Search Results - "Kwart, Ariel"

A clinically relevant in vivo zebrafish model of human multiple myeloma to study preclinical therapeutic efficacy by Lin, Jianhong, Zhang, Weihong, Zhao, Jian-Jun, Kwart, Ariel H., Yang, Chun, Ma, Dongdong, Ren, Xiubao, Tai, Yu-Tzu, Anderson, Kenneth C., Handin, Robert I., Munshi, Nikhil C.

“…Patient-derived multiple myeloma (MM) cells are difficult to establish in culture or propagate in vivo in murine model. Here, we describe a zebrafish xenograft…”
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Cisplatin-Mediated Upregulation of APE2 Binding to MYH9 Provokes Mitochondrial Fragmentation and Acute Kidney Injury by Hu, Yi, Yang, Chun, Amorim, Tania, Maqbool, Mohsin, Lin, Jenny, Li, Chen, Fang, Chuanfeng, Xue, Li, Kwart, Ariel, Fang, Hua, Yin, Mei, Janocha, Allison J, Tsuchimoto, Daisuke, Nakabeppu, Yusaku, Jiang, Xiaofeng, Mejia-Garcia, Alex, Anwer, Faiz, Khouri, Jack, Qi, Xin, Zheng, Qing Y, Yu, Jennifer S, Yan, Shan, LaFramboise, Thomas, Anderson, Kenneth C, Herlitz, Leal C, Munshi, Nikhil C, Lin, Jianhong, Zhao, Jianjun

“…Cisplatin chemotherapy is standard care for many cancers but is toxic to the kidneys. How this toxicity occurs is uncertain. In this study, we identified…”
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Reported Events Associated With Spine Robots: An Analysis of the Food and Drug Administration’s Manufacturer and User Facility Device Experience Database by Kirchner, Gregory J., Kim, Andrew H., Kwart, Ariel H., Weddle, John B., Bible, Jesse E.

“…Study Design Cross-Sectional Analysis Objectives To summarize medical device reports (MDRs) between August 1, 2017 and November 30, 2021 relating to…”
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119. Adverse events associated the barricaid annular closure device: an analysis of the FDA MAUDE database by Graefe, Steven, Kirchner, Gregory J., Kwart, Ariel, Rowe, Nicholas, Bible, Jesse E.

“…The Food and Drug Administration (FDA) maintains the Manufacturer and User Facility Device Experience (MAUDE) database for reporting adverse events associated…”
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CD44 v5 domain inhibition represses the polarization of Th2 cells by interfering with the IL‐4/IL‐4R signaling pathway by Yang, Chun, Lin, Jianhong, Liang, Hongyan, Xue, Li, Kwart, Ariel, Jiang, Meng, Zhao, Jianjun, Ren, Huan, Jiang, Xiaofeng, Munshi, Nikhil C

“…The balance between T helper type 1 (Th1) and T helper type 2 (Th2) cells is critical for both innate and acquired immune reactions. However, the precise…”
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Developmental dysplasia of the hip and ultrasound reading by pediatric orthopedic surgeons: a pilot study by Kwart, Ariel, Pacana, Matthew, Otsuka, Norman, Piazza, Brian, Armstrong, Douglas, Shaw, Brian, S. Segal, Lee, Sorenson, Scott, Fortuna, Kristine, Abzug, Joshua, Hennrikus, William

“…Ultrasound is an imaging modality utilized for early detection and follow-up of developmental dysplasia of the hip (DDH) in infants. Traditionally, pediatric…”
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Blocking Specific CD44 Splicing Variant Isoform Inhibits the Differentiation of Th-2 Cells through Interfering with IL-4/IL-4R Signaling Pathway by Yang, Chun, Lin, Jianhong, Liang, Hongyan, Kwart, Ariel, Jiang, Meng, Zhao, Jianjun, Jiang, Xiaofeng, Munshi, Nikhil C.

“…The polarization of naïve CD4+ T cells may initiate multiple reactions in immune system. The balance between Th1 and Th2 cells is critical for innate and…”
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A Single Gene-Mediated Perturbation of the Human Genome Leads to Malignant Transformation in a Murine Transgenic Model by Lin, Jianhong, Yang, Chun, Xue, Li, Wang, Zhenkui, Xu, Yan, Samur, Mehmet Kemal, Zhao, Jianjun, Kwart, Ariel, Shammas, Masood A., Jiang, Xiaofeng, Kwok-Kin, Wong, Carrasco, Ruben D., Anderson, Kenneth C, Munshi, Nikhil

“…We hypothesized that induction or activation of a gene that directly affects DNA integrity can provide a tool for ongoing genomic changes in a cell and may…”
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Extensor Carpi Ulnaris Tendon Anatomy May Mimic Tears by Erickson, John, Kwart, Ariel, Steven Yang, S

“…Asymptomatic, incidental extensor carpi ulnaris (ECU) tendon abnormalities are frequently noted on imaging studies of the wrist. The aim of this investigation…”
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Apurinic/Apyrimidinic Endonuclease 1 Induced Genomic Instability Causes T-Cell Acute Lymphoblastic Leukemia in Zebrafish by Lin, Jianhong, Yang, Chun, Kwart, Ariel, Zhao, Jianjun, Samur, Mehmet K, Zhang, Weihong, Nanjappa, Purushothama, Calimeri, Teresa, Ren, Xiubao, Ma, Dongdong, Jiang, Xiaofeng, Zhou, Yi, Shammas, Masood, Anderson, Kenneth C., Aster, Jon C., Zon, Leonard I., Handin, Robert I., Munshi, Nikhil C.

“…Genomic instability is not only a hallmark of cancer, but potentially a primary mechanism for its occurrence. DNA repair mechanisms play a protective role…”
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A Clinically Relevant Zebrafish in Vivo Model of Human Multiple Myeloma (MM) to Study Disease Biology and Preclinical Therapeutic Efficacy by Zhang, Weihong, Lin, Jianhong, Ma, Dongdong, Kwart, Ariel H, Ramachandran, Aravind, He, Shirley, Swagata, Sharma, Tai, Yu-Tzu, Anderson, Kenneth C., Handin, Robert I, Munshi, Nikhil C

“…Abstract 4078 Although a number of murine models of human MM have been developed and the SCID-hu murine model allows for growth of primary MM cells, these…”
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