Search Results - "Kwee, Jolie K"

Design, Synthesis, and Pharmacological Evaluation of Novel N‑Acylhydrazone Derivatives as Potent Histone Deacetylase 6/8 Dual Inhibitors by Rodrigues, Daniel A, Ferreira-Silva, Guilherme À, Ferreira, Ana C. S, Fernandes, Renan A, Kwee, Jolie K, Sant’Anna, Carlos M. R, Ionta, Marisa, Fraga, Carlos A. M

“…This manuscript describes a novel class of N-acylhydrazone (NAH) derivatives that act as histone deacetylase (HDAC) 6/8 dual inhibitors and were designed from…”
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Ação de Sais de Cobre sobre a Xantina Desidrogenase na Carcinogênese Hepática de Ratas by Affonso, Ottilia R., Souza, Arthurs. R., Kwee, Jolie K., Asch, Karen H., Mitidieri, Emílio

“…Os autores estudaram a inibição da atividade de xantina desidrogenase (XD) do soro de ratas pelo acetado de cobre (AcCu). Verificaram também a relação entre a…”
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Contrasting features of MDR phenotype in leukemias by using two fluorochromes: Implications for clinical practice by Vasconcelos, Flavia C, Cavalcanti, Geraldo B, Silva, Karina L, de Meis, Ernesto, Kwee, Jolie K, Rumjanek, Vivian M, Maia, Raquel C

“…Abstract The expression and activity of P-glycoprotein (Pgp) and multidrug resistance-associated protein (MRP1) were analyzed in 178 leukemia samples…”
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CPT-11-induced cell death in leukemic cells is not affected by the MDR phenotype by Silva, Karina L, Vasconcelos, Flavia C, Marques-Santos, Luis Fernando, Kwee, Jolie K, Maia, Raquel C

“…CPT-11 is a topoisomerase I (Topo I) inhibitor which was initially described as active in multi-drug resistance (MDR) tumors. The MDR phenomenon is…”
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Leishmania amazonensis infection is reduced in macrophages treated with guanine ribonucleosides by Giorgio, Selma, Barão, Sandra C, Augusto, Ohara, Kwee, Jolie K

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Cell proliferation induced by 8-oxoguanosine and 8-methylguanosine, two adducts produced by free radical attack on ribonucleosides and RNA by Kwee, Jolie K, Armelin, Mari S, Stefani, Hélio A, Augusto, Ohara

“…The ability of C8-substituted guanine (Gua) ribonucleosides to induce B cell proliferation has been well documented in the literature. These compounds are…”
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High Catalase Activity: Another Possible Pathway for Imatinib-Resistant CML Patients by Luque, Diogo G., Ferreira, Ana Carolina S., Vasconcelos, Flavia C., Maia, Raquel C., Kwee, Jolie K.

“…Imatinib (imatinib mesylate: Novartis Pharmaceuticals, Basel, Switzerland) is a well-known selective inhibitor of BCR-ABL tyrosine kinase activity, a hallmark…”
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