Search Results - "Kwon, Oh Kwang"
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First profiling of lysine crotonylation of myofilament proteins and ribosomal proteins in zebrafish embryos
Published in Scientific reports (26-02-2018)“…Zebrafish embryos are translucent and develop rapidly in individual eggs ex utero ; they are widely used as models for embryogenesis and organ development for…”
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Dynamic Competing Histone H4 K5K8 Acetylation and Butyrylation Are Hallmarks of Highly Active Gene Promoters
Published in Molecular cell (21-04-2016)“…Recently discovered histone lysine acylation marks increase the functional diversity of nucleosomes well beyond acetylation. Here, we focus on histone…”
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Characterization of hyperglycemia due to sub-chronic administration of red ginseng extract via comparative global proteomic analysis
Published in Scientific reports (11-06-2021)“…Ginseng ( Panax ginseng Meyer) is commonly used as an herbal remedy worldwide. Few studies have explored the possible physiological changes in the liver…”
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Metabolic Regulation of Gene Expression by Histone Lysine β-Hydroxybutyrylation
Published in Molecular cell (21-04-2016)“…Here we report the identification and verification of a β-hydroxybutyrate-derived protein modification, lysine β-hydroxybutyrylation (Kbhb), as a new type of…”
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Profiling of Histidine Phosphoproteome in Danio rerio by TiO2 Enrichment
Published in Proteomics (Weinheim) (01-05-2019)“…Histidine phosphorylation is a reversible post‐translational modification that is known to regulate signal transduction in prokaryotes. However, functional…”
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Deacetylation of XBP1s by sirtuin 6 confers resistance to ER stress-induced hepatic steatosis
Published in Experimental & molecular medicine (20-09-2019)“…The active spliced form of X-box-binding protein 1 (XBP1s) is a key modulator of ER stress, but the functional role of its post-translational modification…”
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LDHA Desuccinylase Sirtuin 5 as A Novel Cancer Metastatic Stimulator in Aggressive Prostate Cancer
Published in Genomics, proteomics & bioinformatics (01-02-2023)“…Prostate cancer (PCa) is the most commonly diagnosed genital cancer in men worldwide. Around 80% of the patients who developed advanced PCa suffered from bone…”
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Comparative Proteomic Analysis Reveals the Upregulation of Ketogenesis in Cardiomyocytes Differentiated from Induced Pluripotent Stem Cells
Published in Proteomics (Weinheim) (01-04-2019)“…Diverse metabolic pathways, such as the tricarboxylic acid cycle, pyruvate metabolism, and oxidative phosphorylation, regulate the differentiation of induced…”
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Mechanism Investigation of Rifampicin-Induced Liver Injury Using Comparative Toxicoproteomics in Mice
Published in International journal of molecular sciences (02-07-2017)“…Tuberculosis is one of the top causes of death among curable infectious diseases; it is an airborne infectious disease that killed 1.1 million people worldwide…”
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Proteomics approach to identify novel metastatic bone markers from the secretome of PC‐3 prostate cancer cells
Published in Electrophoresis (01-10-2017)“…Prostate cancer is the leading type of cancer diagnosed, and the most frequent cause of worldwide male cancer‐related deaths annually. The limitations of…”
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Secretome profiling of PC3/nKR cells, a novel highly migrating prostate cancer subline derived from PC3 cells
Published in PloS one (12-08-2019)“…Prostate cancer (PCa) is the most common cancer among men worldwide. Most PCa cases are not fatal; however, the outlook is poor when PCa spreads to another…”
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Investigation of nonalcoholic fatty liver disease-induced drug metabolism by comparative global toxicoproteomics
Published in Toxicology and applied pharmacology (01-08-2018)“…Non-alcoholic fatty liver disease (NAFLD) includes conditions such as steatosis, non-alcoholic steatohepatitis, and ultimately hepatocellular carcinoma…”
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Quantitative Proteomic Analysis of Changes Related to Age and Calorie Restriction in Rat Liver Tissue
Published in Proteomics (Weinheim) (01-03-2018)“…Calorie restriction (CR) is the most frequently studied mechanism for increasing longevity, protecting against stress, and delaying age‐associated diseases…”
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Correction: Secretome profiling of PC3/nKR cells, a novel highly migrating prostate cancer subline derived from PC3 cells
Published in PloS one (13-09-2019)“…[This corrects the article DOI: 10.1371/journal.pone.0220807.]…”
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Role of moesin in HMGB1-stimulated severe inflammatory responses
Published in Thrombosis and haemostasis (01-08-2015)“…Sepsis is a life-threatening condition that arises when the body's response to infection causes systemic inflammation. High-mobility group box 1 (HMGB1), as a…”
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A Comparison of the In Vitro Inhibitory Effects of Thelephoric Acid and SKF-525A on Human Cytochrome P450 Activity
Published in Biomolecules & therapeutics (30-03-2014)“…Thelephoric acid is an antioxidant produced by the hydrolysis of polyozellin, which is isolated from Polyozellus multiplex. In thepresent study, the inhibitory…”
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Global proteomic analysis of lysine acetylation in zebrafish (Danio rerio) embryos
Published in Electrophoresis (01-12-2016)“…Lysine acetylation is an important post‐translational modification (PTM). Since the development of MS‐based proteomics technology, important roles of lysine…”
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Multi-generational impacts of organic contaminated stream water on Daphnia magna: A combined proteomics, epigenetics and ecotoxicity approach
Published in Environmental pollution (1987) (01-06-2019)“…The present study aimed to elucidate the mechanisms of organismal sensitivity and/or physiological adaptation in the contaminated water environment…”
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Sirtuin 6 in preosteoclasts suppresses age- and estrogen deficiency-related bone loss by stabilizing estrogen receptor α
Published in Cell death and differentiation (01-11-2019)“…Emerging evidence indicates that estrogen receptor (ER) α is an important modulator of bone homeostasis, which occurs partly by promoting osteoclast apoptosis…”
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Global Proteomic Analysis of Lysine Succinylation in Zebrafish (Danio rerio)
Published in Journal of proteome research (04-10-2019)“…Lysine succinylation (Ksu) is a novel identified post-translational modification that is conserved from prokaryotes to eukaryotes. As a kind of acylation, Ksu…”
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