Search Results - "Kwan, T K"

Absence of MyD88 Signaling Induces Donor-Specific Kidney Allograft Tolerance by HUILING WU, NOORDMANS, Gerda A, O'BRIEN, Maya R, JIN MA, ZHAO, Cathy Y, ZHANG, Geoff Y, KWAN, Tony K. T, ALEXANDER, Stephen I, CHADBAN, Steven J

“…Toll-like receptors (TLRs) play a fundamental role in innate immunity and provide a link between innate and adaptive responses to an allograft; however,…”
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Dichlorodiphenylchloroethylene Elevates Cytosolic Calcium Concentrations and Oscillations in Primary Cultures of Human Granulosa-Lutein Cells by YOUNGLAI, E. V, KWAN, T. K, KWAN, C.-Y, LOBB, D. K, FOSTER, W. G

“…1,1-Dichloro-2,2-bis(p-chlorophenyl)ethylene (DDE), a metabolite of DDT (1,1-dichlorodiphenyltrichloroethane), is a persistent hormonally active environmental…”
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Non-genomic action of estradiol and progesterone on cytosolic calcium concentrations in primary cultures of human granulosa-lutein cells by Younglai, E.V., Wu, Y.J., Kwan, T.K., Kwan, C.-Y.

“…BACKGROUND: The present study examined whether the sex steroids, estradiol and progesterone, could alter cytoplasmic calcium concentrations ([Ca2+]cyt) in…”
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Pregnenolone metabolites in rat testis: endogenous concentrations, and intracellular distribution in whole testes during incubation in vitro by Pertiwi, A.K.D, Kwan, T.K, Gower, D.B

“…The intracellular movements of pregnenolone in rat testes were investigated. Whole testes were incubated in the presence or absence of pregnenolone (2.5 mM) in…”
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Effect of calcium on the vascular contraction induced by cobra venom cardiotoxin by Kwan, CY, Kwan, TK, Huang, SJ

“…Summary 1. The cytotoxic effects of cardiotoxin (CTX) purified from Cobra venom were tested in endothelium‐denuded rat aortic ring preparations in tissue organ…”
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GC-MS studies of 16-androstenes and other C19 steroids in human semen by Kwan, T K, Trafford, D J, Makin, H L, Mallet, A I, Gower, D B

“…Human semen was examined for the presence of 16-androstenols, 16-androstenones and androgens. Extracts were analysed by gas chromatography-mass spectrometry…”
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Use of gas chromatographic-mass spectrometric techniques in studies of androst-16-ene and androgen biosynthesis in human testis; cytosolic specific binding of 5α-androst-16-en-3-one by Kwan, T.K, Kraevskaya, M.A, Makin, H.L.J, Trafford, D.J.H, Gower, D.B

“…Homogenates of histologically normal human testis from three men were incubated separately with pregnenolone, 16-dehydropregnenolone, 5α-pregnane-3,20-dione,…”
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Dichlorodiphenylchloroethylene Elevates Cytosolic Calcium Concentrations and Oscillations in Primary Cultures of Human Granulosa-Lutein Cells1 by Younglai, E. V, Kwan, T. K, Kwan, C-Y, Lobb, D. K, Foster, W. G

“…1,1-Dichloro-2,2-bis(p-chlorophenyl)ethylene (DDE), a metabolite of DDT (1,1-dichlorodiphenyltrichloroethane), is a persistent hormonally active environmental…”
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BCR-ABL mutational studies for predicting the response of patients with chronic myeloid leukaemia to second-generation tyrosine kinase inhibitors after imatinib failure by Kwan, T K, Ma, Edmond S K, Chan, Y Y, Wan, Thomas S K, Liu, Herman S Y, Sim, Joycelyn P Y, Yeung, Y M, Lie, Albert K W, Yip, S F

“…Imatinib is the standard treatment for chronic myeloid leukaemia. BCR-ABL kinase domain mutation is the commonest mechanism implicated in imatinib resistance…”
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Biosynthesis of androgens and pheromonal steroids in neonatal porcine testicular preparations by Kwan, T.K., Orengo, C., Gower, D.B.

“…The biosynthesis of testosterone and 4-androstene-3,17-dione and some 16-androstenes has been studied in homogenates or subcellular fractions of testes from…”
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Effects of Panax notoginseng saponins on vascular endothelial cells in vitro by Kwan, C Y, Kwan, T K

“…To investigate the inhibition of endothelium-dependent in vitro vascular relaxation induced by the total saponins (gensenosides) from Panax notoginseng (PNS)…”
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Effect of oxytocin on plasma testosterone levels in the male macaques (Macaca fascicularis) by Tan, G J, Kwan, T K

“…The effect of oxytocin on testicular function was examined in the adult male long-tailed macaques (Macaca fascicularis). The monkeys were either infused with…”
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Intermediates in 16-androstene biosynthesis in neonatal porcine testis by Kwan, T.K., Honour, J.W., Gower, D.B.

“…The metabolism of pregnenolone has been studied in microsomal preparations of testes from 3-week old piglets. Metabolites identified after derivatization by…”
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The use of steroid profiling in the resolution of pregnenolone metabolites from porcine testicular preparations by Kwan, T K, Taylor, N F, Gower, D B

“…The behaviour of 22 steroids has been examined by capillary gas chromatographic profiling, and the identities of the steroids confirmed by mass spectrometry…”
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Identification of 16-dehydropregnenolone as an intermediate in 16-androstene biosynthesis in neonatal porcine testicular microsomes by Kwan, T.K., Taylor, N.F., Watson, D., Gower, D.B.

“…The biosynthesis of 16-androstenes has been studied in neonatal porcine testicular microsomes using 17-hydroxypregnenolone and 16-dehydropregnenolone,…”
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Tetrandrine inhibits Ca2+ release-activated Ca2+ channels in vascular endothelial cells by Kwan, C Y, Leung, Y M, Kwan, T K, Daniel, E E

“…The effects of tetrandrine (TET), a Ca2+ antagonist of bis-benzylisoquinoline alkaloid origin, on cultured single bovine pulmonary artery endothelial cells…”
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Steroid profiling in the study of rat testicular steroidogenesis by Kwan, T K, Pertiwi, A K, Taylor, N F, Gower, D B

“…Twenty authentic steroids, derivatized as O-methyl oximes (MO), trimethylsilyl (TMS) ethers or as MO-TMS ethers have been subjected to capillary gas…”
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Inhibition of rat testicular microsomal steroidogenesis by oxytocin and metyrapone by Kwan, T K, Gower, D B

“…Capillary gas chromatographic 'steroid profiling' has been utilised to separate and quantify the metabolites (derivatized as methyloximes and/or trimethylsilyl…”
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Pregnenolone metabolism in testicular homogenates of macaques (Macaca fascicularis): some effects of relaxin and freezing by Kwan, T K, Poh, C H, Perumal, R, Gower, D B

“…The metabolism of varying quantities of pregnenolone has been studied in nuclei-free homogenates from Macaca fascicularis testes by using capillary gas…”
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Effect of aspirin, flurbiprofen and indomethacin on porcine testicular steroidogenesis by Kwan, T K, Lim, Y T, Gower, D B

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