Search Results - "Kwon, HyockJoo"
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Molecular Determinants of GS-9620-Dependent TLR7 Activation
Published in PloS one (19-01-2016)“…GS-9620 is an orally administered agonist of Toll-like receptor (TLR)7 currently being evaluated in clinical studies for the treatment of chronic HBV and HIV…”
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Biochemical characterization of recombinant influenza A polymerase heterotrimer complex: Polymerase activity and mechanisms of action of nucleotide analogs
Published in PloS one (11-10-2017)“…Influenza polymerase is a heterotrimer protein with both endonuclease and RNA-dependent RNA polymerase (RdRp) activity. It plays a critical role in viral RNA…”
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Journal Article -
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Biochemical characterization of recombinant influenza A polymerase heterotrimer complex: Endonuclease activity and evaluation of inhibitors
Published in PloS one (15-08-2017)“…Influenza polymerase is a heterotrimer composed of polymerase acidic protein A (PA) and basic proteins 1 (PB1) and 2 (PB2). The endonuclease active site,…”
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Molecular Determinants of GS-9620-Dependent TLR7 Activation: e0146835
Published in PloS one (01-01-2016)“…GS-9620 is an orally administered agonist of Toll-like receptor (TLR)7 currently being evaluated in clinical studies for the treatment of chronic HBV and HIV…”
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Journal Article