Search Results - "Kwok, Jessica CF"

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  1. 1

    Selective rab11 transport and the intrinsic regenerative ability of CNS axons by Koseki, Hiroaki, Donegá, Matteo, Lam, Brian Yh, Petrova, Veselina, van Erp, Susan, Yeo, Giles Sh, Kwok, Jessica Cf, Ffrench-Constant, Charles, Eva, Richard, Fawcett, James W

    Published in eLife (08-08-2017)
    “…Neurons lose intrinsic axon regenerative ability with maturation, but the mechanism remains unclear. Using an in-vitro laser axotomy model, we show a…”
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    Journal Article
  2. 2

    Chondroitin sulfates in the developing rat hindbrain confine commissural projections of vestibular nuclear neurons by Kwok, Jessica C F, Yuen, Ying-Lai, Lau, Wai-Kit, Zhang, Fu-Xing, Fawcett, James W, Chan, Ying-Shing, Shum, Daisy K Y

    Published in Neural development (03-02-2012)
    “…Establishing correct neuronal circuitry is crucial to proper function of the vertebrate nervous system. The abundance of chondroitin sulfate (CS) proteoglycans…”
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  3. 3

    New Model of Ventral Spinal Cord Lesion Induced by Balloon Compression in Rats by Krupa, Petr, Stepankova, Katerina, Kwok, Jessica Cf, Fawcett, James W, Cimermanova, Veronika, Jendelova, Pavla, Machova Urdzikova, Lucia

    Published in Biomedicines (05-11-2020)
    “…Despite the variety of experimental models of spinal cord injury (SCI) currently used, the model of the ventral compression cord injury, which is commonly seen…”
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  4. 4

    Casting a Wide Net: Role of Perineuronal Nets in Neural Plasticity by Sorg, Barbara A, Berretta, Sabina, Blacktop, Jordan M, Fawcett, James W, Kitagawa, Hiroshi, Kwok, Jessica C F, Miquel, Marta

    Published in The Journal of neuroscience (09-11-2016)
    “…Perineuronal nets (PNNs) are unique extracellular matrix structures that wrap around certain neurons in the CNS during development and control plasticity in…”
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  5. 5

    Role of extracellular factors in axon regeneration in the CNS: implications for therapy by Gervasi, Noreen M, Kwok, Jessica Cf, Fawcett, James W

    Published in Regenerative medicine (01-11-2008)
    “…The glial scar that forms after an injury to the CNS contains molecules that are inhibitory to axon growth. Understanding of the mechanisms of inhibition has…”
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  6. 6

    Glycosaminoglycans in extracellular matrix organisation: are concepts from soft matter physics key to understanding the formation of perineuronal nets? by Richter, Ralf P, Baranova, Natalia S, Day, Anthony J, Kwok, Jessica CF

    Published in Current opinion in structural biology (01-06-2018)
    “…•Glycosaminoglycan physical properties contribute to distinct biochemical functions.•Hyaluronan is a unique scaffolding material, enabling matrix…”
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  7. 7

    The potential of memory enhancement through modulation of perineuronal nets by Duncan, James A., Foster, Richard, Kwok, Jessica C.F.

    Published in British journal of pharmacology (01-09-2019)
    “…With an increasingly aging global population, the incidence of neurological diseases such as dementia is set to increase to unmanageable levels, yet there are…”
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  8. 8

    Animals lacking link protein have attenuated perineuronal nets and persistent plasticity by Carulli, Daniela, Pizzorusso, Tommaso, Kwok, Jessica C. F., Putignano, Elena, Poli, Andrea, Forostyak, Serhiy, Andrews, Melissa R., Deepa, Sathyaseelan S., Glant, Tibor T., Fawcett, James W.

    Published in Brain (London, England : 1878) (01-08-2010)
    “…Chondroitin sulphate proteoglycans in the extracellular matrix restrict plasticity in the adult central nervous system and their digestion with chondroitinase…”
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  9. 9

    In vitro modeling of perineuronal nets: hyaluronan synthase and link protein are necessary for their formation and integrity by Kwok, Jessica C.F, Carulli, Daniela, Fawcett, James W

    Published in Journal of neurochemistry (01-09-2010)
    “…J. Neurochem. (2010) 114, 1447-1459. We have previously shown that all perineuronal nets (PNNs) bearing neurons express a hyaluronan synthase (HAS), a link…”
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    The chemorepulsive axon guidance protein semaphorin3A is a constituent of perineuronal nets in the adult rodent brain by Vo, Tam, Carulli, Daniela, Ehlert, Erich M.E., Kwok, Jessica C.F., Dick, Gunnar, Mecollari, Vasil, Moloney, Elizabeth B., Neufeld, Gera, de Winter, Fred, Fawcett, James W., Verhaagen, Joost

    Published in Molecular and cellular neuroscience (01-09-2013)
    “…In the adult rodent brain, subsets of neurons are surrounded by densely organised extracellular matrix called perineuronal nets (PNNs). PNNs consist of…”
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  13. 13
  14. 14

    Distribution and synthesis of extracellular matrix proteoglycans, hyaluronan, link proteins and tenascin-R in the rat spinal cord by Galtrey, Clare M., Kwok, Jessica C. F., Carulli, Daniela, Rhodes, Kate E., Fawcett, James W.

    Published in The European journal of neuroscience (01-03-2008)
    “…Perineuronal nets (PNNs) are dense extracellular matrix (ECM) structures that form around many neuronal cell bodies and dendrites late in development. They…”
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  15. 15

    Effects of digesting chondroitin sulfate proteoglycans on plasticity in cat primary visual cortex by Vorobyov, Vasily, Kwok, Jessica C F, Fawcett, James W, Sengpiel, Frank

    Published in The Journal of neuroscience (02-01-2013)
    “…Monocular deprivation (MD) during a critical period of postnatal development produces significant changes in the anatomy and physiology of the visual cortex,…”
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  16. 16

    Proteoglycans in the central nervous system: plasticity, regeneration and their stimulation with chondroitinase ABC by Kwok, Jessica C F, Afshari, Fardad, García-Alías, Guillermo, Fawcett, James W

    “…After injury to the mammalian central nervous system (CNS), neurons are not able to regenerate their axons and recovery is limited by restricted plasticity…”
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  17. 17

    Full length talin stimulates integrin activation and axon regeneration by Tan, Chin Lik, Kwok, Jessica C.F., Heller, Janosch P.D., Zhao, Rongrong, Eva, Richard, Fawcett, James W.

    Published in Molecular and cellular neuroscience (01-09-2015)
    “…Integrin function is regulated by activation involving conformational changes that modulate ligand-binding affinity and downstream signaling. Activation is…”
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