Search Results - "Kwon, Daekee"
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Enhanced genome editing efficiency of CRISPR PLUS: Cas9 chimeric fusion proteins
Published in Scientific reports (10-08-2021)“…Efforts to improve CRISPR-Cas9 genome editing systems for lower off-target effects are mostly at the cost of its robust on-target efficiency. To enhance both…”
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Author Correction: Enhanced genome editing efficiency of CRISPR PLUS: Cas9 chimeric fusion proteins
Published in Scientific reports (10-09-2021)Get full text
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CD19 CAR-expressing iPSC-derived NK cells effectively enhance migration and cytotoxicity into glioblastoma by targeting to the pericytes in tumor microenvironment
Published in Biomedicine & pharmacotherapy (01-05-2024)“…In cancer immunotherapy, chimeric antigen receptors (CARs) targeting specific antigens have become a powerful tool for cell-based therapy. CAR-natural killer…”
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Accumulation of APP-CTF induces mitophagy dysfunction in the iNSCs model of Alzheimer’s disease
Published in Cell death discovery (10-01-2022)“…Mitochondrial dysfunction is associated with familial Alzheimer’s disease (fAD), and the accumulation of damaged mitochondria has been reported as an initial…”
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The Effect of Fetal Bovine Serum (FBS) on Efficacy of Cellular Reprogramming for Induced Pluripotent Stem Cell (iPSC) Generation
Published in Cell transplantation (01-06-2016)“…Induced pluripotent stem cells (iPSCs) are pivotal to the advancement of regenerative medicine. However, the low efficacy of iPSC generation and insufficient…”
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Reprogramming Enhancers in Somatic Cell Nuclear Transfer, iPSC Technology, and Direct Conversion
Published in Stem cell reviews (01-02-2017)“…Direct conversion of cell fate is a core technology for future regenerative medicine. However, the low reprogramming efficiency and low reproducibility are the…”
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Conditioned media from human umbilical cord blood-derived mesenchymal stem cells stimulate rejuvenation function in human skin
Published in Biochemistry and biophysics reports (01-12-2018)“…Developing treatments that inhibit skin aging is an important research project. Rejuvenation, which focuses on prevention of skin aging, is one of the major…”
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Generation of Genetically Stable Human Direct-Conversion-Derived Neural Stem Cells Using Quantity Control of Proto-oncogene Expression
Published in Molecular therapy. Nucleic acids (01-03-2019)“…As the human lifespan has increased due to developments in medical technology, the number of patients with neurological diseases has rapidly increased…”
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Nuclear-mitochondrial incompatibility in interorder rhesus monkey–cow embryos derived from somatic cell nuclear transfer
Published in Primates (01-10-2016)“…Monkey interorder somatic cell nuclear transfer (iSCNT) using enucleated cow oocytes yielded poor blastocysts development and contradictory results among…”
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hESC expansion and stemness are independent of connexin forty-three-mediated intercellular communication between hESCs and hASC feeder cells
Published in PloS one (26-07-2013)“…Human embryonic stem cells (hESCs) are a promising and powerful source of cells for applications in regenerative medicine, tissue engineering, cell-based…”
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Intrapancreatic ectopic splenic tissue found in a cloned miniature pig
Published in Journal of veterinary science (Suwŏn-si, Korea) (2015)“…Somatic cell nuclear transfer (SCNT) is a cost-effective technique for producing transgenic pigs. However, abnormalities in the cloned pigs might prevent use…”
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Establishment and characterization of human engineered cells stably expressing large extracellular matrix proteins
Published in Archives of pharmacal research (2014)“…Commercially available extracellular matrix (ECM) hydrogel-coated culture plates have been used to study the relationship between the ECM microenvironment and…”
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Genetically stable multi-gene edited iPSCs-derived NK cells for enhanced cancer immunotherapy
Published in Molecular Therapy: Oncology (19-12-2024)Get full text
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Abstract 1325: CD19 CAR-expressing iPSC-derived NK cells effectively enhance migration and cytotoxicity into glioblastoma by targeting to the pericytes in tumor microenvironment
Published in Cancer research (Chicago, Ill.) (22-03-2024)“…Abstract In cancer immunotherapy, targeting specific antigens with chimeric antigen receptors (CARs) has emerged as a potent tool for cell-based therapy. After…”
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Abstract 1330: Universal and potent chimeric antigen receptor-natural killer (upCAR-NK) cells for B-cell malignancy treatment
Published in Cancer research (Chicago, Ill.) (22-03-2024)“…Abstract Patient-specific CAR-T cells treatment is an innovative new drug that has shown excellent therapeutic effects against B cell blood cancer. However,…”
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Combinatorial Strategies for Long-term Control of HIV Infection
Published in AIDS reviews (23-12-2020)“…AIDS is a disease caused by a chronic infection of HIV. Recently, long-term control of HIV infection has been demonstrated through the bone marrow…”
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Generation of Human Neural Stem Cells by Direct Phenotypic Conversion
Published in Results and problems in cell differentiation (2018)“…Human neural stem cells (hNSC) are multipotent adult stem cells. Various studies are underway worldwide to identify new methods for treatment of neurological…”
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Establishment and characterization of human engineered cells stably expressing large extracellular matrix proteins
Published in Archives of pharmacal research (2014)“…Commercially available extracellular matrix (ECM) hydrogel-coated culture plates have been used to study the relationship between the ECM microenvironment and…”
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Optimization of Artificial Activation in Porcine Embryos Using Short-Term Treatment of 6-DMAP and Demecolcine
Published in Biology of reproduction (01-07-2009)Get full text
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