Search Results - "Kwok, Seung‑Ki"
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1
The underestimated significance of nonproliferative lupus nephritis
Published in The Korean journal of internal medicine (01-09-2023)“…KCI Citation Count: 0…”
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2
Interleukin-10 produced by myeloid-derived suppressor cells is critical for the induction of Tregs and attenuation of rheumatoid inflammation in mice
Published in Scientific reports (28-02-2018)“…Myeloid-derived suppressor cells (MDSCs) are heterogenous populations of immature myeloid progenitor cells with immunoregulatory function. MDSCs play critical…”
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3
Recent Advances in Our Understanding of the Link between the Intestinal Microbiota and Systemic Lupus Erythematosus
Published in International journal of molecular sciences (30-09-2019)“…Systemic lupus erythematosus (SLE) is an autoimmune disease featuring enhanced expression of type I interferon (IFN) and autoantibody production triggering…”
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4
Myeloid‐Derived Suppressor Cells Induce the Expansion of Regulatory B Cells and Ameliorate Autoimmunity in the Sanroque Mouse Model of Systemic Lupus Erythematosus
Published in Arthritis & rheumatology (Hoboken, N.J.) (01-11-2016)“…Objective This study was undertaken to assess the effect of myeloid‐derived suppressor cells (MDSCs) on various B cell subsets, including regulatory B cells,…”
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5
JAK-1 Inhibition Suppresses Interferon-Induced BAFF Production in Human Salivary Gland: Potential Therapeutic Strategy for Primary Sjögren's Syndrome
Published in Arthritis & rheumatology (Hoboken, N.J.) (01-12-2018)“…To examine whether a JAK inhibitor regulates functional responses of human salivary gland epithelial cells (SGECs) and disease parameters in an animal model of…”
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Mesenchymal Stem/Stromal Cell-Based Therapies in Systemic Rheumatic Disease: From Challenges to New Approaches for Overcoming Restrictions
Published in International journal of molecular sciences (15-06-2023)“…Systemic rheumatic diseases, such as rheumatoid arthritis, systemic lupus erythematosus, and systemic sclerosis, are chronic autoimmune diseases affecting…”
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Short-chain fatty acid butyrate induces IL-10-producing B cells by regulating circadian-clock-related genes to ameliorate Sjögren's syndrome
Published in Journal of autoimmunity (01-05-2021)“…Sjögren's syndrome (SS) is an autoimmune disease caused by inflammation of the exocrine gland. The pathological hallmark of SS is the infiltration of…”
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Metformin Augments Anti-Inflammatory and Chondroprotective Properties of Mesenchymal Stem Cells in Experimental Osteoarthritis
Published in The Journal of immunology (1950) (01-07-2019)“…Mesenchymal stem cells (MSCs) can protect against cartilage breakdown in osteoarthritis (OA) via their immunomodulatory capacities. However, the optimization…”
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B Cell–Specific Deletion of CR6‐Interacting Factor 1 Drives Lupus‐like Autoimmunity by Activation of Interleukin‐17, Interleukin‐6, and Pathogenic Follicular Helper T Cells in a Mouse Model
Published in Arthritis & rheumatology (Hoboken, N.J.) (01-07-2022)“…Objective CR6‐interacting factor 1 (CRIF1) is a nuclear transcriptional regulator and a mitochondrial inner membrane protein; however, its functions in B…”
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Predictors for future development of systemic lupus erythematosus in Korean Sjögren’s syndrome patients
Published in Lupus (01-10-2023)“…Objective This study determined the impact of demographic factors, clinical manifestations, disease activity, and serological tests at baseline on future SLE…”
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11
Longitudinal analysis of symptom-based clustering in patients with primary Sjogren's syndrome: a prospective cohort study with a 5-year follow-up period
Published in Journal of translational medicine (19-09-2021)“…Sjogren's syndrome (SS) is a heterogenous disease with various phenotypes. We aimed to provide a relevant subclassification based on symptom-based clustering…”
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12
Alcohol consumption as a predictor of the progression of spinal structural damage in axial spondyloarthritis: data from the Catholic Axial Spondyloarthritis COhort (CASCO)
Published in Arthritis research & therapy (14-08-2019)“…The purpose of the present study was to demonstrate whether alcohol consumption could predict spinal structural damage in axial spondyloarthritis (axSpA) in a…”
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13
Male patients with primary Sjögren's syndrome: A distinct clinical subgroup?
Published in International journal of rheumatic diseases (01-10-2020)“…Aim Because the clinical and immunologic phenotypes of male primary Sjögren's syndrome (pSS) patients have not been fully elucidated, we aimed to investigate…”
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14
Epigenetic analysis in rheumatoid arthritis synoviocytes
Published in Experimental & molecular medicine (22-02-2019)“…Rheumatoid arthritis (RA) is a complex chronic systematic disease with progressive destruction of the joints by invasive synoviocytes. To characterize the key…”
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Lactobacillus acidophilus Supplementation Exerts a Synergistic Effect on Tacrolimus Efficacy by Modulating Th17/Treg Balance in Lupus-Prone Mice via the SIGNR3 Pathway
Published in Frontiers in immunology (10-12-2021)“…Tacrolimus (Tac) is an immunosuppressant used in the treatment of systemic lupus erythematosus (SLE); however, it induces T cell subset imbalances by reducing…”
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Baricitinib Attenuates Autoimmune Phenotype and Podocyte Injury in a Murine Model of Systemic Lupus Erythematosus
Published in Frontiers in immunology (23-08-2021)“…Baricitinib, a selective inhibitor for janus kinase (JAK) 1 and JAK2, is approved for use in rheumatoid arthritis. Systemic lupus erythematosus (SLE) is…”
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Myeloid-derived suppressor cells therapy enhance immunoregulatory properties in acute graft versus host disease with combination of regulatory T cells
Published in Journal of translational medicine (14-12-2020)“…Myeloid-derived suppressor cells (MDSCs) play a critical role in modulating the immune response and promoting immune tolerance in models of autoimmunity and…”
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Adipose tissue-derived mesenchymal stem cells induce expansion of interleukin-10-producing regulatory B cells and ameliorate autoimmunity in a murine model of systemic lupus erythematosus
Published in Cell transplantation (01-11-2015)“…Mesenchymal stem cells (MSCs) are multipotent cells characterized by immunomodulatory properties and are therefore considered a promising tool for the…”
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IL-1-IL-17 Signaling Axis Contributes to Fibrosis and Inflammation in Two Different Murine Models of Systemic Sclerosis
Published in Frontiers in immunology (10-07-2018)“…Systemic sclerosis (SSc) is a progressive fibrotic disease that affects the skin and internal organs. Despite evidence implicating increased interleukin-17…”
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Ultrasonographic characteristics of major salivary glands in anti-centromere antibody-positive primary Sjögren's syndrome
Published in PloS one (03-11-2021)“…To investigate salivary gland ultrasonography (SGUS) findings in primary Sjögren's syndrome (pSS) patients positive for the anti-centromere antibody (ACA) and…”
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