Search Results - "Kwon, Sang‐Mo"
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Tissue Engineered Bio‐Blood‐Vessels Constructed Using a Tissue‐Specific Bioink and 3D Coaxial Cell Printing Technique: A Novel Therapy for Ischemic Disease
Published in Advanced functional materials (06-09-2017)“…Endothelial progenitor cells (EPCs) are a promising cell source for the treatment of several ischemic diseases for their potentials in neovascularization…”
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Pivotal Roles of Peroxisome Proliferator-Activated Receptors (PPARs) and Their Signal Cascade for Cellular and Whole-Body Energy Homeostasis
Published in International journal of molecular sciences (22-03-2018)“…Peroxisome proliferator-activated receptors (PPARs), members of the nuclear receptor superfamily, are important in whole-body energy metabolism. PPARs are…”
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Tailoring mechanical properties of decellularized extracellular matrix bioink by vitamin B2-induced photo-crosslinking
Published in Acta biomaterialia (01-03-2016)“…[Display omitted] We have developed two-step process that uses sequential vitamin B2-induced UVA crosslinking and thermal gelation to solidify decellularized…”
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CD276 (B7‐H3) Maintains Proliferation and Regulates Differentiation in Angiogenic Function in Late Endothelial Progenitor Cells
Published in Stem cells (Dayton, Ohio) (01-03-2019)“…Endothelial progenitor cells (EPCs) provide an important source of recovery from blood vessel dysfunction. Late EPCs (LEPCs) are circulating blood cells that…”
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Vascular Endothelial Growth Factor Biology and Its Potential as a Therapeutic Target in Rheumatic Diseases
Published in International journal of molecular sciences (20-05-2021)“…Rheumatic diseases constitute a diversified group of diseases distinguished by arthritis and often involve other organs. The affected individual has low…”
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The Sulfated Polysaccharide Fucoidan Rescues Senescence of Endothelial Colony‐Forming Cells for Ischemic Repair
Published in Stem cells (Dayton, Ohio) (01-06-2015)“…The efficacy of cell therapy using endothelial colony‐forming cells (ECFCs) in the treatment of ischemia is limited by the replicative senescence of isolated…”
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SDF‐1/CXCR4 Axis in Tie2‐Lineage Cells Including Endothelial Progenitor Cells Contributes to Bone Fracture Healing
Published in Journal of bone and mineral research (01-01-2015)“…ABSTRACT CXC chemokine receptor 4 (CXCR4) is a specific receptor for stromal‐derived‐factor 1 (SDF‐1). SDF‐1/CXCR4 interaction is reported to play an important…”
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Therapeutic Strategies for Oxidative Stress-Related Cardiovascular Diseases: Removal of Excess Reactive Oxygen Species in Adult Stem Cells
Published in Oxidative medicine and cellular longevity (01-01-2016)“…Accumulating evidence indicates that acute and chronic uncontrolled overproduction of oxidative stress-related factors including reactive oxygen species (ROS)…”
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Artificial Neural Processing-Driven Bioelectronic Nose for the Diagnosis of Diabetes and Its Complications
Published in Advanced healthcare materials (01-10-2023)“…Diabetes and its complications affect the younger population and are associated with a high mortality rate; however, early diagnosis can contribute to the…”
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Tauroursodeoxycholic Acid, a Bile Acid, Promotes Blood Vessel Repair by Recruiting Vasculogenic Progenitor Cells
Published in Stem cells (Dayton, Ohio) (01-03-2015)“…Although serum bile acid concentrations are approximately 10 µM in healthy subjects, the crosstalk between the biliary system and vascular repair has never…”
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Development of Biocompatible 3D-Printed Artificial Blood Vessels through Multidimensional Approaches
Published in Journal of functional biomaterials (01-10-2023)“…Within the human body, the intricate network of blood vessels plays a pivotal role in transporting nutrients and oxygen and maintaining homeostasis…”
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Pharmacological inhibition of mTOR attenuates replicative cell senescence and improves cellular function via regulating the STAT3-PIM1 axis in human cardiac progenitor cells
Published in Experimental & molecular medicine (01-04-2020)“…The mammalian target of rapamycin (mTOR) signaling pathway efficiently regulates the energy state of cells and maintains tissue homeostasis. Dysregulation of…”
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The Protective Role of Glutathione against Doxorubicin-Induced Cardiotoxicity in Human Cardiac Progenitor Cells
Published in International journal of molecular sciences (28-07-2023)“…This study investigated the protective effect of glutathione (GSH), an antioxidant drug, against doxorubicin (DOX)-induced cardiotoxicity. Human cardiac…”
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Anti-Tumor Efficacy of Oleuropein-Loaded ZnO/Au Mesoporous Silica Nanoparticle in 5-FU-Resistant Colorectal Cancer Cells
Published in International journal of nanomedicine (01-01-2024)“…5-fluorouracil (5-FU) is a first-line chemotherapeutic agent used to treat colorectal cancer (CRC). However, 5-FU induces drug resistance and activation of…”
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Promising Therapeutic Strategies for Mesenchymal Stem Cell-Based Cardiovascular Regeneration: From Cell Priming to Tissue Engineering
Published in Stem Cells International (01-01-2017)“…The primary cause of death among chronic diseases worldwide is ischemic cardiovascular diseases, such as stroke and myocardial infarction. Recent evidence…”
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CD34+ cells represent highly functional endothelial progenitor cells in murine bone marrow
Published in PloS one (31-05-2011)“…Endothelial progenitor cells (EPCs) were shown to have angiogenic potential contributing to neovascularization. However, a clear definition of mouse EPCs by…”
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MHY2233 Attenuates Replicative Cellular Senescence in Human Endothelial Progenitor Cells via SIRT1 Signaling
Published in Oxidative medicine and cellular longevity (01-01-2019)“…Cardiovascular diseases (CVDs) are a major cause of death worldwide. Due to the prevalence of many side effects and incomplete recovery from pharmacotherapies,…”
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Therapeutic Angiogenesis via Solar Cell-Facilitated Electrical Stimulation
Published in ACS applied materials & interfaces (08-11-2017)“…Cell therapy has been suggested as a treatment modality for ischemic diseases, but the poor survival and engraftment of implanted cells limit its therapeutic…”
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Perspectives on Stem Cell Therapy for Cardiac Regeneration: Advances and Challenges
Published in Circulation Journal (2012)“…Ischemic heart disease (IHD) accelerates cardiomyocyte loss, but the developing stem cell research could be useful for regenerating a variety of tissue cells,…”
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Specific Jagged-1 Signal From Bone Marrow Microenvironment Is Required for Endothelial Progenitor Cell Development for Neovascularization
Published in Circulation (New York, N.Y.) (08-07-2008)“…Despite accumulating evidence that proves the pivotal role of endothelial progenitor cells (EPCs) in ischemic neovascularization, the key signaling cascade…”
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