionated ionizing radiation combined with surgery or hormone therapy represents the first-choice treatment for medium to high-risk localized prostate…”
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2
IFNγ induces oxidative stress, DNA damage and tumor cell senescence via TGFβ/SMAD signaling-dependent induction of Nox4 and suppression of ANT2
Published in Oncogene (10-03-2016)“…Cellular senescence provides a biological barrier against tumor progression, often associated with oncogene-induced replication and/or oxidative stress,…”
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3
EACR-MRS conference on Seed and Soil: In Vivo Models of Metastasis
Published in Clinical & experimental metastasis (01-12-2017)“…New experimental tools are urgently required to better understand the metastatic process. The importance of such tools is underscored by the fact that many…”
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4
Hyaluronic acid-CD44 interactions promote BMP4/7-dependent Id1/3 expression in melanoma cells
Published in Scientific reports (08-10-2018)“…BMP4/7-dependent expression of inhibitor of differentiation/DNA binding (Id) proteins 1 and 3 has been implicated in tumor progression and poor prognosis of…”
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5
IFN[gamma] induces oxidative stress, DNA damage and tumor cell senescence via TGF[beta]/SMAD signaling-dependent induction of Nox4 and suppression of ANT2
Published in Oncogene (10-03-2016)“…Cellular senescence provides a biological barrier against tumor progression, often associated with oncogene-induced replication and/or oxidative stress,…”
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6
Two-Step Mechanism of Cellular Uptake of Cationic Gold Nanoparticles Modified by (16-Mercaptohexadecyl)trimethylammonium Bromide
Published in Bioconjugate chemistry (19-10-2016)“…Cationic colloidal gold nanorods (GNRs) have a great potential as a theranostic tool for diverse medical applications. GNRs’ properties such as cellular…”
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Induction, regulation and roles of neural adhesion molecule L1CAM in cellular senescence
Published in Aging (Albany, NY.) (28-03-2018)“…Aging involves tissue accumulation of senescent cells (SC) whose elimination through senolytic approaches may evoke organismal rejuvenation. SC also contribute…”
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Interferon‐regulated suprabasin is essential for stress‐induced stem‐like cell conversion and therapy resistance of human malignancies
Published in Molecular oncology (01-07-2019)“…Radiation and chemotherapy represent standard‐of‐care cancer treatments. However, most patients eventually experience tumour recurrence, treatment failure and…”
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Tumor growth accelerated by chemotherapy-induced senescent cells is suppressed by treatment with IL-12 producing cellular vaccines
Published in Oncotarget (23-08-2016)“…Standard-of-care chemo- or radio-therapy can induce, besides tumor cell death, also tumor cell senescence. While senescence is considered to be a principal…”
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