Search Results - "Kwon, Deukwoo"

Phase 2 study of pembrolizumab and circulating biomarkers to predict anticancer response in advanced, unresectable hepatocellular carcinoma by Feun, Lynn G., Li, Ying‐Ying, Wu, Chunjing, Wangpaichitr, Medhi, Jones, Patricia D., Richman, Stephen P., Madrazo, Beatrice, Kwon, Deukwoo, Garcia‐Buitrago, Monica, Martin, Paul, Hosein, Peter J., Savaraj, Niramol

“…Background Checkpoint inhibitors have shown modest activity in patients with advanced hepatocellular carcinoma (HCC). Herein, the authors report a prospective…”
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Power calculation for detecting interaction effect in cross-sectional stepped-wedge cluster randomized trials: an important tool for disparity research by Yang, Chen, Berkalieva, Asem, Mazumdar, Madhu, Kwon, Deukwoo

“…The stepped-wedge cluster randomized trial (SW-CRT) design has become popular in healthcare research. It is an appealing alternative to traditional cluster…”
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Frequentist model averaging for analysis of dose-response in epidemiologic studies with complex exposure uncertainty by Kwon, Deukwoo, Simon, Steven L, Hoffman, F Owen, Pfeiffer, Ruth M

“…In epidemiologic studies, association estimates of an exposure with disease outcomes are often biased when the uncertainties of exposure are ignored…”
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Neutrophil-mediated fibroblast-tumor cell il-6/stat-3 signaling underlies the association between neutrophil-to-lymphocyte ratio dynamics and chemotherapy response in localized pancreatic cancer: A hybrid clinical-preclinical study by de Castro Silva, Iago, Bianchi, Anna, Deshpande, Nilesh U, Sharma, Prateek, Mehra, Siddharth, Garrido, Vanessa Tonin, Saigh, Shannon Jacqueline, England, Jonathan, Hosein, Peter Joel, Kwon, Deukwoo, Merchant, Nipun B, Datta, Jashodeep

“…Partial/complete pathologic response following neoadjuvant chemotherapy (NAC) in pancreatic cancer (PDAC) patients undergoing pancreatectomy is associated with…”
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Urolithin A, a Novel Natural Compound to Target PI3K/AKT/mTOR Pathway in Pancreatic Cancer by Totiger, Tulasigeri M, Srinivasan, Supriya, Jala, Venkatakrishna R, Lamichhane, Purushottam, Dosch, Austin R, Gaidarski, 3rd, Alexander A, Joshi, Chandrashekhar, Rangappa, Shobith, Castellanos, Jason, Vemula, Praveen Kumar, Chen, Xi, Kwon, Deukwoo, Kashikar, Nilesh, VanSaun, Michael, Merchant, Nipun B, Nagathihalli, Nagaraj S

“…Pancreatic ductal adenocarcinoma (PDAC) is an aggressive malignancy and is highly resistant to standard treatment regimens. Targeted therapies against , a…”
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Association of the prognostic model iSEND with PD-1/L1 monotherapy outcome in non-small-cell lung cancer by Park, Wungki, Mezquita, Laura, Okabe, Naoyuki, Chae, Young Kwang, Kwon, Deukwoo, Saravia, Diana, Auclin, Edouard, Planchard, David, Caramella, Caroline, Ferrara, Roberto, Agte, Sarita, Oh, Michael, Mudad, Raja, Jahanzeb, Mohammad, Suzuki, Hiroyuki, Besse, Benjamin, Lopes, Gilberto

“…Background Accessible biomarkers are needed for immunotherapy in advanced non-small-cell lung cancer (NSCLC). We previously described a multivariate risk…”
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Delays in definitive cervical cancer treatment: An analysis of disparities and overall survival impact by Ramey, Stephen J., Asher, David, Kwon, Deukwoo, Ahmed, Awad A., Wolfson, Aaron H., Yechieli, Raphael, Portelance, Lorraine

“…Delays in time to treatment initiation (TTI) with definitive radiation therapy (RT) or chemotherapy and RT (CRT) for cervical cancer could lead to poorer…”
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Solid cancer incidence among Chinese medical diagnostic x‐ray workers, 1950–1995: Estimation of radiation‐related risks by Sun, Zhijuan, Inskip, Peter D., Wang, Jixian, Kwon, Deukwoo, Zhao, Yongcheng, Zhang, Liangan, Wang, Qin, Fan, Saijun

“…The objective of this study was to estimate solid cancer risk attributable to long‐term, fractionated occupational exposure to low doses of ionizing radiation…”
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Predicting response to immunotherapy in non-small cell lung cancer- from bench to bedside by Montoya, Chris, Spieler, Benjamin, Welford, Scott M, Kwon, Deukwoo, Pra, Alan Dal, Lopes, Gilberto, Mihaylov, Ivaylo B

“…Immune checkpoint inhibitor (ICI) therapy is first-line treatment for many advanced non-small cell lung cancer (aNSCLC) patients. Predicting response could…”
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Cone-beam CT delta-radiomics to predict genitourinary toxicities and international prostate symptom of prostate cancer patients: a pilot study by Delgadillo, Rodrigo, Spieler, Benjamin O., Deana, Anthony M., Ford, John C., Kwon, Deukwoo, Yang, Fei, Studenski, Matthew T., Padgett, Kyle R., Abramowitz, Matthew C., Dal Pra, Alan, Stoyanova, Radka, Dogan, Nesrin

“…For prostate cancer (PCa) patients treated with definitive radiotherapy (RT), acute and late RT-related genitourinary (GU) toxicities adversely impact…”
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Association of Radiomics and Metabolic Tumor Volumes in Radiation Treatment of Glioblastoma Multiforme by Lopez, Christopher J., Ph.D, Nagornaya, Natalya, M.D, Parra, Nestor A., Ph.D, Kwon, Deukwoo, Ph.D, Ishkanian, Fazilat, M.D., Ph.D, Markoe, Arnold M., M.D., Sc.D, Maudsley, Andrew, Ph.D, Stoyanova, Radka, Ph.D

“…Abstract Purpose High-throughput extraction of imaging and metabolomomic quantitative features from MRI and MR Spectroscopy Imaging (MRSI) of Glioblastoma…”
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Thioredoxin-1 protects against androgen receptor-induced redox vulnerability in castration-resistant prostate cancer by Samaranayake, Govindi J., Troccoli, Clara I., Huynh, Mai, Lyles, Rolando D. Z., Kage, Karen, Win, Andrew, Lakshmanan, Vishalakshi, Kwon, Deukwoo, Ban, Yuguang, Chen, Steven Xi, Zarco, Enrique Rodriguez, Jorda, Merce, Burnstein, Kerry L., Rai, Priyamvada

“…Androgen deprivation (AD) therapy failure leads to terminal and incurable castration-resistant prostate cancer (CRPC). We show that the redox-protective…”
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Methods to account for uncertainties in exposure assessment in studies of environmental exposures by Wu, You, Hoffman, F Owen, Apostoaei, A Iulian, Kwon, Deukwoo, Thomas, Brian A, Glass, Racquel, Zablotska, Lydia B

“…Accurate exposure estimation in environmental epidemiological studies is crucial for health risk assessment. Failure to account for uncertainties in exposure…”
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Dosimetric Benefits and Practical Pitfalls of Daily Online Adaptive MRI-Guided Stereotactic Radiation Therapy for Pancreatic Cancer by El-Bared, Nancy, Portelance, Lorraine, Spieler, Benjamin O., Kwon, Deukwoo, Padgett, Kyle R., Brown, Karen M., Mellon, Eric A.

“…Magnetic resonance imaging guided (MRI-g) radiation therapy provides visualization of the target and organs at risk (OARs), allowing for daily online adaptive…”
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Predictive Value of Delta-Radiomics Texture Features in 0.35 Tesla Magnetic Resonance Setup Images Acquired During Stereotactic Ablative Radiotherapy of Pancreatic Cancer by Simpson, Garrett, Jin, William, Spieler, Benjamin, Portelance, Lorraine, Mellon, Eric, Kwon, Deukwoo, Ford, John C, Dogan, Nesrin

“…The purpose of this work is to explore delta-radiomics texture features for predicting response using setup images of pancreatic cancer patients treated with…”
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Efficacy and outcomes of ramucirumab and docetaxel in patients with metastatic non-small cell lung cancer after disease progression on immune checkpoint inhibitor therapy: Results of a monocentric, retrospective analysis by Kareff, Samuel A, Gawri, Kunal, Khan, Khadeja, Kwon, Deukwoo, Rodriguez, Estelamari, Lopes, Gilberto de Lima, Dawar, Richa

“…Current first-line standard therapy for metastatic non-small cell lung cancer without driver mutations involves chemotherapy and immunotherapy combination…”
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Systemic Reprogramming of Translation Efficiencies on Oxygen Stimulus by Ho, J.J. David, Wang, Miling, Audas, Timothy E., Kwon, Deukwoo, Carlsson, Steven K., Timpano, Sara, Evagelou, Sonia L., Brothers, Shaun, Gonzalgo, Mark L., Krieger, Jonathan R., Chen, Steven, Uniacke, James, Lee, Stephen

“…Protein concentrations evolve under greater evolutionary constraint than mRNA levels. Translation efficiency of mRNA represents the chief determinant of basal…”
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Accounting for Shared and Unshared Dosimetric Uncertainties in the Dose Response for Ultrasound-Detected Thyroid Nodules after Exposure to Radioactive Fallout by Land, Charles E., Kwon, Deukwoo, Hoffman, F. Owen, Moroz, Brian, Drozdovitch, Vladimir, Bouville, André, Beck, Harold, Luckyanov, Nicholas, Weinstock, Robert M., Simon, Steven L.

“…Dosimetic uncertainties, particularly those that are shared among subgroups of a study population, can bias, distort or reduce the slope or significance of a…”
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The mechanism of cancer drug addiction in ALK-positive T-Cell lymphoma by Rajan, Soumya S., Amin, Amit Dipak, Li, Lingxiao, Rolland, Delphine C., Li, Haiquan, Kwon, Deukwoo, Kweh, Mercedes F., Arumov, Artavazd, Roberts, Evan R., Yan, Aimin, Basrur, Venkatesha, Elenitoba-Johnson, Kojo S. J., Chen, Xi Steven, Puvvada, Soham D., Lussier, Yves A., Bilbao, Daniel, Lim, Megan S., Schatz, Jonathan H.

“…Rational new strategies are needed to treat tumors resistant to kinase inhibitors. Mechanistic studies of resistance provide fertile ground for development of…”
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Anterior or Posterior Prostate Cancer Tumor Nodule Location Predicts Likelihood of Certain Adverse Outcomes at Radical Prostatectomy by Hayee, Amin, Lugo, Isabella, Iakymenko, Oleksii A., Kwon, Deukwoo, Briski, Laurence M., Zhao, Wei, Nemov, Ivan, Punnen, Sanoj, Ritch, Chad R., Pollack, Alan, Jorda, Merce, Stoyanova, Radka, Parekh, Dipen J., Gonzalgo, Mark L., Kryvenko, Oleksandr N.

“…Context.— Effect of tumor nodule (TN) location in the prostate on adverse radical prostatectomy (RP) outcomes is not well studied in contemporary cohorts…”
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