Search Results - "Kwan, Richard W"
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A Longitudinal Study of COVID-19 Sequelae and Immunity: Baseline Findings
Published in Annals of internal medicine (01-07-2022)“…A substantial proportion of persons who develop COVID-19 report persistent symptoms after acute illness. Various pathophysiologic mechanisms have been…”
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Clonally expanded CD4⁺ T cells can produce infectious HIV-1 in vivo
Published in Proceedings of the National Academy of Sciences - PNAS (16-02-2016)“…Reservoirs of infectious HIV-1 persist despite years of combination antiretroviral therapy and make curing HIV-1 infections a major challenge. Most of the…”
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Effect of HIV Antibody VRC01 on Viral Rebound after Treatment Interruption
Published in The New England journal of medicine (24-11-2016)“…In these trials, passive administration of VRC01, a broadly neutralizing antibody against human immunodeficiency virus that targets the HIV CD4-binding site,…”
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Overexpression of T-bet in HIV infection is associated with accumulation of B cells outside germinal centers and poor affinity maturation
Published in Science translational medicine (27-11-2019)“…Nearly all chronic human infections are associated with alterations in the memory B cell (MBC) compartment, including a large expansion of CD19 T-bet MBC in…”
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IgG3 regulates tissue-like memory B cells in HIV-infected individuals
Published in Nature immunology (01-09-2018)“…Immunoglobulin G3 (IgG3) has an uncertain role in the response to infection with and vaccination against human immunodeficiency virus (HIV). Here we describe a…”
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