Search Results - "Kwon, Glen S"

Production of paclitaxel-loaded PEG-b-PLA micelles using PEG for drug loading and freeze-drying by Rasoulianboroujeni, Morteza, Repp, Lauren, Lee, Hye Jin, Kwon, Glen S.

“…A new approach named PEG-assist is introduced for the production of drug-loaded polymeric micelles. The method is based on the use of PEG as the non-selective…”
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Stereocomplex Prodrugs of Oligo(lactic acid) n ‑Gemcitabine in Poly(ethylene glycol)-block-poly(d,l‑lactic acid) Micelles for Improved Physical Stability and Enhanced Antitumor Efficacy by Tam, Yu Tong, Huang, Chengbin, Poellmann, Michael, Kwon, Glen S

“…Herein we demonstrate the formation of stereocomplex prodrugs of oligo­(l-lactic acid) n -gemcitabine (o­(LLA) n -GEM) and oligo­(d-lactic acid) n -gemcitabine…”
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Polymeric Micelles for Neoadjuvant Cancer Therapy and Tumor-Primed Optical Imaging by Cho, Hyunah, Kwon, Glen S

“…Poly(ethylene glycol)-block-poly(d,l-lactic acid) (PEG-b-PLA) micelles act as a 3-in-1 nanocontainer for three poorly water-soluble drugs–paclitaxel,…”
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Mixed polymeric micelles for combination cancer chemotherapy through the concurrent delivery of multiple chemotherapeutic agents by Bae, Younsoo, Diezi, Thomas A., Zhao, Anni, Kwon, Glen S.

“…As a novel drug nanocarrier for combination delivery of multiple anticancer agents, mixed polymeric micelles were developed and characterized in this study. A…”
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Amphiphilic block copolymers for drug delivery by Adams, Monica L, Lavasanifar, Afsaneh, Kwon, Glen S

“…Amphiphilic block copolymers (ABCs) have been used extensively in pharmaceutical applications ranging from sustained-release technologies to gene delivery. The…”
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Polymeric micelle nanocarriers in cancer research by Shin, Dae Hwan, Tam, Yu Tong, Kwon, Glen S.

“…Amphiphilic block copolymers (ABCs) assemble into a spherical nanoscopic supramolecular core/shell nanostructure termed a polymeric micelle that has been…”
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PEGylated pUR4/FUD peptide inhibitor of fibronectin fibrillogenesis decreases fibrosis in murine Unilateral Ureteral Obstruction model of kidney disease by Tomasini-Johansson, Bianca R, Zbyszynski, Pawel W, Toraason, Inger, Peters, Donna M, Kwon, Glen S

“…Fibronectin is a blood and extracellular matrix glycoprotein that plays important roles in wound healing and fibrosis since it controls the deposition of…”
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In vivo cancer imaging by poly(ethylene glycol)- b -poly(ɛ-caprolactone) micelles containing a near-infrared probe by Cho, Hyunah, MS, Indig, Guilherme L., PhD, Weichert, Jamey, PhD, Shin, Ho-Chul, MS, Kwon, Glen S., PhD

“…Abstract Noninvasive near-infrared (NIR) fluorescence imaging is a promising technique for the intraoperative assessment of solid tumor removal. We…”
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A 3-in-1 Polymeric Micelle Nanocontainer for Poorly Water-Soluble Drugs by Shin, Ho-Chul, Alani, Adam W. G, Cho, Hyunah, Bae, Younsoo, Kolesar, Jill M, Kwon, Glen S

“…Poly(ethylene glycol)-block-poly(d,l-lactic acid) (PEG-b-PLA) micelles have a proven capacity for drug solubilization and have entered phase III clinical…”
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PEG-b-PLA micelles and PLGA-b-PEG-b-PLGA sol–gels for drug delivery by Cho, Hyunah, Gao, Jieming, Kwon, Glen S.

“…Poly(ethylene glycol)-block-poly(D,L-lactic acid) (PEG-b-PLA) micelles and poly(D,L-lactic-co-glycolic acid)-block-polyethylene…”
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Poly(ethylene glycol)-b-Poly(ε-caprolactone) and PEG-Phospholipid Form Stable Mixed Micelles in Aqueous Media by Vakil, Ronak, Kwon, Glen S

“…Novel mixed polymeric micelles formed from biocompatible polymers, poly(ethylene glycol)-b-poly(ε-caprolactone) (PEG5000-b-PCL x ) and…”
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Enhanced Stability of PEG-block-poly(N-hexyl stearate l-aspartamide) Micelles in the Presence of Serum Proteins by Diezi, Thomas A, Bae, Younsoo, Kwon, Glen S

“…Polyethylene glycol-phospholipid micelles form a major class of nanocarriers in pharmacy and medicine due to proven capability in drug solubilization,…”
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Cell‐Based Delivery Systems: Emerging Carriers for Immunotherapy by Li, Zhaoting, Wang, Yixin, Ding, Yingyue, Repp, Lauren, Kwon, Glen S., Hu, Quanyin

“…Immunotherapy is leading a paradigm shift in the treatment of various diseases, including tumors, auto‐immune diseases, and infectious diseases. However, the…”
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In vitro release of the mTOR inhibitor rapamycin from poly(ethylene glycol)-b-poly(ε-caprolactone) micelles by Forrest, M. Laird, Won, Chee-Youb, Malick, A. Waseem, Kwon, Glen S.

“…An injectable formulation of rapamycin was prepared using amphiphilic block co-polymer micelles of poly(ethylene glycol)-b-poly(ε-caprolactone) (PEG–PCL)…”
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Probing the subcutaneous absorption of a PEGylated FUD peptide nanomedicine via in vivo fluorescence imaging by Zbyszynski, Pawel, Toraason, Inger, Repp, Lauren, Kwon, Glen S.

“…The Functional Upstream Domain (FUD) peptide is a potent inhibitor of fibronectin assembly and a therapeutic candidate for disorders linked with…”
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Bioreducible polyether-based pDNA ternary polyplexes: Balancing particle stability and transfection efficiency by Lai, Tsz Chung, Kataoka, Kazunori, Kwon, Glen S.

“…[Display omitted] ► Ternary polyionic complexes with surface covered with different ratios of PEG and P(EPE) polymers were prepared. ► Colloidal stability of…”
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Effect of Cholesterol on the Release of Amphotericin B from PEG-Phospholipid Micelles by Vakil, Ronak, S. Kwon, Glen

“…Micelles formed from PEG-DSPE solubilize high levels of the poorly water-soluble antifungal amphotericin B (AmB). AmB release from PEG-DSPE micelles is slow in…”
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Oligo(Lactic Acid)8-Docetaxel Prodrug-Loaded PEG-b-PLA Micelles for Prostate Cancer by Repp, Lauren, Unterberger, Christopher J., Ye, Zhengqing, Feltenberger, John B., Swanson, Steven M., Marker, Paul C., Kwon, Glen S.

“…Docetaxel (DTX) is among the most frequently prescribed chemotherapy drugs and has recently been shown to extend survival in advanced prostate cancer patients…”
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Block copolymer micelles as long-circulating drug vehicles by Kwon, Glen S., Kataoka, Kazunori

“…The development of block copolymer micelles as long-circulating drug vehicles is described. As well, a recent fundamental study of block copolymer micelles,…”
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Polymeric micelles for apoptosis-targeted optical imaging of cancer and intraoperative surgical guidance by Cho, Hyunah, Cho, Clifford S, Indig, Guilherme L, Lavasanifar, Afsaneh, Vakili, Mohammad Reza, Kwon, Glen S

“…In a two-step strategy, an intraperitoneal (IP) injection of poly(ethylene glycol)-block-poly(ε-caprolactone) (PEG-b-PCL) micelles containing paclitaxel (PTX),…”
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