Search Results - "Kwiatkowski, D. P"

Mapping a 50-spin-qubit network through correlated sensing by van de Stolpe, G. L., Kwiatkowski, D. P., Bradley, C. E., Randall, J., Abobeih, M. H., Breitweiser, S. A., Bassett, L. C., Markham, M., Twitchen, D. J., Taminiau, T. H.

“…Spins associated to optically accessible solid-state defects have emerged as a versatile platform for exploring quantum simulation, quantum sensing and quantum…”
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Genetic association study for RSV bronchiolitis in infancy at the 5q31 cytokine cluster by Forton, J T, Rowlands, K, Rockett, K, Hanchard, N, Herbert, M, Kwiatkowski, D P, Hull, J

“…The pathophysiological basis of severe respiratory syncytial virus (RSV) bronchiolitis in infancy is poorly understood and has hindered vaccine development…”
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A Comparison of Case‐Control and Family‐Based Association Methods: The Example of Sickle‐Cell and Malaria by Ackerman, H., Usen, S., Jallow, M., Sisay‐Joof, F., Pinder, M., Kwiatkowski, D. P.

“…Summary There has been much debate about the relative merits of population‐ and family‐based strategies for testing genetic association, yet there is little…”
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Increased in vivo transcription of an IL-8 haplotype associated with respiratory syncytial virus disease-susceptibility by Hacking, D, Knight, J C, Rockett, K, Brown, H, Frampton, J, Kwiatkowski, D P, Hull, J, Udalova, I A

“…Interleukin-8 (IL-8) has been implicated in the pathogenesis of RSV-induced bronchiolitis. Previously, we have described an association between bronchiolitis…”
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Genetic variation at the TNF locus and the risk of severe sequelae of ocular Chlamydia trachomatis infection in Gambians by Natividad, A, Hanchard, N, Holland, M J, Mahdi, O S M, Diakite, M, Rockett, K, Jallow, O, Joof, H M, Kwiatkowski, D P, Mabey, D C W, Bailey, R L

“…Tumor necrosis factor (TNF) is thought to be a key mediator of the inflammatory and fibrotic response to Chlamydia trachomatis (Ct) infection. A large…”
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Haplotypic relationship between SNP and microsatellite markers at the NOS2A locus in two populations by BURGNER, D, ROCKETT, K, ACKERMAN, H, HULL, J, USEN, S, PINDER, M, KWIATKOWSKI, D. P

“…The density of genetic markers required for successful association mapping of complex diseases depends on linkage disequilibrium (LD) between non-functional…”
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How Malaria Has Affected the Human Genome and What Human Genetics Can Teach Us about Malaria by Kwiatkowski, Dominic P.

“…Malaria is a major killer of children worldwide and the strongest known force for evolutionary selection in the recent history of the human genome. The past…”
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Haplotypic diversity in human CEACAM genes: effects on susceptibility to meningococcal disease by Callaghan, M J, Rockett, K, Banner, C, Haralambous, E, Betts, H, Faust, S, Maiden, M C J, Kroll, J S, Levin, M, Kwiatkowski, D P, Pollard, A J

“…Adhesion between the opacity-associated adhesin (Opa) proteins of Neisseria meningitidis and human carcino-embryonic antigen cell adhesion molecule (CEACAM)…”
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Risk of trachomatous scarring and trichiasis in Gambians varies with SNP haplotypes at the interferon-gamma and interleukin-10 loci by Natividad, A, Wilson, J, Koch, O, Holland, M J, Rockett, K, Faal, N, Jallow, O, Joof, H M, Burton, M J, Alexander, N D E, Kwiatkowski, D P, Mabey, D C W, Bailey, R L

“…Experimental evidence implicates interferon gamma (IFNgamma) in protection from and resolution of chlamydial infection. Conversely, interleukin 10 (IL10) is…”
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Complex haplotypic structure of the central MHC region flanking TNF in a West African population by ACKERMAN, H. C, RIBAS, G, JALLOW, M, MOTT, R, NEVILLE, M, SISAY-JOOF, F, PINDER, M, CAMPBELL, R. D, KWIATKOWSKI, D. P

“…TNF polymorphisms have been associated with susceptibility to malaria and other infectious and inflammatory conditions. We investigated a sample of 150 West…”
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Perturbation Analysis: A Simple Method for Filtering SNPs with Erroneous Genotyping in Genome‐Wide Association Studies by Teo, Y. Y., Small, K. S., Clark, T. G., Kwiatkowski, D. P.

“…Summary We introduce a simple and yet scientifically objective criterion for identifying SNPs with genotyping errors due to poor clustering. This yields a…”
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Variation in human genes encoding adhesion and proinflammatory molecules are associated with severe malaria in the Vietnamese by Dunstan, S J, Rockett, K A, Quyen, N T N, Teo, Y Y, Thai, C Q, Hang, N T, Jeffreys, A, Clark, T G, Small, K S, Simmons, C P, Day, N, O'Riordan, S E, Kwiatkowski, D P, Farrar, J, Phu, N H, Hien, T T

“…The genetic basis for susceptibility to malaria has been studied widely in African populations but less is known of the contribution of specific genetic…”
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Allele-specific repression of lymphotoxin-α by activated B cell factor-1 by Knight, Julian C, Keating, Brendan J, Kwiatkowski, Dominic P

“…Genetic variation at the human LTA locus, encoding lymphotoxin-α, is associated with susceptibility to myocardial infarction, asthma and other diseases. By…”
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Variation in the ICAM1 gene is not associated with severe malaria phenotypes by Fry, A E, Auburn, S, Diakite, M, Green, A, Richardson, A, Wilson, J, Jallow, M, Sisay-Joof, F, Pinder, M, Griffiths, M J, Peshu, N, Williams, T N, Marsh, K, Molyneux, M E, Taylor, T E, Rockett, K A, Kwiatkowski, D P

“…Evidence from autopsy and in vitro binding studies suggests that adhesion of erythrocytes infected with Plasmodium falciparum to the human host intercellular…”
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Genomewide Analysis of the Host Response to Malaria in Kenyan Children by Griffiths, Michael J., Shafi, Mohammed J., Popper, Stephen J., Hemingway, Cheryl A., Kortok, Moses M., Wathen, Andrew, Rockett, Kirk A., Mott, Richard, Levin, Michael, Newton, Charles R., Marsh, Kevin, Relman, David A., Kwiatkowski, Dominic P.

“…Malaria is a global problem, and there is a critical need for further understanding of the disease process. When malarial parasites invade and develop within…”
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Interferon regulatory factor-1 polymorphisms are associated with the control of Plasmodium falciparum infection by Mangano, V D, Luoni, G, Rockett, K A, Sirima, B S, Konaté, A, Forton, J, Clark, T G, Bancone, G, Akha, E S, Kwiatkowski, D P, Modiano, D

“…We describe the haplotypic structure of the interferon regulatory factor-1 (IRF-1) locus in two West African ethnic groups, Fulani and Mossi, that differ in…”
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Severe malaria in Gambian children is not due to lack of previous exposure to malaria by ERUNKULU, O. A., HILL, A V. S., KWIATKOWSKI, D. P., TODD, J. E., IQBAL, J., BERZINS, K., RILEY, E. M., GREENWOOD, B. M.

“…SUMMARY The reasons why only a small proportion of African children infected with Plasmodium falciparum develop severe or fatal malaria are not known. One…”
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Stimulators of tumour necrosis factor production released by damaged erythrocytes by Bate, C A, Kwiatkowski, D P

“…We sought to characterize factors released by sonicated human erythrocytes that stimulate peripheral blood mononuclear cells (PBMC) to release tumour necrosis…”
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Response of the Splenic Dendritic Cell Population to Malaria Infection by LEJSEWJTZ, Andrew L, ROCKETT, Kirk A, GUMEDE, Bonginkosi, JONES, Margaret, URBAN, Britta, KWIATKOWSKI, Dominic P

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Mapping a 50-spin-qubit network through correlated sensing by van de Stolpe, G. L, Kwiatkowski, D. P, Bradley, C. E, Randall, J, Abobeih, M. H, Breitweiser, S. A, Bassett, L. C, Markham, M, Twitchen, D. J, Taminiau, T. H

“…Nat Commun 15, 2006 (2024) Spins associated to optically accessible solid-state defects have emerged as a versatile platform for exploring quantum simulation,…”
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