Search Results - "Kyei, Stephen K"
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Microbial killing by NK cells
Published in Journal of leukocyte biology (01-06-2019)“…It is now evident that NK cells kill bacteria, fungi, and parasites in addition to tumor and virus‐infected cells. In addition to a number of recent…”
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The NK Receptor NKp30 Mediates Direct Fungal Recognition and Killing and Is Diminished in NK Cells from HIV-Infected Patients
Published in Cell host & microbe (16-10-2013)“…Natural killer (NK) cells are a subset of immune effectors that directly bind and kill fungi via a perforin-dependent mechanism. The receptor mediating this…”
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Cryptococcus gattii Capsule Blocks Surface Recognition Required for Dendritic Cell Maturation Independent of Internalization and Antigen Processing
Published in The Journal of immunology (1950) (01-02-2016)“…Cryptococcus gattii is an emerging fungal pathogen on the west coast of Canada and the United States that causes a potentially fatal infection in otherwise…”
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Mechanisms by Which Interleukin-12 Corrects Defective NK Cell Anticryptococcal Activity in HIV-Infected Patients
Published in mBio (23-08-2016)“…Cryptococcus neoformans is a pathogenic yeast and a leading cause of life-threatening meningitis in AIDS patients. Natural killer (NK) cells are important…”
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Leukotriene B4-Mediated Neutrophil Recruitment Causes Pulmonary Capillaritis during Lethal Fungal Sepsis
Published in Cell host & microbe (10-01-2018)“…Candida albicans bloodstream infection causes fungal septicaemia and death in over half of afflicted patients. Polymorphonuclear leukocytes (PMN) mediate…”
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Ras-related C3 Botulinum Toxin Substrate (Rac) and Src Family Kinases (SFK) Are Proximal and Essential for Phosphatidylinositol 3-Kinase (PI3K) Activation in Natural Killer (NK) Cell-mediated Direct Cytotoxicity against Cryptococcus neoformans
Published in The Journal of biological chemistry (25-03-2016)“…The activity of Rac in leukocytes is essential for immunity. However, its role in NK cell-mediated anti-microbial signaling remains unclear. In this study, we…”
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Efficient Enrichment of Functional ILC Subsets from Human PBMC by Immunomagnetic Selection
Published in The Journal of immunology (1950) (01-05-2018)“…Abstract Innate lymphoid cells (ILCs) are exceedingly rare but important regulators of homeostatic and disease-associated immune processes. The frequency of…”
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Efficient isolation of particle-free human ILC2s from peripheral blood mononuclear cells
Published in The Journal of immunology (1950) (01-05-2018)“…Abstract Group 2 innate lymphoid cells (ILC2s) have important roles in type-2 immune responses and are implicated in allergies, asthma, helminth infections and…”
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Fast and efficient enrichment of functional ILC2 from human whole blood
Published in The Journal of immunology (1950) (01-05-2016)“…Abstract Group 2 innate lymphoid cells (ILC2) are a functionally distinct subset of recently identified immune cells with important roles in type-2…”
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Immunomagnetic enrichment of human ILC2 cells from peripheral blood leukopak
Published in The Journal of immunology (1950) (01-05-2016)“…Abstract Group 2 innate lymphoid cells (ILC2s) are essential for airway tissue repair, protection against helminth infection, metabolic homeostasis, and the…”
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