Search Results - "Kwon, Jun Hyung"
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The Next Generation COVID‐19 Antiviral; Niclosamide‐Based Inorganic Nanohybrid System Kills SARS‐CoV‐2
Published in Small (Weinheim an der Bergstrasse, Germany) (01-09-2024)“…The coronavirus disease 2019 (COVID‐19) pandemic is a serious global threat with surging new variants of concern. Although global vaccinations have slowed the…”
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Sensitive Detection of SARS-CoV‑2 Using a SERS-Based Aptasensor
Published in ACS sensors (25-06-2021)“…We developed a new surface-enhanced Raman scattering (SERS)-based aptasensor platform capable of quantifying severe acute respiratory syndrome coronavirus 2…”
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Advancing SARS‐CoV‐2 Variant Detection with High Affinity Monoclonal Antibodies and Plasmonic Nanostructure
Published in Advanced functional materials (01-11-2024)“…A nanoplasmonic biosensor for the precise detection of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) by leveraging advances in nanostructured…”
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Ocular tropism of SARS-CoV-2 in animal models with retinal inflammation via neuronal invasion following intranasal inoculation
Published in Nature communications (12-12-2022)“…Although ocular manifestations are reported in patients with COVID-19, consensus on ocular tropism of SARS-CoV-2 is lacking. Here, we infect K18-hACE2…”
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Native High-Density Lipoproteins (HDL) with Higher Paraoxonase Exerts a Potent Antiviral Effect against SARS-CoV-2 (COVID-19), While Glycated HDL Lost the Antiviral Activity
Published in Antioxidants (01-02-2021)“…Human high-density lipoproteins (HDL) show a broad spectrum of antiviral activity in terms of anti-infection. Although many reports have pointed out a…”
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Chemically-defined and scalable culture system for intestinal stem cells derived from human intestinal organoids
Published in Nature communications (27-01-2024)“…Three-dimensional human intestinal organoids (hIO) are widely used as a platform for biological and biomedical research. However, reproducibility and…”
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4‐Hydroxycinnamic acid suppresses airway inflammation and mucus hypersecretion in allergic asthma induced by ovalbumin challenge
Published in Phytotherapy research (01-03-2020)“…In this study, we investigated whether 4‐hydroxycinnamic acid (HA) has a palliative effect on asthmatic inflammatory responses using a mouse model of ovalbumin…”
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WGA-M001, a Mixture of Total Extracts of Tagetes erecta and Ocimum basilicum , Synergistically Alleviates Cartilage Destruction by Inhibiting ERK and NF-κB Signaling
Published in International journal of molecular sciences (14-12-2023)“…and are medicinal plants that exhibit anti-inflammatory effects against various diseases. However, their individual and combined effects on osteoarthritis (OA)…”
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Enhanced binding and inhibition of SARS‐CoV‐2 by a plant‐derived ACE2 protein containing a fused mu tailpiece
Published in Biotechnology journal (01-01-2024)“…Infectious diseases such as Coronavirus disease 2019 (COVID‐19) and Middle East respiratory syndrome (MERS) present an increasingly persistent crisis in many…”
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Myristica fragrans Extract Inhibits Platelet Desialylation and Activation to Ameliorate Sepsis-Associated Thrombocytopenia in a Murine CLP-Induced Sepsis Model
Published in International journal of molecular sciences (16-05-2023)“…Sepsis, characterized by an uncontrolled host inflammatory response to infections, remains a leading cause of death in critically ill patients worldwide…”
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Immunomodulation by extracellular vesicle-like nanoparticles from marine macroalgae Sargassum fusiforme: Enhancing Type 1 T helper and cytotoxic T lymphocyte-mediated immune responses
Published in Journal of functional foods (01-01-2024)“…[Display omitted] •SF-NPs stimulate the maturation of DCs through the MAPK and NF-kB signaling pathways.•SF-NPs-primed DCs drive robust Th1 dominance and…”
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Potential for transmission of naturally mutated H10N1 avian influenza virus to mammalian hosts and causing severe pulmonary disease
Published in Frontiers in microbiology (12-09-2023)“…Subtype H10 avian influenza viruses (AIV) are distributed worldwide in wild aquatic birds, and can infect humans and several other mammalian species. In the…”
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Abietane Diterpenoids Isolated from Torreya nucifera Disrupt Replication of Influenza Virus by Blocking the Phosphatidylinositol-3-Kinase (PI3K)-Akt and ERK Signaling Pathway
Published in Current issues in molecular biology (09-03-2023)“…Although vaccines and antiviral drugs are available, influenza viruses continue to pose a significant threat to vulnerable populations globally. With the…”
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Nutraceutical potential of exosome-like nanoparticles derived from Boehmeria japonica in inflammatory bowel disease
Published in Journal of functional foods (01-01-2024)“…[Display omitted] •Nanoparticles from Boehmeria japonica (BJ-NPs) show promise in treating IBD.•BJ-NPs induced IL-10 in dendritic cells, suppressing…”
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Unfavorable effect of high postoperative fluid balance on outcome of pancreaticoduodenectomy
Published in Annals of surgical treatment and research (01-03-2022)“…Despite the many efforts to overcome postoperative complications, pancreaticoduodenectomy (PD) is still accompanied with considerable concerns of lethal…”
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Design, synthesis, and evaluation of curcumin analogues as potential inhibitors of bacterial sialidase
Published in Journal of enzyme inhibition and medicinal chemistry (01-01-2018)“…Sialidases are key virulence factors that remove sialic acid from the host cell surface glycan, unmasking receptors that facilitate bacterial adherence and…”
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Preventive Effect of Garlic Oil and Its Organosulfur Component Diallyl-Disulfide on Cigarette Smoke-Induced Airway Inflammation in Mice
Published in Nutrients (04-11-2018)“…Garlic ( ) has traditionally been used as a medicinal food and exhibits various beneficial activities, such as antitumor, antimicrobial, hypolipidemic,…”
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Oleanolic Acid Acetate Alleviates Symptoms of Experimental Autoimmune Encephalomyelitis in Mice by Regulating Toll-Like Receptor 2 Signaling
Published in Frontiers in pharmacology (03-09-2020)“…Toll-like receptor 2 (TLR2) is expressed by several immune cells in the central nervous system and plays an important role in neuroinflammation. TLR2…”
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Both α2,3- and α2,6-linked sialic acids on O-linked glycoproteins act as functional receptors for porcine Sapovirus
Published in PLoS pathogens (05-06-2014)“…Sapovirus, a member of the Caliciviridae family, is an important cause of acute gastroenteritis in humans and pigs. Currently, the porcine sapovirus (PSaV)…”
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