Search Results - "Kweon, M N"

Immunosuppressive properties of human amniotic membrane for mixed lymphocyte reaction by UETA, M., KWEON, M.‐N., SANO, Y., SOTOZONO, C., YAMADA, J., KOIZUMI, N., KIYONO, H., KINOSHITA, S.

“…SUMMARY The combination of allograft limbal transplantation (ALT) and amniotic membrane transplantation (AMT) has been applied in the treatment of severe…”
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Gut commensal Bacteroides acidifaciens prevents obesity and improves insulin sensitivity in mice by Yang, J-Y, Lee, Y-S, Kim, Y., Lee, S-H, Ryu, S., Fukuda, S., Hase, K., Yang, C-S, Lim, H.S., Kim, M-S, Kim, H-M, Ahn, S-H, Kwon, B-E, Ko, H-J, Kweon, M-N

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Alternate Mucosal Immune System: Organized Peyer's Patches Are Not Required for IgA Responses in the Gastrointestinal Tract by Yamamoto, Masafumi, Rennert, Paul, McGhee, Jerry R, Kweon, Mi-Na, Yamamoto, Shingo, Dohi, Taeko, Otake, Shigeo, Bluethmann, Horst, Fujihashi, Kohtaro, Kiyono, Hiroshi

“…The progeny of mice treated with lymphotoxin (LT)-beta receptor (LTbetaR) and Ig (LTbetaR-Ig) lack Peyer's patches but not mesenteric lymph nodes (MLN). In…”
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Enterotoxin Adjuvants Have Direct Effects on T Cells and Antigen-Presenting Cells That Result in Either Interleukin-4-Dependent or -Independent Immune Responses by Yamamoto, Masafumi, Kiyono, Hiroshi, Kweon, Mi-Na, Yamamoto, Shingo, Fujihashi, Kohtaro, Kurazono, Hisao, Imaoka, Koichi, Bluethmann, Horst, Takahashi, Ichiro, Takeda, Yoshifumi, Azuma, Miyuki, McGhee, Jerry R.

“…In an in vitro study, Escherichia coli heat-labile toxin (LT) was shown to directly affect activated CD4+ T cells and support interleukin (IL)-5 production in…”
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iNKT cells prevent obesity-induced hepatic steatosis in mice in a C-C chemokine receptor 7-dependent manner by Kim, H M, Lee, B R, Lee, E S, Kwon, M H, Huh, J H, Kwon, B-E, Park, E-K, Chang, S-Y, Kweon, M-N, Kim, P-H, Ko, H-J, Chung, C H

“…Non-alcoholic fatty liver disease and non-alcoholic steatohepatitis are characterized by an increase in hepatic triglyceride content with infiltration of…”
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Partial IgA-deficiency with increased Th2-type cytokines in TGF-beta 1 knockout mice by van Ginkel, F W, Wahl, S M, Kearney, J F, Kweon, M N, Fujihashi, K, Burrows, P D, Kiyono, H, McGhee, J R

“…Though it has been shown that TGF-beta 1 directs B cells to switch to IgA in vitro, no studies have assessed TGF-beta 1 effects on mucosal vs systemic immunity…”
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The mucosal immune system: from specialized immune defense to inflammation and allergy by Kiyono, H, Kweon, M N, Hiroi, T, Takahashi, I

“…The mucosal immune system is a first line of defense against foreign antigens, including microbial and dietary antigens. Under normal circumstances, the…”
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Development of antigen induced colitis in SCID mice reconstituted with spleen derived memory type CD4+ CD45RB+ T cells by Kweon, M-N, Takahashi, I, Yamamoto, M, Jang, M H, Suenobu, N, Kiyono, H

“…Background and aims: Enteric bacterial and/or food antigens may be crucial in the development of colitis but little is known of the exact mechanism of antigen…”
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Direct Effects on Antigen-Presenting Cells and T Lymphocytes Explain the Adjuvanticity of a Nontoxic Cholera Toxin Mutant by Yamamoto, Masafumi, Kiyono, Hiroshi, Yamamoto, Shingo, Batanero, Eva, Kweon, Mi-Na, Otake, Shigeo, Azuma, Miyuki, Takeda, Yoshifumi, McGhee, Jerry R

“…The present study has elucidated two distinct mechanisms that may explain how a mutant of cholera toxin (mCT), E112K, retains adjuvant effects though it lacks…”
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Intestinal Villous M Cells: An Antigen Entry Site in the Mucosal Epithelium by Jang, Myoung Ho, Kweon, Mi-Na, Iwatani, Koichi, Yamamoto, Masafumi, Terahara, Kazutaka, Sasakawa, Chihiro, Suzuki, Toshihiko, Nochi, Tomonori, Yokota, Yoshifumi, Rennert, Paul D., Hiroi, Takachika, Tamagawa, Hiroshi, Iijima, Hideki, Kunisawa, Jun, Yuki, Yoshikazu, Kiyono, Hiroshi, Curtiss, Roy

“…M cells located in the follicle-associated epithelium of Peyer's patches (PP) are shown to be the principal sites for the sampling of gut luminal antigens…”
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Comparison of nasal and oral tolerance for the prevention of collagen induced murine arthritis by Higuchi, K, Kweon, M N, Fujihashi, K, McGhee, J R, Kiyono, H

“…Administration of bovine type II collagen (CII) or of its peptide either orally or nasally has been reported to suppress the development of collagen induced…”
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Mucosally Induced Systemic T Cell Unresponsiveness to Ovalbumin Requires CD40 Ligand-CD40 Interactions by Kweon, Mi-Na, Fujihashi, Kohtaro, Wakatsuki, Yoshio, Koga, Toshiya, Yamamoto, Masafumi, McGhee, Jerry R, Kiyono, Hiroshi

“…CD40 ligand (CD40L) gene-disrupted (CD40L-/-) mice were employed to examine the role of costimulatory signals via CD40L-CD40 interactions in mucosally induced…”
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Nasal administration of cholera toxin (CT) suppresses clinical signs of experimental autoimmune encephalomyelitis (EAE) by Yura, Mamoru, Takahashi, Ichiro, Terawaki, Seigo, Hiroi, Takachika, Kweon, Mi-Na, Yuki, Yoshikazu, Kiyono, Hiroshi

“…Cholera toxin (CT), a major enterotoxin produced by Vibrio cholerae, elicits mucosal adjuvant activities by inducing antigen-specific CD4 + T cells secreting T…”
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Systemically derived large intestinal CD4(+) Th2 cells play a central role in STAT6-mediated allergic diarrhea by Kweon, M N, Yamamoto, M, Kajiki, M, Takahashi, I, Kiyono, H

“…Systemically primed BALB/c mice developed severe diarrhea after repeated oral administration of ovalbumin (OVA). Histological analysis demonstrated that…”
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A non-glycosylated form of pulmonary surfactant protein A appears in rat amniotic fluid by Sakai, K, Kohri, T, Kweon, MN, Kishino, Y

“…Surfactant protein A (SP-A) is a family of glycoproteins that have a triplet with 26, 32 and 36 kDa under reducing conditions in rat lung. We wanted to…”
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The mechanisms of oral tolerance by Yamamoto, M, Kweon, M N, Kiyono, H

“…Oral or nasal administration of a single high dose or repeated mucosal delivery of low doses of proteins have been shown to induce systemic unresponsiveness in…”
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Gut commensal Bacteroides acidifaciens prevents obesity and improves insulin sensitivity in mice by Yang, J-Y, Lee, Y-S, Kim, Y, Lee, S-H, Ryu, S, Fukuda, S, Hase, K, Yang, C-S, Lim, H S, Kim, M-S, Kim, H-M, Ahn, S-H, Kwon, B-E, Ko, H-J, Kweon, M-N

“…In humans, the composition of gut commensal bacteria is closely correlated with obesity. The bacteria modulate metabolites and influence host immunity. In this…”
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gamma/delta T cell-deficient mice have impaired mucosal immunoglobulin A responses by Fujihashi, K, McGhee, J R, Kweon, M N, Cooper, M D, Tonegawa, S, Takahashi, I, Hiroi, T, Mestecky, J, Kiyono, H

“…Mucosal tissues of mice are enriched in T cells that express the gamma/delta T cell receptor. Since the function of these cells remains unclear, we have…”
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A Nontoxic Chimeric Enterotoxin Adjuvant Induces Protective Immunity in Both Mucosal and Systemic Compartments with Reduced IgE Antibodies by Kweon, Mi-Na, Yamamoto, Masafumi, Watanabe, Fumiko, Tamura, Shinichi, van Ginkel, Frederik W., Miyauchi, Akira, Takagi, Hiroaki, Takeda, Yoshifumi, Hamabata, Takashi, Fujihashi, Kohtaro, McGhee, Jerry R., Kiyono, Hiroshi

“…A novel nontoxic form of chimeric mucosal adjuvant that combines the A subunit of mutant cholera toxin E112K with the pentameric B subunit of heat-labile…”
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Effects of pulmonary surfactant and surfactant protein A on phagocytosis of fractionated alveolar macrophages: relationship to starvation by Sakai, K, Kweon, M N, Kohri, T, Kishino, Y

“…Pulmonary surfactant isolated from bronchoalveolar lavage fluid of rat lung contained a high content of surfactant protein A (SP-A) in starved for 2 days…”
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