Search Results - "Kwak, Shin"

Modular Multilevel Converters (MMCs) Controlled by Model Predictive Control With Reduced Calculation Burden by Gutierrez, Bryan, Sang-Shin Kwak

“…Model predictive control (MPC) for modular multilevel converter (MMC) systems has drawn attention among researchers in recent years due to its straightforward…”
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The molecular link between inefficient GluA2 Q/R site-RNA editing and TDP-43 pathology in motor neurons of sporadic amyotrophic lateral sclerosis patients by Yamashita, Takenari, Kwak, Shin

“…Abstract TAR DNA-binding protein (TDP-43) pathology and reduced expression of adenosine deaminase acting on RNA 2 (ADAR2), which is the RNA editing enzyme…”
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Cell death cascade and molecular therapy in ADAR2-deficient motor neurons of ALS by Yamashita, Takenari, Kwak, Shin

“…[Display omitted] •Disruption of nuclear pore complex (NPC) plays a pivotal pathogenic role in ALS.•Nucleoporins, the NPC components, are cleaved by…”
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Novel Flux-Weakening Control of an IPMSM for Quasi-Six-Step Operation by Kwon, Tae-Suk, Choi, Gi-Young, Kwak, Mu-Shin, Sul, Seung-Ki

“…This paper proposes a novel flux-weakening control algorithm of an interior permanent-magnet synchronous motor for ldquoquasirdquo six-step operation. The…”
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Extracellular RNAs as Biomarkers of Sporadic Amyotrophic Lateral Sclerosis and Other Neurodegenerative Diseases by Hosaka, Takashi, Yamashita, Takenari, Tamaoka, Akira, Kwak, Shin

“…Recent progress in the research for underlying mechanisms in neurodegenerative diseases, including Alzheimer disease (AD), Parkinson disease (PD), and…”
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RNA Editing: A New Therapeutic Target in Amyotrophic Lateral Sclerosis and Other Neurological Diseases by Hosaka, Takashi, Tsuji, Hiroshi, Kwak, Shin

“…The conversion of adenosine to inosine in RNA editing (A-to-I RNA editing) is recognized as a critical post-transcriptional modification of RNA by adenosine…”
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Microfluidic skin chip with vasculature for recapitulating the immune response of the skin tissue by Kwak, Bong Shin, Jin, Seon‐Pil, Kim, Su Jung, Kim, Eun Joo, Chung, Jin Ho, Sung, Jong Hwan

“…There is a considerable need for cell‐based in vitro skin models for studying dermatological diseases and testing cosmetic products, but current in vitro skin…”
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The AMPA receptor antagonist perampanel robustly rescues amyotrophic lateral sclerosis (ALS) pathology in sporadic ALS model mice by Akamatsu, Megumi, Yamashita, Takenari, Hirose, Naoki, Teramoto, Sayaka, Kwak, Shin

“…Both TDP-43 pathology and failure of RNA editing of AMPA receptor subunit GluA2, are etiology-linked molecular abnormalities that concomitantly occur in the…”
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A Hybrid Deep Learning Emotion Classification System Using Multimodal Data by Kim, Dong-Hwi, Son, Woo-Hyeok, Kwak, Sung-Shin, Yun, Tae-Hyeon, Park, Ji-Hyeok, Lee, Jae-Dong

“…This paper proposes a hybrid deep learning emotion classification system (HDECS), a hybrid multimodal deep learning system designed for emotion classification…”
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Profound downregulation of the RNA editing enzyme ADAR2 in ALS spinal motor neurons by Hideyama, Takuto, Yamashita, Takenari, Aizawa, Hitoshi, Tsuji, Shoji, Kakita, Akiyoshi, Takahashi, Hitoshi, Kwak, Shin

“…Abstract Amyotrophic lateral sclerosis (ALS) is the most common adult-onset fatal motor neuron disease. In spinal motor neurons of patients with sporadic ALS,…”
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Autophagy in spinal motor neurons of conditional ADAR2-knockout mice: An implication for a role of calcium in increased autophagy flux in ALS by Sasaki, Soichi, Yamashita, Takenari, Shin, Kwak

“…•Failure of GluA2 RNA editing resulting from ADAR2 down-regulation occurs in ALS.•Conditional ADAR2-knockout mice are the mechanistic model mice for sporadic…”
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Pathological features of glial cells and motor neurons in the anterior horn of the spinal cord in sporadic ALS using ADAR2 conditional knockout mice by Naito, Makiko, Hideyama, Takuto, Teramoto, Sayaka, Saito, Tomoko, Kato, Haruhisa, Terashi, Hiroo, Kwak, Shin, Aizawa, Hitoshi

“…Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease characterized by the selective degeneration of motor neurons (MNs). In the MNs…”
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Calpain-dependent disruption of nucleo-cytoplasmic transport in ALS motor neurons by Yamashita, Takenari, Aizawa, Hitoshi, Teramoto, Sayaka, Akamatsu, Megumi, Kwak, Shin

“…Nuclear dysfunction in motor neurons has been hypothesized to be a principal cause of amyotrophic lateral sclerosis (ALS) pathogenesis. Here, we investigated…”
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Phosphorylated TDP-43 becomes resistant to cleavage by calpain: A regulatory role for phosphorylation in TDP-43 pathology of ALS/FTLD by Yamashita, Takenari, Teramoto, Sayaka, Kwak, Shin

“…•Phosphorylated TDP-43 becomes resistant to cleavage by calpain.•Calpain-dependent TDP-43 fragments are resistant to cleavage by calpain.•Phosphorylated and…”
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Control of an Open-Winding Machine in a Grid-Connected Distributed Generation System by Kwak, Mu-Shin, Sul, Seung-Ki

“…In this paper, a grid-connected distributed generation system, which consists of engine-generator, DC link with multiple energy sources, and inverter, is…”
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Roles of Aging, Circular RNAs, and RNA Editing in the Pathogenesis of Amyotrophic Lateral Sclerosis: Potential Biomarkers and Therapeutic Targets by Hosaka, Takashi, Tsuji, Hiroshi, Kwak, Shin

“…Amyotrophic lateral sclerosis (ALS) is an incurable motor neuron disease caused by upper and lower motor neuron death. Despite advances in our understanding of…”
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Model Predictive Control Method With NP Voltage Balance by Offset Voltage Injection for Three-Phase Three-Level NPC Inverter by Jun, Eun-Su, Nguyen, Minh Hoang, Kwak, Sang-Shin

“…This paper proposes a predictive control method with offset voltage injection for achieving a neutral point (NP) voltage balance of three-phase three-level…”
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Impaired Nucleoporins Are Present in Sporadic Amyotrophic Lateral Sclerosis Motor Neurons that Exhibit Mislocalization of the 43-kDa TAR DNA-Binding Protein by Aizawa, Hitoshi, Yamashita, Takenari, Kato, Haruhisa, Kimura, Takashi, Kwak, Shin

“…Disruption of nucleoporins has been reported in the motor neurons of patients with sporadic amyotrophic lateral sclerosis (sALS). However, the precise changes…”
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Nuclear pore destruction and loss of nuclear TDP-43 in FUS mutation-related amyotrophic lateral sclerosis motor neurons by Aizawa, Hitoshi, Teramoto, Sayaka, Hideyama, Takuto, Kato, Haruhisa, Terashi, Hiroo, Suzuki, Yasuhiro, Kimura, Takashi, Kwak, Shin

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Induced loss of ADAR2 engenders slow death of motor neurons from Q/R site-unedited GluR2 by Hideyama, Takuto, Yamashita, Takenari, Suzuki, Takeshi, Tsuji, Shoji, Higuchi, Miyoko, Seeburg, Peter H, Takahashi, Ryosuke, Misawa, Hidemi, Kwak, Shin

“…GluR2 is a subunit of the AMPA receptor, and the adenosine for the Q/R site of its pre-mRNA is converted to inosine (A-to-I conversion) by the enzyme called…”
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